Data_Sheet_2_Integrating Ligand and Target-Driven Based Virtual Screening Approaches With in vitro Human Cell Line Models and Time-Resolved Fluorescence Resonance Energy Transfer A... by Gurbet Tutumlu (8691720)

“…In the first approach, a molecular docking and filtering approach is used to rank compounds based on their docking scores and only a few top-ranked molecules are selected for further long (100-ns) molecular dynamics (MD) simulations and in vitro tests. …”

Cx43 immunostaining and quantitative analysis in the neuromuscular compartment of normal and diverticular disease human colon. by Letizia Mattii (302997)

“…<p>In normal colon, appreciable amounts of Cx43 are expressed in the circular (CM) and longitudinal muscle (LM) (A), while Cx43 expression is decreased in samples from DD colon (B); scale bar: 100 µm. …”

Figure 3 by Michael S. Akhras (60473)

“…<b>C</b>) DNA amounts were set at 100 ng for HPV-45 plasmid and 1 nanogram for HPV-59 plasmid, which was observed as a ∼3-fold decrease in signal intensity. …”

PAMs ameliorates the psoriasis-like symptoms and skin inflammation in imiquimod-induced mice. by Rongkun Dou (1887913)

“…<p>A: Histopathological investigation in each group (×100). …”

DataSheet_1_Analyzing the impacts of cadmium alone and in co-existence with polypropylene microplastics on wheat growth.docx by Zhiwei Han (9987860)

“…The co-occurrence of Cd and PP-MPs indicated that 50 μm PP-MPs+Cd had an antagonistic impact on wheat seedling growth, whereas 100 μm PP-MPs+Cd had a synergistic impact due to the larger size of PP-MPs. …”

Inhibitors of PI3K, AKT and rapamycin do not prevent apoptosis in wild-type EGFR-expressing cells treated with EGF. by Cezary Treda (517151)

Impairment of RPA foci formation and the DNA damage checkpoint in CBP and p300 depleted cells. by Hideaki Ogiwara (18358)

“…Chromatin enriched fractions from cells pre-transfected for 48 hr with non-targeting (siNT) or CBP+p300 (siC+p) siRNA were treated or not treated (NT) with (D) 500 ng/ml neocarzinostatin (NCS) for 1 or 2 hr, or (E) incubated for 3 hr after 50 Gy ionizing irradiation (IR) and subjected to immunoblot analysis. …”

Lin28 promotes adhesion and migration in breast cancer cells. by Yujie Liu (188278)

“…<p>A and B. Cell adherence assays revealed that Lin28 stably expressed MCF-7 clones pc-Lin28-1 and pc-Lin28-2 adhered better to the fibronectin-coated surface than empty vector and Lin28-mut transfectants (A). …”

Hierarchically clustered ANIm heatmap across Set-R combined with phylogenetic information reveals unknown species diversity within the ACB clade. by Bardya Djahanschiri (6203681)

“…These clusters and cutoffs are typically used for bacterial species delineation. In the ACB clade, we observe a large and distinct cluster with 98–100% sequence identity (rounded) for the <i>A</i>. …”

<i>In vitro</i> and <i>in vivo</i> properties of aminotriazines used in this study. by David J. Matson (625974)

“…<p>Shown for each compound are IC50 on non-inactivated human Nav1.7, IC50 on 20%-inactivated human Nav1.7, and IC50 on 20%-inactivated rat Nav1.7, all taken with patch-clamp electrophysiology; <i>in vitro</i> plasma protein binding; the ratio of brain to plasma concentrations <i>in vivo</i>; whether the compound produced analgesic efficacy in the rat formalin model of pain; and the plasma concentration corresponding to the lowest dose that produced efficacy. …”

TF function predicted from regulatory parameters <i>α</i> and <i>β</i>. by Md Zulfikar Ali (11965544)

“…Black contours mark FC_max = 1 and subsequent contours represent 100–fold increase or decrease in FC_max. …”

Deterministic sensitivity analysis. by Katharina Wahedi (7136459)

“…Bars on the right indicate an increase of ICER, bars on the left show a decrease of ICER. Changes resulting from increasing the parameters are represented by green bars while those resulting from a decrease of parameters are shown in red.…”

Astrocytes participate in the maintenance of epileptiform activity in CA1. by Guyllaume Coiret (323163)

“…<p>A, A field recording in the CA1 area and a patch-clamp recording from a CA1 pyramidal cell show a typical initial depolarization event followed by epileptiform discharge (ED) in response to continuous application of 4-AP (100 µM). …”

Resveratrol Protects Chondrocytes from Apoptosis via Altering the Ultrastructural and Biomechanical Properties: An AFM Study by Hua Jin (320594)

“…CCK-8 assay showed that 100 μM RV significantly prevented SNP-induced cytotoxicity. …”

Data set on the survival of <i>Anopheles coluzzii</i>. by Sié Hermann Pooda (9987061)

Table_1_Effect of COVID-19 vaccine on blood glucose metrics in Arabic people with type 1 diabetes.docx by Ebaa Al-Ozairi (5956982)

RECQL4 functions in a separate pathway from REV1 and is degraded following DNA crosslinks. by Thong T. Luong (13833935)

“…<p>(A) RECQL4 levels decrease following cisplatin treatment. U2OS cells were incubated with 50 μg/ml cycloheximide in the presence or absence of 50 μg/ml cisplatin. …”

Dynamics of the Ca²⁺ depletion waves. by Mitra Esfandiarei (280455)

“…<p><b>A)</b> Heat map generated from the time-lapse fluorescence microscopy movie (10 s intervals) of rat SMCs treated with ET-1 (100 nM) in nominally free extracellular Ca²⁺, showing that the SR depletion wave expands in a near circular fashion in both directions of the scan line (dotted white line). …”

Neosartorya glabra polygalacturonase produced from fruit peels as inducers has the potential for application in passion fruit and apple juices by Vanessa Elisa Pinheiro (10424390)

“…The aim of this work was to assess the production of polygalacturonase by the fungus Neosartorya glabra by means of solid-state and submerged fermentation using fruit peel residues as the carbon source, and also apply the enzyme in the clarification and decrease in viscosity of passion fruit and apple juices. …”

Inhibition assays for bispecific antibody. by Wei Wang (17594)