SOCS-1 silencing enhances cytokine production and stimulatory capacity of mo-DCs. by Meenakshi Sachdeva (817136)

“…(a) Mo-DCs treated with siSOCS-1 had around 50% decrease in the expression of SOCS-1 gene which was significantly less than the control cells (p<0.05). …”

Morphological changes in NFs for RF-induced rat sciatic nerve injury. by Samjin Choi (358532)

“…CO, control; SH, sham; PRF, pulsed RF; CRF, continuous RF. Scale bar = 50 µm. (B) Definition of NFs for counting. M, myelin; A, axon. …”

Vascular permeability visualized via FITC-dextran staining. by Steven Hyun Seung Lee (12884158)

“…<p>(a) Significant amounts of retinal vessel leakage, appearing as indistinct regions of blurred staining, can be observed throughout the retinas of the sham-treated STZ-induced diabetic mouse models and those administered with the virus vector containing a control shRNA, whereas rAAV2-shmTOR-SD injection resulted in a marked decrease in vascular permeability. Scale bar = 50 μm. …”

Analysis of HNE-mediated UCP1 modification. by Elena A. Malingriaux (477327)

“…Membrane conductance decrease in the presence of Cys, Lys, and His blockers. …”

Pro-resorptive activity of human osteoarthritis subchondral bone osteoblasts by Steeve Kwan Tat (87212)

“…They are expressed as the mean resorbed surface per total surface upon treatment with the factors. …”

Cross-frequency coupling during SWA. by Miguel Valencia (347021)

“…<p>A, Comodulogram in the ranges 0.2–3.5 and 5–100 Hz for one representative animal, revealing that the phase of the slow oscillations modulates the amplitude of spindles and gamma oscillations; no other frequencies are modulated during SWA. …”

QD-BDNF probes activate TrkB signaling and induce neuronal survival. by Anke Vermehren-Schmaedick (551619)

“…(C) QD-BDNF-dependent survival is TrkB specific as pre-block with anti-TrkB receptors and subsequent QD-BDNF treatment decreased NG neurons survival (ANOVA, p<0.0001, Dunnett's post-hoc test, n = 5). …”

Preponderance of disease-associated transcripts upregulated in Th17 and in vitro differentiated Th1 cells. by Wei Zhang (405)

Directed evolution of HIV-1 to utilize CD4^low target cells. by David Beauparlant (3491435)

“…<b>(C)</b> <u>Adaptation to CD4</u>^<u>low</u> <u>targets increases sensitivity to CD4-IgG</u>₂ <u>(PRO542).</u> Mean neutralization sensitivity (IC50) of envelope-pseudotyped viruses on TZM-bl cells derived from two to seven independent assays (error bars = SD) are shown. …”

DNA damage evoked by <i>K. pneumoniae</i> 1084 infection <i>in vivo</i>. by Yi-Chyi Lai (213766)

“…Each value is the mean ± SEM for 3 mice. An asterisk (*) represents a significant decrease in the Δ<i>clbA</i>-infected group in comparison with the <i>K. pneumoniae</i> 1084-infected group by the Mann-Whitney U test (two-tailed; <i>P</i><0.05). …”

Effects of Low Dose Metformin on Metabolic Traits in Clozapine-Treated Schizophrenia Patients: An Exploratory Twelve-Week Randomized, Double-Blind, Placebo-Controlled Study by Chih-Chiang Chiu (750477)

“…Moreover, patients in the metformin at 500 mg/d and 1000 mg/d groups had a significant decrease in body mass index (BMI) after 12 weeks, with the mean decrease being 0.70 and 0.50 kg/m², respectively. …”

Effect of ligand on the on-state ATF levels. by Santhosh Palani (259661)

“…F. Increasing L_A from 0, with L_B constant at 100, decommits the cell to the bipotent state (decrease in ATF_B to intermediate level) and then again to the committed lineage A state (decrease in ATF_B to low level) after reaching the corresponding threshold concentrations (solid blue line). …”

Baroreceptor reflex sensitivity for renal sympathetic nerve activity (rSNA). by Heder F. G. Estrela (2602684)

“…<p>(<b>A</b>) Linear regression graph showing: depressor response—the reflexive increase in rSNA to decrease the mean arterial pressure (MAP) produced by ramp infusion of sodium nitroprusside (200μg/ml, 6ml/h, iv); and pressor response—rSNA decrease reflex response to increase MAP produced by ramp infusion of phenylephrine (100μg/ml, 6ml/h, iv) for 60 seconds in the control and bile duction ligation (BDL) groups. n, number of rats *P < 0.05 compared to control group (Sutdent’t test). …”

Effect of Irradiation Time and Competitive Inhibitors: Adenosine deaminase (cADA) was subjected to UV exposure in the presence and absence of known competitive inhibitors of cADA. by Shikha Mahajan (691439)

“…<p>a) Effect of irradiation time on the labeling cADA with the probe <b>1</b>: lane 1 represents control cADA without any probe (ctr), and lanes 2–7 represent cADA irradiated with UV light for 0 to 300 seconds. b) Inhibition of cADA labeling by nebularine <b>9</b>: lanes 1–6 show the decrease in cADA labeling by the probe <b>1</b> with an increase in the concentration of nebularine <b>9</b>, from molar ratios of [nebularine]/[cADA] of 0 to 800. c) Inhibition of cADA labeling by 8-azido adenosine <b>10</b>: lanes 1–6 shows the decrease in cADA labeling by the probe <b>1</b> with an increase in the concentration of 8-azidoadenosine <b>10</b>, from molar ratios of [8-azidoadenosine]/[cADA] of 0 to 100.…”

Baroreceptor reflex sensitivity for splanchnic sympathetic nerve activity (sSNA). by Heder F. G. Estrela (2602684)

“…<p>(<b>A</b>) Linear regression graph showing: depressor response—the reflexive increase in sSNA to decrease the mean arterial pressure (MAP) produced by ramp infusion of sodium nitroprusside (200μg/ml, 6ml/h, iv); and pressor response—sSNA decrease reflex response to increase MAP produced by ramp infusion of phenylephrine (100μg/ml, 6ml/h, iv) for 60s in the control and bile duction ligation (BDL) groups. n, number of rats *P < 0.05 compared to control group (Sutdent’<i>t</i> test). …”

Climate Change and the Distribution of Neotropical Red-Bellied Toads (<i>Melanophryniscus</i>, Anura, Amphibia): How to Prioritize Species and Populations? by Caroline Zank (586679)

“…We used the estimated decrease in specific suitable climatic range to set a conservation priority rank for <i>Melanophryniscus</i> species. …”

Establishment of Replicating Mycobacterium tuberculosis in an Aerosol Mouse Model of Infection: Active vs. Chronic Infection by Larry Bowen (5750969)

“…The mean deposited dose based on recovery of bacteria in lungs post exposure was 3.9E+02 CFU. …”

Aβ-associated impairment of EC network activity in vivo. by Gustavo A. Rodriguez (9268596)

Optogenetic simulation to silence interneurons. by Kwangjun Lee (22226994)

Evaluation of salinity toxicity in biological nitrification effluent using the respirometry technique by Alyne Moraes Costa (6131834)

“…Tests were performed with the addition of increasing concentrations of salt (100, 250, 500, 1,000, 2,000, 4,000, 8,000, 10,000 and 15,000 mg Cl- L-1) in a 5.7 L laboratory bioreactor. …”