Oral Efficacy of Apigenin against Cutaneous Leishmaniasis: Involvement of Reactive Oxygen Species and Autophagy as a Mechanism of Action by Fernanda Fonseca-Silva (356488)

“…</p><p>Methodology/Principal Finding</p><p>Apigenin reduced the infection index in a dose-dependent manner, with IC₅₀ values of 4.3 μM and a selectivity index of 18.2. …”

Glucose decreases the ability of HNF4α to activate the transcription of the <i>NR2F2</i> proximal promoter and to bind its chromatin target. by Marie Boutant (164748)

IQG-607 decreases the infection of macrophages by <i>L</i>. <i>braziliensis</i> amastigotes. by Camila F. Amorim (676792)

The concentration-dependent decrease of intracellular D-Ser concentrations produced by incubation of PC-12 cells with the enantiomers of ketamine (Ket) and its major metabolites ex... by Nagendra S. Singh (2620399)

Map of the study area, representing the 50 provinces, divided between the 6 different regions. by Jacopo Cerri (6271958)

Kif2a accumulation at the base of <i>Ttbk2</i>^{<i>sca11/gt</i>} cilia causes instability. by Emily Bowie (543704)

Potent Sensitisation of Cancer Cells to Anticancer Drugs by a Quadruple Mutant of the Human Deoxycytidine Kinase by Safiatou T. Coulibaly (816058)

“…Importantly, a remarkable effect is also observed in treatments with the anticancer compound cytarabine (AraC), for which a 10,000 fold decrease in IC50 occurred. …”

The loss of Sad kinases leads to a decrease in the number of neuronal progenitors in the cortex. by Pratibha Dhumale (5146484)

Prorocentin-5: A Cytotoxic Polyketide from the Benthic Marine Dinoflagellate <i>Prorocentrum lima</i> by Yunseok Choi (5625245)

Subjects:

(A) Kaplan-Meier survival curves showing 28-day survival rates between the two groups;(B) ROC analysis of death risk factors in SFTS patients with HLH. by Bo Zhang (6559)

Prognosis and risk factors of chronic kidney disease progression in patients with diabetic kidney disease and non-diabetic kidney disease: a prospective cohort CKD-ROUTE study by Shengnan Chen (3595319)

“…The secondary endpoints were all-cause death and the development of cardiovascular disease (CVD) events. We found that DKD patients have a higher risk to develop 50% eGFR decline endpoint (HR:2.30, 95%CI [1.48–3.58], <i>p</i> < 0.001) and KRT endpoint (HR:1.64, 95%CI [1.13–2.37], <i>p</i> < 0.05) than NDKD patients. …”

The ATR IR signal decreases with decreasing dilutions of cells. by Allison L. Stelling (392086)

“…<p>Shown is a box plot for serial dilutions of a glioblastoma cell suspension. …”

Stroma decreases spheroid size by decreasing cell width. by Karen F. Chambers (224337)

Fermentation must reducing sugar (A, strain A; B, strain B; C, strain F) and fermentation ethanol concentration (D, strain A; E, strain B; F, strain F) for <i>S. cerevisiae</i> str... by Xiang-yu Sun (748032)

Galiellalactone decreases the proportion of ALDH+ prostate cancer cells in vitro and the ALDH1A1 expression in vivo. by Rebecka Hellsten (348459)

“…<p>A. DU145 and LNCaP-IL6 cells were treated with galiellalactone (5–50 µM) for 24 h and subjected to ALDEFLUOR® assay. …”

Data_Sheet_2_Immunotolerant p50/NFκB Signaling and Attenuated Hepatic IFNβ Expression Increases Neonatal Sensitivity to Endotoxemia.docx by Sarah McKenna (5040047)

“…<p>Sepsis is a major cause of neonatal morbidity and mortality. …”

Data_Sheet_1_Immunotolerant p50/NFκB Signaling and Attenuated Hepatic IFNβ Expression Increases Neonatal Sensitivity to Endotoxemia.PDF by Sarah McKenna (5040047)

“…<p>Sepsis is a major cause of neonatal morbidity and mortality. …”

Parameters for the seven ODE models. by Hope Murphy (8843516)

Cost-effectiveness and budget impact of immediate antiretroviral therapy initiation for treatment of HIV infection in Côte d’Ivoire: A model-based analysis by Eric N. Ouattara (6890174)

IC₅₀ (left) and <i>ε</i>_max (right) measurement time dependence for all seven models. by Hope Murphy (8843516)