Effects of the mutant L29Q cTnC and SD cTnI determined by Molecular Dynamics simulations. by Alison Y. Li (486146)

“…The Ca²⁺ ion bound in site II is shown as a black sphere. (C) shows the largest movement caused by the L29Q mutation in the presence of the pseudo-phosphorylated cTnI, which is the re-orientation of helix A and helix B of cNTnC accompanied by a decrease of interhelical angle of 13°.…”

Small-diameter sensory neurons from mutant mice have relatively few deficits in chemical activation. by Katherine J. Zappia (3178827)

“…<p>(<b>A</b>) Calcium imaging of small-diameter DRG neurons revealed no difference in the percentage of neurons responding to the 100 μM of the TRPA1 agonist, cinnamaldehyde, when comparing control and mutant neurons. …”

Image_1_Compound small peptide of Chinese medicine alleviates cyclophosphamide induced immunosuppression in mice by Th17/Treg and jejunum intestinal flora.JPEG by Yuqing Cui (1529068)

“…<p>The aim of this study was to explore the efficacy of Compound small peptide of Chinese medicine (CSPCM) on cyclophosphamide (CTX) induced immunosuppression in mice. The 100 male Kunming mice were divided into 5 groups: group A (control group), group B (model group), group C (100 mg/kg.bw CSPCM), group D (200 mg/kg.bw CSPCM) and group E (400 mg/kg.bw CSPCM). …”

Relationship between functional disability and costs one and two years post stroke by Ingrid Lekander (3910180)

“…</p><p>Method</p><p>Resource use during first and second year following a stroke was estimated based on a research database containing linked data from several registries. …”

GPR39-expressing cells. by Fanning Zeng (124301)

“…Shown are ratiometric images of Ca²⁺ signals before and after 100 µM Zn²⁺ challenge. [Ca²⁺]<i>_i</i> is indicated on a rainbow scale with blue representing low [Ca²⁺]<i>_i</i> and orange/red high [Ca²⁺]<i>_i</i>. …”

Electrophoretic mobility shift assay showing the interaction of wild type TsTBP1 with Ts2-CysPrx TATA-box probe. by Oscar Rodríguez-Lima (821378)

“…B) The densitometric analysis shows a decrease on the intensity of shifted bands in homologous and heterologous competition. …”

Electrophoretic mobility shift assay showing the interaction of wild type TsTBP1 pAT5 TATA-box probe. by Oscar Rodríguez-Lima (821378)

“…B) Densitometric analysis shows a decrease on the intensity of shifted bands in homologous and heterologous competition. …”

Chronic high frequency deep brain stimulation of the nucleus accumbens drives time dependent changes in functional connectivity in the rodent limbic system by Samuel Ewing (100763)

“…Stimulation was delivered bilaterally with 100 μs duration constant current pulses at a frequency of 130 Hz delivered at an amplitude of 100 μA using a custom-made stimulation device. …”

Supplementary Material for: Burden of Neurological disorders in children and adolescents (<20 years old) in North Africa and the Middle East (NAME) from 1990 to 2021 by figshare admin karger (2628495)

“…Idiopathic epilepsy remained a leading cause of mortality, although it had a decrease of -50.9% in YLLs compared to 1990. …”

Healthy control group HR and CBF changes. by Liuchuang Wei (19273099)

“…Computational results revealed that hypovolemia reduces cerebral blood flow by approximately 100 mL/min due to a 30% decrease in blood volume, while vascular dysfunction—marked by a 50–100% increase in arterial stiffness—further diminishes cardiac output and cerebral perfusion. …”

Stromal cells enhance HOS-CSC migration via IL-6 and the expression of adhesion molecules. by Margherita Cortini (3350189)

“…The RNA from CSC was then extracted and analyzed for the MET expression that shows a dramatic decrease in the absence of IL-6 (*p<0.05).…”

Image_2_Compound small peptide of Chinese medicine alleviates cyclophosphamide induced immunosuppression in mice by Th17/Treg and jejunum intestinal flora.JPEG by Yuqing Cui (1529068)

“…<p>The aim of this study was to explore the efficacy of Compound small peptide of Chinese medicine (CSPCM) on cyclophosphamide (CTX) induced immunosuppression in mice. The 100 male Kunming mice were divided into 5 groups: group A (control group), group B (model group), group C (100 mg/kg.bw CSPCM), group D (200 mg/kg.bw CSPCM) and group E (400 mg/kg.bw CSPCM). …”

List of abbreviations used in this paper. by Liuchuang Wei (19273099)

“…Computational results revealed that hypovolemia reduces cerebral blood flow by approximately 100 mL/min due to a 30% decrease in blood volume, while vascular dysfunction—marked by a 50–100% increase in arterial stiffness—further diminishes cardiac output and cerebral perfusion. …”

Estimation of the CO and CBF. by Liuchuang Wei (19273099)

“…Computational results revealed that hypovolemia reduces cerebral blood flow by approximately 100 mL/min due to a 30% decrease in blood volume, while vascular dysfunction—marked by a 50–100% increase in arterial stiffness—further diminishes cardiac output and cerebral perfusion. …”

DataSheet_1_Safety, tolerability, pharmacokinetics and pharmacokinetic-pharmacodynamic modeling of cetagliptin in patients with type 2 diabetes mellitus.docx by Chen Zhou (466781)

“…Compared with placebo group, plasma active GLP-1 AUEC_0-24h increased by 2.20- and 3.36-fold in the 50 mg and 100 mg cetagliptin groups. A decrease of plasma glucose and increase of insulin and C-peptide were observed following OGTT in cetagliptin groups. …”

The involvement of trimolecular complex components in the process of tumor cell transendothelial migration. by Evelyn B. Voura (475793)

“…(E) Recombinant furin convertase (rFurin; 71 U/mL) stimulated transendothelial migration of MDA-MB231 (gray bar) and WM239 (white bars) cells at 3 hours. Increasing amounts of a furin inhibiting peptide decreased WM239 transendothelial migration. …”

At clinically relevant concentrations the anaesthetic/amnesic thiopental but not the anticonvulsant phenobarbital interferes with hippocampal sharp wave-ripple complexes-2 by Costas Papatheodoropoulos (78587)

“…The cross-correlation plot from another slice (b) illustrates the large decrease of function value during drug application at 100 μM. …”

Image_1_DALY trend and predictive analysis of COPD in China and its provinces: Findings from the global burden of disease study.tif by Mimi Zhai (13232313)

“…The ASR of DALY was 1445.53 per 100,000 people in 2017 and demonstrated a significant decrease. …”

Image_2_DALY trend and predictive analysis of COPD in China and its provinces: Findings from the global burden of disease study.tif by Mimi Zhai (13232313)

“…The ASR of DALY was 1445.53 per 100,000 people in 2017 and demonstrated a significant decrease. …”

DataSheet_1_Hyperinsulinemia impairs the metabolic switch to ketone body utilization in proximal renal tubular epithelial cells under energy crisis via the inhibition of the SIRT3/... by Jinlan Xie (12917417)

“…The addition of 2 mmol/l BHB improved ATP production, mitochondrial biosynthesis, and endocytic albumin function, while cell apoptosis was reduced in HK2 cells. The addition of 50 ng/ml insulin resulted in the decreased expression of SMCT1 along with an impaired mitochondrial function, decreased ATP production, and increased apoptosis. …”