Tg9949 mice are prone to neurological dysfunction but do not spontaneously generate prions. by David W. Colby (254454)

“…(<b>E</b>) Brain samples from six aged Tg9949 mice do not seed the formation of recPrP amyloid, as judged by an increase in Thioflavin T fluorescence (top) and by a decrease in the lag phase for amyloid formation (bottom). …”

Inoculation of Tg9949 mice with PrP amyloid, but not other PrP conformations, results in the generation of prions. by David W. Colby (254454)

“…Activity in the ASA was detected by an increase in ThT fluorescence (<b>B and top of panel C</b>) and by a decrease in the mean lag phase for PrP amyloid formation (<b>bottom of panel C</b>). …”

Altered gene pathways in <i>miR-210</i> over-expressing flies. by Paola Cusumano (60521)

“…<i>miR-210</i> over-expressing flies (grey) showed a significant decrease in the optomotor response compared to controls (black). …”

Translation studies with single-molecule resolution. by Luis U. Aguilera (3759934)

“…All simulations correspond to KDM5B for 100 spots and a frame rate of 1 FPS. Error bars represent the standard error of the mean.…”

Expansion models of the CTG repeat expansion in blood and saliva. by Eyleen Corrales (6659279)

Retinal morphology and function is damaged in TALEN <i>clcc1</i>-KO zebrafish. by Lin Li (28817)

“…Cone spectral sensitivity is depressed about 60% in mutants. (g) No background, 50μM CNQX. For signals from ON bipolar cells, which are 2X more sensitive than cone signals, TALEN <i>clcc1</i> mutant responses decrease by over 50%. …”

The effects of variations in coagulation potential on atherogenesis in a spontaneous atherosclerosis model at 35 weeks on a regular chow diet. by Julian I. Borissoff (280594)

VU0183254 reduces OR-mediated currents. by Patrick L. Jones (192712)

“…<b>A.</b> VU0183254 (100 µM) decreased responses to delta-undecalactone (1 µM) and VUAA1 (100 µM) in HEK cells expressing AgOrco+AgOr48. …”

Temperature gradient ddPCR for both DMD ex51-52.2 and DMD ex47-52 assays. by Ruurd C. Verheul (3111144)

Inhibition of inflammation in the brain of P. berghei-infected mice with ECM after treatment. by Nana O. Wilson (399957)

Double knockdown of <i>Gli1/Gli2</i> in XY gonads. by Kathryn S. McClelland (687254)

“…Quantification (<i>n</i> = 2) of steroidogenic cells revealed no change in the number of HSD3β-positive Leydig cells (O; green) or SF1-positive/SOX9-negative pre-Leydig cells (O; red). There was a decrease in the number of SOX9-positve Sertoli cells in the Gli1/2MO treated XY gonads (O; yellow). …”

Quantitative Laser Biospeckle Method for the Evaluation of the Activity of <i>Trypanosoma cruzi</i> Using VDRL Plates and Digital Analysis by Hilda Cristina Grassi (3383654)

“…<i>cruzi</i>, which remains with a similar profile up to 1 hour. A second effect which is dependent on concentrations above 1.25μg/mL and is statistically different from the effect at lower concentrations causes a decrease in the activity of the Biospeckle pattern. …”

Image_1_Normalization of eosinophil count is predictive of oxygen weaning over the course of COVID-19 infection among hospitalized adults during the first wave of 2020 pandemic.tif by Benjamin Davido (2825426)

“…The primary aim was to assess whether eosinophil count normalization predicts a subsequent decrease in oxygen requirements.</p>Results<p>Overall, 132 patients were admitted, with a mean age of 59.0 ± 16.3 years. …”

Data Sheet 1_Thermodynamic integration in combined fuel and power plants producing low carbon hydrogen and power with CCUS.docx by Daniel Mullen (5681870)

“…A first of a kind techno economic analysis concludes that the improvements present in a CO₂ abated CFP plant results in a 15.1%–17.3% and 7.6%–8.0% decrease in capital and operational expenditure respectively for the CO₂ capture cases. …”

Beta-Glucans Supplementation Associates with Reduction in P-Cresyl Sulfate Levels and Improved Endothelial Vascular Reactivity in Healthy Individuals by Carmela Cosola (3687733)

“…</p><p>Methods</p><p>We carried out a pilot study on 26 healthy volunteers who underwent a 2-month dietary treatment including a daily administration of Granoro “Cuore Mio” pasta enriched with barley beta-glucans (3g/100g). …”

CX3CL1 (Fractalkine) Protein Expression in Normal and Degenerating Mouse Retina: <i>In Vivo</i> Studies by Marina Zieger (626340)

“…The immunoblots revealed that in both, wt and rd10 retinas, a membrane integrated ∼100 kDa CX3CL1 form and a cleaved ∼85 kDa CX3CL1 form were present at P5. …”

Isoform-specific Tutl overexpression differentially regulates dendrite branching in class II and III da neurons. by Mikolaj J. Sulkowski (177479)

“…Anterior is left and dorsal up and size bars represents 150 microns for ldaA and 100 microns for v'pda. (<b>A</b>) Wild-type (WT) ldaA neuron. …”

Image_2_Light intensity changes and UVB radiation affect peridinin content and antioxidant activity in the Cassiopea andromeda holobiont.jpeg by Holger Kühnhold (6499133)

“…Over the treatment time, Chl a and Per concentrations, measured as µg g⁻¹ jellyfish dry weight and pg microalgae-cell⁻¹, decreased sharply at higher PAR intensities (200 – 800 µmol photons m⁻² s⁻¹) compared to the control treatment (100 µmol photons m⁻² s⁻¹). …”

Image_1_Light intensity changes and UVB radiation affect peridinin content and antioxidant activity in the Cassiopea andromeda holobiont.jpeg by Holger Kühnhold (6499133)

“…Over the treatment time, Chl a and Per concentrations, measured as µg g⁻¹ jellyfish dry weight and pg microalgae-cell⁻¹, decreased sharply at higher PAR intensities (200 – 800 µmol photons m⁻² s⁻¹) compared to the control treatment (100 µmol photons m⁻² s⁻¹). …”

Transformation of skin fibroblasts into hematopoietic cells that engraft in NOD-Scid mice. by David M. Harris (216744)

“…Right panel: Morphological analysis of transfected skin fibroblasts cytospun onto glass slides and stained with Wright-Giemsa demonstrated typical hematologic cell characteristics: (a) cultured untreated skin fibroblasts (X 100 magnification); (b) immature myeloid and lymphoid blasts (insert shows TdT nuclear immunofluorescent staining). …”