Image_4_Pharmacokinetic Behavior of Vincristine and Safety Following Intravenous Administration of Vincristine Sulfate Liposome Injection in Chinese Patients With Malignant Lymphom... by Fen Yang (287005)

“…</p><p>Results: In this phase Ia study, a total of eight subjects participated. VCR elimination from the circulation after injection of VSLI was characterized by a significantly increased maximum concentration (C_max, 86.6 ng/mL) and plasma area under the plasma concentration-time curve from zero to infinity (AUC_0-Inf, 222.1 ng/mL h), markedly decreased distribution volume (V_z, 224.1 L) and plasma clearance (CL, 8.9 L/h) compared to lower C_max (26.6 ng/mL) and AUC_0-Inf (95.1 ng/mL h), larger V_z (688.8 L) and CL (22.1 L/h) for VSI. …”

Differences in brain activation between high- and low-sensitization responders during post-burn mechanical noxious stimulation. by Mohammad Sohail Asghar (685685)

Effects of age of exercise onset on body composition across the lifespan. by Agnieszka Mika (306138)

TLR4 and NF-κB signaling pathway is required for the reduction of let-7b expression in response to <i>H.pylori</i> infection. by Gui-gen Teng (380044)

“…<p>(A) TKA-242 (1 uM) decreased the expression of TLR4 protein in AGS and GES-1 cells with <i>H.pylori</i>-infection. …”

SOCS3 regulated the fate of HSCs. by Yu-xiao Liu (146872)

“…Bar = 50 μm. (B) BFU-E and CFU-E derived from shSOCS3-1 CD34⁺ cells. …”

Mechanism of SFK phosphorylation and negative regulation of PKA in chicken sperm. by Chathura Priyadarshana (9635328)

“…<p>Sperm were incubated with 0–50 μM H-89 (PKA inhibitor), 25 μM KH7 (sAC inhibitor), 50 μM MDL (tmAC inhibitor), 0–250 μM PTP inhibitor, or EGTA-AM in the presence or absence of SKI606 and SU6656 and then subjected to immunodetection for p-SFK-Y416 or p-PKAs. …”

Table_1_Evapotranspiration Intensification Over Unchanged Temperate Vegetation in the Baltic Countries Is Being Driven by Climate Shifts.DOCX by Bruno Montibeller (10719348)

Data_Sheet_1_Correlation Between Amygdala Nuclei Volumes and Memory in Cognitively Normal Adults Carrying the ApoE ε3/ε3 Allele.docx by Wenqing Liao (1784479)

DELTA-1/NOTCH signaling in the caudal spinal cord of chick embryos. by Barbara Hämmerle (36261)

“…<p>A–A′. Confocal projection over 50 µm from a dorsal aspect of the prospective spinal cord at the level of the 12^th and 13^th somites counted from rostral of a HH13 chick embryo that was electroporated with NICD at stage HH10 when that region was part of the PNTZ. …”

<em>Nigella sativa</em> (Black Cumin) Seed Extract Alleviates Symptoms of Allergic Diarrhea in Mice, Involving Opioid Receptors by Swantje C. Duncker (154707)

“…<em>N. sativa</em> seed extract, thymoquinone, and U50'488 also decreased intestinal mast cell numbers and plasma mouse mast cell protease-1 (MMCP-1). …”

DataSheet1_Tanreqing Inhibits LPS-Induced Acute Lung Injury In Vivo and In Vitro Through Downregulating STING Signaling Pathway.DOCX by Yu-Qiong He (5568263)

Improving Detection of Arrhythmia Drug-Drug Interactions in Pharmacovigilance Data through the Implementation of Similarity-Based Modeling by Santiago Vilar (148764)

Whitebark Pine, Population Density, and Home-Range Size of Grizzly Bears in the Greater Yellowstone Ecosystem by Daniel D. Bjornlie (521204)

Trajectories of Antidepressant Medication before and after the Onset of Unemployment by Subsequent Employment Experience by Taina Leinonen (569819)

DataSheet2_Tanreqing Inhibits LPS-Induced Acute Lung Injury In Vivo and In Vitro Through Downregulating STING Signaling Pathway.DOCX by Yu-Qiong He (5568263)

Real-world weight changes in people with HIV-1 at risk of weight gain (female, Black or Hispanic) switching from integrase strand transfer inhibitors: supplementary figure by Prina Donga (8899571)

Platelet thrombus formation on immobilized VWF in the presence of HbS. by Gowtham K. Annarapu (2622811)

“…Further the thrombus was decreased in presence of 5 μM AA1-50 <b>(B3)</b> but not in presence of control peptide <b>(B4)</b>.…”

Effect of cue-contrast dependence on temporal properties of population activity patterns under ON-/OFF-LMI stimulus paradigm. by Yuxiu Shao (8953262)

“…<p>Y-axis represents the distance from this position to the edge of the model cortex (edge near the position of the stimulus initiation), and x-axis records the moment when the activity of this position reaches 80% of its maximum amplitude. We summarize the results of traveling wave positions as a function of time under identical ON-/OFF-LMI stimulus paradigm, except for the contrast of the initial cue-square, which reduces from 100% to 50% of the contrast fed into the model in <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1007265#pcbi.1007265.g003" target="_blank">Fig 3F</a>. …”

Simulations of the PUABM match key features of clinical images. by Cordelia Ziraldo (221649)

Serine 26 in the PomB Subunit of the Flagellar Motor Is Essential for Hypermotility of <i>Vibrio cholerae</i> by Petra Halang (561390)