Combination therapy of Euphorbia kansui and SAHA or JQ1 reactivates latent HIV and activates T cells. by Daniele C. Cary (3559394)

“…At 12 days post infection, cells were stimulated for 24 hours with DMSO, PMA (2 μg/ml) and PHA (10 ng/ml), IngDB (50 ng/ml), Euphorbia kansui (50 μg/ml), Euphorbia kansui (50 μg/ml) and SAHA (0.5 μM), or Euphorbia kansui (50 μg/ml) and JQ1 (0.1μM). …”

NF-κβ, COX, and ROS involvement in EP bridge formation. by Brett G. Zani (254541)

“…SC-514 (100 µM), an NF-κβ inhibitor, decreased secretion of all three proteins after 48 h in EPs/ECs and EPs/FBs. …”

Experiment 1: Rapid-Place Learning Task and Performance after Partial Hippocampal Lesions Sparing the Intermediate, Septal, or Temporal Hippocampus by Tobias Bast (264973)

“…</p> <p>(D and E) Postsurgical performance: (D) percentage time (%time) in correct zone (mean ± SEM) on probes and (E) path lengths (mean ± SEM) to reach the platform on T1–T4, as well as path-length reductions from T1 to T2 (savings, inset graph) in sham-lesioned rats, in rats with approximately 40% of residual hippocampal volume in the intermediate, temporal, or septal hippocampus, and in rats with complete hippocampal lesions (compare <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.1000089#pbio-1000089-g001" target="_blank">Figure 1</a>B and <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.1000089#pbio-1000089-g001" target="_blank">1</a>C). …”

Renal NF-kB protein expression in FA induced injury in mice. by Dev Kumar (681481)

“…<p>Representative images of NF-kB immunostaining (green: FITC and red: Propidium iodide) showing decrease in protein expression in PDTC treated mouse kidney at 48 hr after FA treatment (A–L). n = 4; Magnification: 40X, 100X, and 400X with scale bar: 100 µm, 100 µm and 50 µm respectively.…”

Renal p53 expression in FA induced injury in mice. by Dev Kumar (681481)

“…<p>Representative images of p53 immunostaining (green: FITC and red: Propidium iodide) showing decrease in protein expression in PDTC treated mouse kidney at 48 hr after FA treatment (A–L). n = 4; Magnification: 40X, 100X, and 400X with scale bar: 100 µm, 100 µm and 50 µm respectively.…”

Contribution of JNK isoforms to TNF-α-induced IL-8 expression. by Shinichi Namba (3350288)

“…<p>(A) Expression of phosphorylated JNK1/2 (p-JNK1/2) and total JNK1/2 (t-JNK1/2) was detected by western blotting in cells treated with TNF-α (50 ng/mL) for 0–120 min (upper panel). Time-dependent change of relative density of p-JNK compared with that at time 0 is described (lower panel). …”

The relative expression level of 10 larval stage specific genes and the larval mortality. by Yubing Wang (225033)

“…(<b>C</b>) The larval mortality of dsRNA directly sprayed on the larvae which were placed on filter paper. 50 ng/µl dsRNA of DS10 and DS28 were directly sprayed on the newly hatched larvae on a filter paper pre-soaked in the buffer, and then the larvae were transferred to artificial diet. …”

Figure 3 by Michael S. Akhras (60473)

“…<b>C</b>) DNA amounts were set at 100 ng for HPV-45 plasmid and 1 nanogram for HPV-59 plasmid, which was observed as a ∼3-fold decrease in signal intensity. …”

Supplementary Material for: Stroke Prevalence, Mortality and Disability-Adjusted Life Years in Children and Youth Aged 0-19 Years: Data from the Global and Regional Burden of Strok... by Krishnamurthi R.V. (3236010)

“…While prevalence rates for childhood IS and HS decreased significantly in developed countries, a decline was seen only in HS, with no change in prevalence rates of IS, in developing countries. …”

The Influence of Doctor-Patient and Midwife-Patient Relationship in Quality Care Perception of Italian Pregnant Women: An Exploratory Study by Laura Andrissi (729056)

“…The perceived quality of welcome scaled with a decreased need of additional care and, more in general, with a more faithful attitude towards health professionals. …”

Inhibitors of PI3K, AKT and rapamycin do not prevent apoptosis in wild-type EGFR-expressing cells treated with EGF. by Cezary Treda (517151)

Deterministic sensitivity analysis. by Katharina Wahedi (7136459)

“…Bars on the right indicate an increase of ICER, bars on the left show a decrease of ICER. Changes resulting from increasing the parameters are represented by green bars while those resulting from a decrease of parameters are shown in red.…”

Characterisation of stimulating rat anti-β1EC2. by Valérie Boivin (694135)

“…<p>(A) ELISA-reactivity (mean±SEM) of n = 6 representative rat anti- β₁EC2 (1:5000, 12h, 4°C) with linear (dark green) or cyclic β₁EC2-peptides (light green); <i>p</i><0.005 (Student’s t-test). …”

Resveratrol Protects Chondrocytes from Apoptosis via Altering the Ultrastructural and Biomechanical Properties: An AFM Study by Hua Jin (320594)

“…CCK-8 assay showed that 100 μM RV significantly prevented SNP-induced cytotoxicity. …”

Characterization of LNCaP cell growth cultured within biomimetic hydrogels in normal growth media, RPMI and 10% FBS. by Shirly Sieh (139080)

“…<p>(A) Growth curves of LNCaP cells over 7 days for 2D cultures (left) and 28 days for 3D cultures (right) in normal growth media measured by total DNA content (mean ± SE). …”

Selectivity of PRMT5 inhibition with C220. by Shelby L. Sloan (10803222)

“…For all cell lines, effects of PRMT5 inhibition with C220 treatment on biomarkers of PRMT5 activity shows a dose-dependent decrease in global marks of symmetric di-methylarginine (SDMA) and symmetric di-methylation of histone H4 arginine-3 (H4R3me2s) with a minimal effect to PRMT5 or global asymmetric di-methylarginine (ADMA). …”

Inhibition assays for bispecific antibody. by Wei Wang (17594)

HIV-1 envelope glycoprotein gp41 schematic and structure of the 2F5 antibody-peptide complex. by Javier Guenaga (150719)

“…Residues at the apex of the CDRH3 in magenta (_100ALFGV_100D) were not altered. …”

Mitochondrial Ca²⁺ uptake in permeabilized H295R cells transfected with <i>OPA1</i> or <i>Mfn1</i> siRNA. by László Fülöp (203208)

“…On day 5 the cells were permeabilized, superfused with a cytosol-like medium, Ψ_m was dissipated with 10 µM rotenon, 8 µg/ml oligomycin, 10 µM FCCP and 50 ng/ml valinomycin for 2 minutes. Then, in the presence of the drugs, [Ca²⁺] was raised from 0 to 5 µM. …”

Supplementary Material for: Tacrolimus Suppositories in Therapy-Resistant Ulcerative Proctitis by Jaeger S.U. (5947727)

“…A decrease in CAI (from 8.0 to 5.5 points) was observed and 52.3% reached clinical remission (CAI ≤4). …”