Wound closure assay shows defect in polarized cell movement in Cx43 KO MEFs. by Richard Francis (201117)

“…There was also a marked decrease in the directionality and speed of wound closure (F). …”

ITC-derived binding affinity may be biased due to titrant (nano)-aggregation. Binding of halogenated benzotriazoles to the catalytic domain of human protein kinase CK2 - Fig 4 by Maria Winiewska (3821416)

“…<p><b>DLS-derived autocorrelation function (ACF) measured for the decreasing concentration of 5-BrBt (A) and TBBt (B).…”

Statistical comparisons for the joint entropy measurements obtained from individual subjectspresented in Tables 1–3. by Vladímir de Aquino Silveira (513285)

“…In all frequencies there was a trend for joint entropy to decrease when contrast was increased, but this reached the level of statistical significance only for the comparison between 5% and 100% contrasts (p<0.05; One-Way ANOVA, Tukey Multiple Comparison Test). …”

Percent change in production and consumption sustainability for the top 25 seafood producing countries (according to FAO data). by Kayla M. Blincow (20370884)

“…The nature of this equation means that positive percent change values occur for countries that have a decrease in consumption sustainability compared to production sustainability and negative values occur for countries that have an increase.…”

DataSheet1_SGLT2 inhibitors suppress epithelial–mesenchymal transition in podocytes under diabetic conditions via downregulating the IGF1R/PI3K pathway.zip by Ruixue Guo (6377939)

“…Additionally, SGLT2, IGF1R, phosphorylated PI3K, α-SMA, SNAI-1, and ZEB2 protein levels were increased in high glucose-stimulated human podocytes (HPC) and significantly decreased in dapagliflozin-treated (50 nM and 100 nM) or OSI-906-treated (inhibitor of IGF1R, 60 nM) groups. …”

Image4_SGLT2 inhibitors suppress epithelial–mesenchymal transition in podocytes under diabetic conditions via downregulating the IGF1R/PI3K pathway.TIF by Ruixue Guo (6377939)

“…Additionally, SGLT2, IGF1R, phosphorylated PI3K, α-SMA, SNAI-1, and ZEB2 protein levels were increased in high glucose-stimulated human podocytes (HPC) and significantly decreased in dapagliflozin-treated (50 nM and 100 nM) or OSI-906-treated (inhibitor of IGF1R, 60 nM) groups. …”

Image3_SGLT2 inhibitors suppress epithelial–mesenchymal transition in podocytes under diabetic conditions via downregulating the IGF1R/PI3K pathway.JPEG by Ruixue Guo (6377939)

“…Additionally, SGLT2, IGF1R, phosphorylated PI3K, α-SMA, SNAI-1, and ZEB2 protein levels were increased in high glucose-stimulated human podocytes (HPC) and significantly decreased in dapagliflozin-treated (50 nM and 100 nM) or OSI-906-treated (inhibitor of IGF1R, 60 nM) groups. …”

Image6_SGLT2 inhibitors suppress epithelial–mesenchymal transition in podocytes under diabetic conditions via downregulating the IGF1R/PI3K pathway.TIF by Ruixue Guo (6377939)

“…Additionally, SGLT2, IGF1R, phosphorylated PI3K, α-SMA, SNAI-1, and ZEB2 protein levels were increased in high glucose-stimulated human podocytes (HPC) and significantly decreased in dapagliflozin-treated (50 nM and 100 nM) or OSI-906-treated (inhibitor of IGF1R, 60 nM) groups. …”

Image8_SGLT2 inhibitors suppress epithelial–mesenchymal transition in podocytes under diabetic conditions via downregulating the IGF1R/PI3K pathway.TIF by Ruixue Guo (6377939)

“…Additionally, SGLT2, IGF1R, phosphorylated PI3K, α-SMA, SNAI-1, and ZEB2 protein levels were increased in high glucose-stimulated human podocytes (HPC) and significantly decreased in dapagliflozin-treated (50 nM and 100 nM) or OSI-906-treated (inhibitor of IGF1R, 60 nM) groups. …”

Image9_SGLT2 inhibitors suppress epithelial–mesenchymal transition in podocytes under diabetic conditions via downregulating the IGF1R/PI3K pathway.TIF by Ruixue Guo (6377939)

“…Additionally, SGLT2, IGF1R, phosphorylated PI3K, α-SMA, SNAI-1, and ZEB2 protein levels were increased in high glucose-stimulated human podocytes (HPC) and significantly decreased in dapagliflozin-treated (50 nM and 100 nM) or OSI-906-treated (inhibitor of IGF1R, 60 nM) groups. …”

Image5_SGLT2 inhibitors suppress epithelial–mesenchymal transition in podocytes under diabetic conditions via downregulating the IGF1R/PI3K pathway.TIF by Ruixue Guo (6377939)

“…Additionally, SGLT2, IGF1R, phosphorylated PI3K, α-SMA, SNAI-1, and ZEB2 protein levels were increased in high glucose-stimulated human podocytes (HPC) and significantly decreased in dapagliflozin-treated (50 nM and 100 nM) or OSI-906-treated (inhibitor of IGF1R, 60 nM) groups. …”

Image7_SGLT2 inhibitors suppress epithelial–mesenchymal transition in podocytes under diabetic conditions via downregulating the IGF1R/PI3K pathway.TIF by Ruixue Guo (6377939)

“…Additionally, SGLT2, IGF1R, phosphorylated PI3K, α-SMA, SNAI-1, and ZEB2 protein levels were increased in high glucose-stimulated human podocytes (HPC) and significantly decreased in dapagliflozin-treated (50 nM and 100 nM) or OSI-906-treated (inhibitor of IGF1R, 60 nM) groups. …”

Image11_SGLT2 inhibitors suppress epithelial–mesenchymal transition in podocytes under diabetic conditions via downregulating the IGF1R/PI3K pathway.TIF by Ruixue Guo (6377939)

“…Additionally, SGLT2, IGF1R, phosphorylated PI3K, α-SMA, SNAI-1, and ZEB2 protein levels were increased in high glucose-stimulated human podocytes (HPC) and significantly decreased in dapagliflozin-treated (50 nM and 100 nM) or OSI-906-treated (inhibitor of IGF1R, 60 nM) groups. …”

Image10_SGLT2 inhibitors suppress epithelial–mesenchymal transition in podocytes under diabetic conditions via downregulating the IGF1R/PI3K pathway.TIF by Ruixue Guo (6377939)

“…Additionally, SGLT2, IGF1R, phosphorylated PI3K, α-SMA, SNAI-1, and ZEB2 protein levels were increased in high glucose-stimulated human podocytes (HPC) and significantly decreased in dapagliflozin-treated (50 nM and 100 nM) or OSI-906-treated (inhibitor of IGF1R, 60 nM) groups. …”

Anchusa italica extract: phytochemical and neuroprotective evaluation on global cerebral ischemia and reperfusion by Akram Torki (5383154)

“…Induction of ischemia/reperfusion caused a decrease in the antioxidant capacity of the brain and serum as well as an increase in the malondialdehyde of the brain and serum. …”

Unadjusted associations between demographic characteristics and rate of influenza-like illness among subjects who were ILI free at baseline (N = 938). by Allison E. Aiello (155642)

“…</p>b<p>Variables added to the final adjusted model if the magnitude of effect was more than a 10% increase or decrease from the null value (RR = 1.00).…”

Fig 1 - by Aamir Raina (12870158)

“…<p>a: Seed germination in control; b: Progressive decrease in seed germination with increased mutagen concentration from 100 Gy to 400 Gy gamma rays in var. …”

Effect of ELAP fractions on apoptotic markers in HepG2 cells. by Daleya Abdulaziz Bardi (560119)

“…Isolated fractions caused a marked elevation in cytochrome <i>c</i> release and cell membrane permeability, and a noticeable decrease in MMP. …”

Comparison of tuned response amplitude with the same contrast in mixed and in constant contrast blocks. by Lionel G. Nowak (373941)

“…Relative to 100%, the distribution for high contrast is shifted to the left, indicating that response amplitude was larger for high contrast when neurons were adapted to a mixture of contrasts, compared to when neurons were adapted to the high contrast. …”

miR-9 directly interacted with the putative binding sites in the 3′-UTR of cyclin D1 and Ets1. by Liduan Zheng (182440)

“…The symbols (* and #) indicate a significant decrease and a significant increase from mock or anti-NC, respectively.…”