Image_2_The relationship between central obesity and risk of breast cancer: a dose–response meta-analysis of 7,989,315 women.jpg by Hongyang Chen (410527)

“…Regarding the BC subtype, central obesity is proven to be a risk of ER+ and ER- BCs. The dose–response analysis revealed that when BMI (during premenopausal) exceeded 23.40 kg/m², the risk of BC began to decrease, and WC higher than 83.80 cm or WHR exceeded 0.78 could efficiently increase the BC risk.…”

Table_4_The relationship between central obesity and risk of breast cancer: a dose–response meta-analysis of 7,989,315 women.DOCX by Hongyang Chen (410527)

“…Regarding the BC subtype, central obesity is proven to be a risk of ER+ and ER- BCs. The dose–response analysis revealed that when BMI (during premenopausal) exceeded 23.40 kg/m², the risk of BC began to decrease, and WC higher than 83.80 cm or WHR exceeded 0.78 could efficiently increase the BC risk.…”

Table_2_The relationship between central obesity and risk of breast cancer: a dose–response meta-analysis of 7,989,315 women.DOCX by Hongyang Chen (410527)

“…Regarding the BC subtype, central obesity is proven to be a risk of ER+ and ER- BCs. The dose–response analysis revealed that when BMI (during premenopausal) exceeded 23.40 kg/m², the risk of BC began to decrease, and WC higher than 83.80 cm or WHR exceeded 0.78 could efficiently increase the BC risk.…”

Table_5_The relationship between central obesity and risk of breast cancer: a dose–response meta-analysis of 7,989,315 women.DOCX by Hongyang Chen (410527)

“…Regarding the BC subtype, central obesity is proven to be a risk of ER+ and ER- BCs. The dose–response analysis revealed that when BMI (during premenopausal) exceeded 23.40 kg/m², the risk of BC began to decrease, and WC higher than 83.80 cm or WHR exceeded 0.78 could efficiently increase the BC risk.…”

MAP3K19 siRNA inhibits cigarette smoke-induced pulmonary inflammation. by Stefen A. Boehme (2657068)

“…<p>The acute model of cigarette smoke exposure subjected mice to cigarette smoke (7 cigarettes over a 1.75 hour period) on days 1 & 2, and dosed with either PBS, non-sense siRNA (100 μg in 50 μl volume), MAP3K19 siRNA or the CXCR-2 antagonist SB 265610 (10 mg/kg, p.o.) on days 1, 2 & 3 (n = 5 mice per treatment group). …”

Assessing the usage of end-of-life tire pyrolysis oil as an alternative fuel in a diesel engine in the point of energy, exergy, exergoeconomic, exergoenviroeconomic, and sustainabi... by Talha Ertürk (19715855)

“…<p>The present study examines the utilization of fuel blends comprising waste tire pyrolysis oil (WTPO) at varying ratios (10%, 20%, 30%, and 40%) in a compression-ignition (CI) engine at different loads (25%, 50%, 75%, and 100%). …”

ERR2/3 may in part operate through <i>Kcna10</i> to promote a gamma motor neuron-like biophysical signature. by Mudassar N. Khan (14290428)

“…<b>(C)</b> Reporter tdTomato fluorescence driven by wild-type (WT) <i>Kcna10</i> promoter is boosted by ERR2 cotransfection (red, <i>n</i> = 102) in chick motor neurons when compared to control (gray, <i>n</i> = 100) and decrease in tdTomato reporter fluorescence upon mutating the ERR2/3 binding sites (black, <i>n</i> = 101). …”

Do pheromone traps help to reduce new attacks of Ips typographus at the local scale after a sanitary cut ? Supplements and detailed statistical analysis by Gilles San Martin (3552875)

“…</p> <p>In this two-year study (2020-2021), at the peak of a severe outbreak in Belgium, we quantified the wood volume and presence/absence of new attacks at 126 sites attacked during the previous year and within 100 m from the initial attack. …”

CBP-1 is critical for <i>mir-80</i>(Δ) healthspan benefits, and is a candidate direct binding target of miR-80. by Mehul Vora (94793)

“…<p><a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1003737#pgen-1003737-g006" target="_blank">Fig. 6A</a>. …”

PrP^CGPIThy-1 L150 mice show a delay to terminal disease and altered neuropathology upon prion infection. by Berta Puig (344828)

“…Chart underneath shows mean relative intensity of PrP referred to actin where WTPrP^C samples are set to 100% as a reference (error bars are SEM; n = 5 for each genotype). …”

Effect of Selenite and Selenate Application on Mineral Composition of Lettuce Plants Cultivated Under Hydroponic Conditions: Nutritional Balance Overview Using a Multifaceted Study by Emanueli do Nascimento da Silva (3897079)

“…Selenate promoted the absorption of Mo and S and the reduction of K, Mn and P, meanwhile selenite increased Mn and decreased Mo accumulation. Copper and Fe absorption was negatively affected, Ca and Mg showed a slight increase, and Na and Zn were not affected by Se species. …”

Analysis of targeted MLX deletion in Sertoli cells. by Patrick A. Carroll (11586792)

“…<p>(<b>A</b>) IF for the Sertoli cell marker SOX9 in WT and MLX^KO testes with acellular tubules indicated with asterisks (100×, scale bar = 400 uM). …”

Data_Sheet_3_An Evaluation of Three Ways of Communicating Carrier Status Results to the Parents of Children in a Neonatal Sickle Cell Screening Programme.PDF by Christelle Rémus (8995493)

“…</p><p>Method: In a randomized study, we contacted 300 couples of parents after their child had been identified as a SCD carrier in the French national newborn screening programme: 100 couples received an information letter (the standard procedure in France: arm A), 100 couples received a letter and then a follow-up phone call (arm B), and 100 received a letter and then three follow-up text messages at 5-day intervals (arm C). …”

Data_Sheet_1_An Evaluation of Three Ways of Communicating Carrier Status Results to the Parents of Children in a Neonatal Sickle Cell Screening Programme.PDF by Christelle Rémus (8995493)

“…</p><p>Method: In a randomized study, we contacted 300 couples of parents after their child had been identified as a SCD carrier in the French national newborn screening programme: 100 couples received an information letter (the standard procedure in France: arm A), 100 couples received a letter and then a follow-up phone call (arm B), and 100 received a letter and then three follow-up text messages at 5-day intervals (arm C). …”

Data_Sheet_2_An Evaluation of Three Ways of Communicating Carrier Status Results to the Parents of Children in a Neonatal Sickle Cell Screening Programme.PDF by Christelle Rémus (8995493)

“…</p><p>Method: In a randomized study, we contacted 300 couples of parents after their child had been identified as a SCD carrier in the French national newborn screening programme: 100 couples received an information letter (the standard procedure in France: arm A), 100 couples received a letter and then a follow-up phone call (arm B), and 100 received a letter and then three follow-up text messages at 5-day intervals (arm C). …”

Image4_The galectin-3 inhibitor selvigaltin reduces liver inflammation and fibrosis in a high fat diet rabbit model of metabolic-associated steatohepatitis.JPEG by Paolo Comeglio (14195007)

“…Selvigaltin (previously known as GB1211) is a novel orally active galectin-3 small molecule inhibitor that has high affinity for galectin-3 (human K_D = 25 nM; rabbit K_D = 12 nM) and high oral bioavailability in rabbits and man. …”

Image6_The galectin-3 inhibitor selvigaltin reduces liver inflammation and fibrosis in a high fat diet rabbit model of metabolic-associated steatohepatitis.JPEG by Paolo Comeglio (14195007)

“…Selvigaltin (previously known as GB1211) is a novel orally active galectin-3 small molecule inhibitor that has high affinity for galectin-3 (human K_D = 25 nM; rabbit K_D = 12 nM) and high oral bioavailability in rabbits and man. …”

Image3_The galectin-3 inhibitor selvigaltin reduces liver inflammation and fibrosis in a high fat diet rabbit model of metabolic-associated steatohepatitis.JPEG by Paolo Comeglio (14195007)

“…Selvigaltin (previously known as GB1211) is a novel orally active galectin-3 small molecule inhibitor that has high affinity for galectin-3 (human K_D = 25 nM; rabbit K_D = 12 nM) and high oral bioavailability in rabbits and man. …”

Table2_The galectin-3 inhibitor selvigaltin reduces liver inflammation and fibrosis in a high fat diet rabbit model of metabolic-associated steatohepatitis.DOCX by Paolo Comeglio (14195007)

“…Selvigaltin (previously known as GB1211) is a novel orally active galectin-3 small molecule inhibitor that has high affinity for galectin-3 (human K_D = 25 nM; rabbit K_D = 12 nM) and high oral bioavailability in rabbits and man. …”

Image1_The galectin-3 inhibitor selvigaltin reduces liver inflammation and fibrosis in a high fat diet rabbit model of metabolic-associated steatohepatitis.JPEG by Paolo Comeglio (14195007)

“…Selvigaltin (previously known as GB1211) is a novel orally active galectin-3 small molecule inhibitor that has high affinity for galectin-3 (human K_D = 25 nM; rabbit K_D = 12 nM) and high oral bioavailability in rabbits and man. …”