Injection of rIL-6 in IL-6KO mice decreased chronic disease severity following CB3/LPS treatment. by Maya C. Poffenberger (262165)

“…(B) Chronic cardiac disease histology was scored blindly by a four tier grading system to determine severity differences: grade 1, 0–10% pathology; grade 2, 11–25%; grade 3, 26–50%; grade 4, greater than 50% (black circles indicate wt mice with DMEM, white circles indicate IL-6KO mice with DMEM, grey circles indicate IL-6KO mice with rIL-6) (bar is mean±SE, *p<0.05). …”

First-in-Class Hydrazide-Based HDAC6 Selective Inhibitor with Potent Oral Anti-Inflammatory Activity by Attenuating NLRP3 Inflammasome Activation by Kairui Yue (11874403)

“…Representative inhibitor <b>35m</b> exhibits potent HDAC6 inhibitory activity with an IC₅₀ value of 0.019 μM. To our surprise, <b>35m</b> establishes significant improvement in the pharmacokinetic property with much higher AUC_0‑inf (10292 ng·h/mL) and oral bioavailability (93.4%) than hydroximic acid-based HDAC6 inhibitors Tubastatin A and ACY-1215. …”

First-in-Class Hydrazide-Based HDAC6 Selective Inhibitor with Potent Oral Anti-Inflammatory Activity by Attenuating NLRP3 Inflammasome Activation by Kairui Yue (11874403)

“…Representative inhibitor <b>35m</b> exhibits potent HDAC6 inhibitory activity with an IC₅₀ value of 0.019 μM. To our surprise, <b>35m</b> establishes significant improvement in the pharmacokinetic property with much higher AUC_0‑inf (10292 ng·h/mL) and oral bioavailability (93.4%) than hydroximic acid-based HDAC6 inhibitors Tubastatin A and ACY-1215. …”

The human neutrophil IL-1β secretory response, in contrast to the CXCL8/IL-8 secretory response decreases as MOI increases. by Florencia Sabbione (4862455)

Leptin Decreases MAFbx and MuRF1 Protein Expression in Gastrocnemius Muscle of Wild Type and <i>ob/ob</i> Mice. by Neira Sáinz (260167)

[Na⁺]_i is decreased in SLO3 mutant sperm and in sperm treated with the SLO3 inhibitor clofilium. by Julio C. Chávez (399841)

Antagonism of ghrelin receptors resulted in decreased reward and delayed reductions of EtOH-motivated behaviors with an overall increased sensitivity in RYGB rats. by Andras Hajnal (299955)

Decreased vessel number and increased vessel caliber in <i>Fzd4</i>^+/- mice after ocular ischemic retinopathy. by Michael H. Ngo (3143202)

The Activation Effects of Low Level Isopropyl Alcohol Exposure on Arterial Blood Pressures Are Associated with Decreased 5-Hydroxyindole Acetic Acid in Urine by Zhiqiang Zhao (201543)

Mesothelin expression and RG7787 uptake is decreased in KLM-1-R. by Kevin Hollevoet (710450)

Decreased levels of NMDAR2B in the synaptic plasma membrane of spinal cord of CCI-mice treated with compound 30 at 56 dpi. by Xavier Xifró (719821)

Adiponectin reduces neutrophil phagocytosis by decreasing the phosphorylation of PKB and ERK 1/2 but not p38 in response to <i>E. coli</i>. by Alessandra Rossi (8710)

Predicted cylindrical cavity pressure as a function of saturation for two clay contents (16 and 50%) and for a range of cavity radii (1 to 5 mm). by Siul Ruiz (757454)

Leishmanization with <i>L</i>. <i>major</i> + Pam3CSK4 decreases lesion size and parasite burden in mice. by Lu Huang (211625)

siRNA-mediated APP-BP1 knock-down significantly decreases BrdU-incorporated fetal neural stem cells. by Yuyoung Joo (236048)

Gender differences in what subjects students report they might find offensive if an instructor of a college science course were to tell a joke about them. by Katelyn M. Cooper (5634851)

Gender differences in what subjects students report they might find funny if an instructor of a college science course were to tell a joke about them. by Katelyn M. Cooper (5634851)

Presentation_1_Airway macrophages display decreased expression of receptors mediating and regulating scavenging in early cystic fibrosis lung disease.pdf by Lisa J. M. Slimmen (16464600)

“…The effect of age and neutrophilic inflammation, among other variables, on marker expression was assessed with a multivariate linear regression model.</p>Results<p>AM expression of scavenger receptor CD163 decreased with age (p = 0.016) and was negatively correlated with BALF %neutrophils (r = -0.34, p = 0.016). …”

Helminth co-infection results in decreased number of CD11b⁺ cells and antimicrobial peptide expression in colonic tissue. by Libo Su (596288)

Multinomial logistic model of the effects of a cluster of phenolic compounds on host and parasitoid survival across development among larvae that survived to at least 50 mg. by Noah H. Rose (703745)