The attenuating effects of Msi1 knockdown on Hh signaling in MSC proliferation and apoptosis. by In-Sun Hong (284033)

“…Purmorphamine increased cell proliferation (<b>A</b>) and decreased TUNEL-positive cell numbers (<b>B</b>), while the 50 nM Msi1 siRNA transfection produced the opposite effects. …”

H3 K36 Methylation Helps Determine the Timing of Cdc45 Association with Replication Origins by Fiona Pryde (263331)

Cytoproliferative effect of low dose alpha radiation in human lung cancer cells is associated with connexin 43, caveolin-1, and survivin pathway by Vasumathy Rajan (6920285)

DataSheet_1_Treatment Interruptions During Stereotactic Body Radiotherapy for Prostate Cancer.docx by Abigail N. Pepin (11966438)

“…Median length of time to complete treatment was 11 days (range 5–155 days). In patients who experienced a delay, nearly half (45.5%) experienced only a one-day delay. …”

Cancer cell specific effect of the SB-based gene delivery system with the hTERT promoter on cell viability. by In-Sun Hong (284033)

“…<p>Cell viability was assessed using the MTT with or without transfection of the SB system (pT.hTp.HSV-tk.Con with active helper plasmid) following administration of 10, 30, or 50 µg/mL GCV at 3 day post-transfection. GCV alone had negligible effect on effect on the cell viability (A), whereas transfection of the SB system (pT.hTp.HSV-tk.Con with active helper plasmid) following administration of GCV significantly decreased the cancer cell viability in a dose-dependent manner (B). …”

Examination of known somatic cell B-Myb target gene expression patterns following knockdown of B-Myb in ESCs. by Ming Zhan (27937)

“…B) RNA (left) and protein (right) analysis of the B-MYB target gene Polo-like kinase 1 (Plk1) following Bγ-Myb KD with shRNA1 and shRNA5. The effects of B-MYB KD on Plk1 RNA were transient; however, the loss of RNA led to a significant and sustained decrease in its protein abundance. …”

Stability of beta-titanium T-loop springs preactivated by gradual curvature by Sergei Godeiro Fernandes Rabelo Caldas (4791744)

“…The other eight groups were tested after 24, 48 and 72 hours, 1, 2, 4, 8 and 12 weeks, respectively. Using a moment transducer coupled to a digital extensometer indicator adapted to a universal testing machine, the amount of horizontal force, moment and moment-to-force ratios were recorded at every 0.5 mm of deactivation from 5 mm of the initial activation, in an interbracket distance of 23 mm. …”

Image2_Arnica Montana L. Supercritical Extraction Optimization for Antibiotic and Anticancer Activity.JPEG by Taja Žitek (12521470)

“…The content of proanthocyanidins was highest at a pressure between 18 and 24 MPa. The extracts inhibited three different microorganisms successfully; Staphylococcus aureus, Escherichia coli and Candida albicans, at concentrations ranging from 0.1 to 5.16 mg/ml and showed anticancer activity decrease up to 85% at a concentration of 0.5 mg/ml.…”

Regulation of cardiac transcription factors in liver stem cells co-cultured with cardiomyocytes after minimizing CAMTA1 expression. by Barbara Muller-Borer (159061)

“…The graphs illustrate expression of the transcription factors CAMTA1, CAMTA2, Nk×2.5, Myocardin, cTnT and BetaMHC. A significant decrease in the expression of transcription factors Nkx2.5, Myocardin, cTnT and BetaMHC were measured when CAMTA1 expression was minimized. …”

Buffer Zones for 2,4-D Applications Nearby Tobacco Fields by Matheus Machado Noguera (13022509)

“…Drifted herbicide was collected using tobacco plants placed at various points (-50 up to 400 meters from application zone), following three schemes: a) 0 to 0.5 hours after application (HAT); b) 0 to 24 HAT; and c) 0.5 to 24 HAT. …”

Image1_Arnica Montana L. Supercritical Extraction Optimization for Antibiotic and Anticancer Activity.JPEG by Taja Žitek (12521470)

“…The content of proanthocyanidins was highest at a pressure between 18 and 24 MPa. The extracts inhibited three different microorganisms successfully; Staphylococcus aureus, Escherichia coli and Candida albicans, at concentrations ranging from 0.1 to 5.16 mg/ml and showed anticancer activity decrease up to 85% at a concentration of 0.5 mg/ml.…”

Evaluation of paralysis time and animal behavior in the open field. by Sunamita de Carvalho Lima (5598089)

“…The last bar in panel A, indicated by the 24 h in the open box, refers to the <i>ip</i> administration of same dose of crotamine (7.5 μg/animal or 0.3 mg/kg BW) in the same animal 24 h after first crotamine administration, showing a significant decrease in the time for paralysis onset compared to the first administration of crotamine in naïve animal, a day before. …”

Systemic status of WT and miR-150 null mutant (miR-150^-/-) mice with normal chow diet or HFD. by Liheng Shi (144105)

“…There is no statistical interaction between miR-150 null mutation and HFD regimen (2-way ANOVA). n = 5 for each group. (C) Wild type mice fed with HFD have a significant decrease of miR-150 expression compared to mice fed with normal diet (Normal; student’s <i>t</i>-test). …”

Non-parametric regression of the number of basic cognitive units (BCU) on age. by Raúl de la Fuente-Fernández (42989)

“…</p> <p>Data points were directly derived from the <i>z</i>-scores associated with the corresponding Alzheimer's incidence rates, using the equation: BCU|age = 0.5−0.1× <i>z</i>-score, where the threshold (<i>c</i>) is 0.5, and the standard deviation (SD) is 0.1 (see <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0000052#s2" target="_blank">Methods</a>).…”

Conditional knockout of <i>Ezh2</i> gene in murine hearts caused perinatal lethality. by Li Chen (5749)

“…Semi-quantitative RT-PCR with two different numbers of amplification cycles (30 and 35) was performed on RNA samples purified from WT hearts of E9.5, E10.5, and E11.5. 1 µl or 0.5 µl cDNA from reverse transcription reaction was used for detection of Ezh2 or GAPDH (as a control), respectively. …”

hTTR levels in serum and stomach. by Elena Panayiotou (3925415)

“…<p>hTTR immunoblotting exhibiting a single band at 14KDa (<i>A</i>). hTTR levels measured via immunoblotting in serum of V30M and V30M C1q KO animals of all three age groups indicating higher hTTR in the V30M mice and a gradual decrease in the amount of hTTR present as the animals age (<i>B</i>). hTTR levels measured via immunoblotting in stomach tissue of the V30M and V30M C1q KO animals exhibit a severe decrease in the second age group (<i>C</i>). …”

Loss of the macrophage-TCR in the presence of functional T cells results in disorganized granulomas and CCL2 suppression in murine pulmonary tuberculosis. by Alexander W. Beham (196299)

“…<p>(<b>A</b>) TNF blockade decreases the number and size of macrophage clusters induced by <i>BCG</i> infection <i>in vitro</i>. …”

T-helper cell pathway diagram. by Josephine S. D’Alessandro (814578)

“…Gray lines indicate members of a group. APCs, antigen-presenting cells; CXCR1, chemokine (C-X-C motif) receptor 1; CXCR3, chemokine (C-X-C motif) receptor 3; CXCR5, chemokine (C-X-C motif) receptor 5; CXCL10, chemokine (C-X-C motif) ligand 10; GA, glatiramer acetate; HLADMA, major histocompatibility complex class II, DM alpha; HLADMB, major histocompatibility complex class II, DM beta; HLADQB1, major histocompatibility complex class II, DQ beta 1; ICOSLG, inducible T-cell costimulatory ligand; IL-4, interleukin-4; MHC class II, major histocompatibility complex class II; LTB, lymphotoxin beta (tumor necrosis factor superfamily, member 3); MYD, myeloid differentiation primary response protein; S100A10, S100 calcium-binding protein A10; STAT, signal transducer and activator of transcription; TCR, T-cell receptor; Th, T-helper.…”

Age-related epigenome-wide DNA methylation and hydroxymethylation in longitudinal mouse blood by Joseph Kochmanski (5597024)

“…We tested the hypothesis that 5hmC changes with age, but in a direction opposite to 5-methylcytosine (5mC), potentially playing a distinct role in aging. …”

Fig 2 - by G. Cennamo (11785349)

“…The patient shows a focal reduction in GCC and RNFL (B4, B5) at baseline, a slight decrease in GCC (C4) and an absence of changes in RNFL (C5) at 48 hours after surgery. …”