The complementary chimera IIS4I shifts the gating of Ca_V1.2 channels towards low-voltage behavior. by Ana Laura Sanchez-Sandoval (4885423)

“…For clarity purposes only the last 50 ms of the prepulses are shown. Note that chimeric channels availability decreases proportionally as the <i>V</i>_m become more positive, similar to the behavior of Ca_V3.3-WT channels (see <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0193490#pone.0193490.g004" target="_blank">Fig 4</a>). …”

Acute reduction of Ezh2 induces apoptosis in NSCs. by Falak Sher (151989)

“…Immunostaining of dissociated neurospheres in proliferation medium shows a decrease in proliferation and increase in cell death after using Ezh2-shRNA compared to the control (nc-shRNA). …”

Robustness to noise. by Martin Boerlin (355887)

“…Results are reported for percentual decreases in the signal-to-noise ratio, SNR = mean(input)/std(input), of 0% (black), 20% (blue), 50% (red) and 100% (green). …”

Sholl analysis and spine density analysis in mouse hippocampal neurons. by Qiang-qiang Xia (8060987)

“…WT N = 50/10 cells/mice; HET N = 50/10). *P<0.05, **P<0.01, ***P<0.001, unpaired student’s t-test; graphs depict mean ± SEM. …”

Long-term trends of potential years of life lost due to main causes of death in the Slovak population, 2004-2013 by Martin Samohyl (10388448)

“…The PYLL rate is age-standardized and expressed as a sum of all deaths per 100,000. In the period 2004-2013, the highest mean PYLL rates were observed in neoplasms in the whole population (2,103 per 100,000), as well as in females (2,088 per 100,000), with a permanent high significant increase of AAPC of PYLL in both genders. …”

HuR specifically represses translation through the IGF-IR 5′-UTR in a concentration-dependent manner by Zheng Meng (9293)

“…The IGFIR(1–1038)-FLuc RNA (5 ng) was incubated with increasing amounts of transcribed mRNA encoding HuR (5–50 ng) in an translation reaction (with RRL). …”

Cochlear hair cells are reduced in <i>Fgfr1</i> mutants. by Kazuya Ono (513633)

“…Cochlear length is decreased by approximately 40–50% in all <i>Fgfr1</i> mutants except <i>Fgfr1^Y766F/Y766F</i>. …”

The time-dependent currents in <i>Mytilus galloprovincialis</i> hemocytes are modulated by the osmotic pressure. by Monica Bregante (3391766)

“…D) The hyperosmotic bath solution determines a decrease of the steady-state current elicited by V = -100 mV (left bar) without altering the capacitance of the cells (right bar). …”

Supplementary Material for: Early Variation of Respiratory Indexes to Predict Death or ICU Admission in Severe Acute Respiratory Syndrome Coronavirus-2-Related Respiratory Failure by Maraziti G. (12243848)

“…<b><i>Results:</i></b> ROX <3.85 at admission (hazard ratio [HR] 2.95, 95% confidence interval [CI] 1.29–6.77) and decreasing RI or P/F during hospitalization (RI: HR 1.05, 95% CI: 1.00–1.09; P/F: HR 1.01, 95% CI: 1.00–1.02) were predictors of in-hospital death. …”

Marimastat reversed hepatic steatosis in diet-induced obese mice as well as in <i>ob/ob</i> animals, as demonstrated by histology and magnetic resonance spectroscopy. by Vincent E. de Meijer (343377)

“…Histological findings were confirmed with MRS, demonstrating a decrease in fat content in Marimastat-treated animals (A,B bottom panels).…”

Neurons are uncorrelated during PABA and exhibit Poisson-like irregularity. by Nigel Stepp (683934)

“…As the number of neurons increases, the average firing rate decreases. At sizes above 100,000 neurons, i.e. on the order of a small collection of cortical columns, firing rates drop to below 5 Hz, which is comparable to biological networks. …”

Table_1_Non-invasive Biomarkers of Liver Inflammation and Cell Death in Response to Alcohol Detoxification.DOCX by Manuela G. Neuman (11086812)

Induction of <i>ilys-3</i> requires ERK. by Maria João Gravato-Nobre (2941827)

“…Mean values for <i>mpk-1</i> mutants on CBX102 were not significantly different from their sibling controls on OP50 (<i>p</i> = 0.6098). …”

Impact of Global <i>Fxr</i> Deficiency on Experimental Acute Pancreatitis and Genetic Variation in the <i>FXR - Figure 2 </i> Locus in Human Acute Pancreatitis by Rian M. Nijmeijer (208613)

“…<p>A - Representative pancreatic histology following induction of acute pancreatitis (H&E staining, 20x and 100x consecutive magnifications for each experimental group): wild-type control (a,b); wild-type acute pancreatitis (c,d); Fxr^-/- control (e,f); Fxr^-/- acute pancreatitis (g,h). …”

The effects of thioperamide and alpha-FMH on the amount of sleep/wake in WT and W/W^v mice. by Sachiko Chikahisa (417256)

“…(B) In contrast, injection of alpha-FMH (ip), a HDC blocker, at medium (50 mg/kg) and high (100 mg/kg) doses decreased the amount of wakefulness in WT mice. …”

Table1_Retrospective Recall of Psychological Distress Experienced During the First COVID-19 Lockdown in Italy: Results From the ALT RISCOVID-19 Survey.doc by Francesca Bracone (12014342)

“…</p><p>Methods: Cross-sectional analysis on 1,880 adults (mean age 48.9 ± 14.5 years) from the web-based ALT RISCOVID-19 survey. …”

Nutritional profile of patients in a multidisciplinary treatment program for severe obesity and preoperative bariatric surgery by Fernanda Cristina Carvalho Mattos MAGNO (6380201)

“…RESULTS: From the total, 73% of the patients were women and 27% male, mean age was 48.4+12.9 and 49.8+8.1, respectively. …”

Predicted change in current financial strain between M2 (2004–05) and M3 (2013–14) by changes in assets. by Dana A. Glei (1939324)

“…The difference (M3—M2) in log assets is equivalent to the log of the ratio of assets at M3 relative to M2. Thus, a 0.7 decrease in log assets represents a loss of 50% (24% of the observed sample exhibited a loss of that magnitude or greater), whereas a 0.7 increase corresponds with an approximate doubling of assets (28% of the sample reported a gain of that magnitude or greater). …”

Relative expression of target genes normalized with different numbers of reference genes. by Daijun Ling (188975)

“…(B) The age-dependent increased <i>Hsp70</i> expression also shows minor decrease when normalized sequentially by 1, 3 or 13 reference genes. …”

FOXO3a down-regulates <i>PRNP</i> expression by binding to its promoter. by Ting Liu (45625)

“…All experiments were performed three to five times, and the data were analyzed as the mean ± S.E.M. (P<0.05).</p>…”