Comparison of mutp53 binding to scDNA and linDNA by EMSA. by Marie Brázdová (394463)

“…<p>Mutp53 proteins R175H, G245S, R248W, R249S, R273H, R273C, R282W and wtp53 were bound to scDNA (pBSK, 200 ng, A), linDNA (linBSK, 200 ng, B) and to linDNA with p53CON sequence (linPGM1, 200 ng, C) in p53/DNA molar ratios 1, 2, 3 and 5 (for R175H only) at 25°C; EMSA was performed at 4°C. …”

Image_1_Flavonoid Derivative of Cannabis Demonstrates Therapeutic Potential in Preclinical Models of Metastatic Pancreatic Cancer.JPEG by Michele Moreau (5726120)

“…<p>Pancreatic cancer is particularly refractory to modern therapies, with a 5-year survival rate for patients at a dismal 8%. …”

Effects of p-ERK1/2 and p-p38MAPK inhibitors on TNFα-induced occludin expression in hCMEC/D3 cells. by Yawen Ni (3723304)

“…Results are mean ± SD from 5 or more experiments. Two-way ANOVA revealed a significant main effect of TNFα (p<0.0001) and the inhibitors (p = 0.0287). …”

Zooming in: Structural Investigations of Rheologically Characterized Hydrogen-Bonded Low-Methoxyl Pectin Networks by Bradley W. Mansel (1514149)

Frequency dependent increase in contractile response of isolated detrusor strips in response to trains of 20 pulses at frequencies ranging from 0.25 to 40 Hz in the absence or in t... by Sara Pritchard (4030679)

“…<p>In detrusor strips from drug naïve animals, atropine significantly inhibited peak contractile responses at frequencies above 20 Hz (a). In strips from MPTP-treated animals (b), atropine did not significantly decrease peak contractions. …”

Image_2_Flavonoid Derivative of Cannabis Demonstrates Therapeutic Potential in Preclinical Models of Metastatic Pancreatic Cancer.png by Michele Moreau (5726120)

“…<p>Pancreatic cancer is particularly refractory to modern therapies, with a 5-year survival rate for patients at a dismal 8%. …”

Incidence of stalk rots in corn hybrids influenced by sowing time and nitrogen rates by Juliano Berghetti (6515036)

“…A decrease in the incidence of stalk rot was observed in the hybrid AG9025 PRO3 as nitrogen rates increased, but this behavior was not clearly observed in the hybrid 30F53 VYH.…”

Chronic intermittent ethanol (CIE) exposure alters the time course of STDP. by Sven Kroener (321008)

“…<p>EPSPs were induced by focal stimulation close to basal dendrites of the recorded neuron in layers V/VI. Pairing an EPSP with a burst of postsynaptic action potentials lead to consistent increases in all 3 treatment groups (control, CIE no withdrawal, and CIE followed by 7 days of withdrawal) at 20–30 minutes post pairing. …”

Effect of Dapagliflozin on Renal and Hepatic Glucose Kinetics in T2DM and NGT Subjects by Xi Chen (35903)

“…Following DAPA, EGP increased in both T2D and NGT from baseline to 240 minutes, while there was a significant time-related decrease after placebo in T2D. …”

Effects of Light Intensity on Growth, Anti-Stress Ability and Immune Function in Yellow Feathered Broilers by YL Guo (5160098)

“…There was a linear effect for T-AOC(p=0.002), GSH-Px(p≤0.047), MDA (p=0.003), H/L(p≤0.014), ANAE+ (p≤0.044), and antibody titer (p≤0.021) with T-AOC, GSH-Px, ANAE+, and antibody titer increased significantly as light intensity decreased, whereas MDA and H/L were decreased with the decrease in light intensity. …”

Clinical and virological profiles of chimeric strain pony infections. by Jodi K. Craigo (421284)

“…Febrile episodes are defined by achieving a combination of two-three features such as: rectal temperature above 39°C in conjunction with thrombocytopenia (platelet decrease of ≥70,000/µl of whole blood), EIAV viral load ≥10⁵ as well as other clinical signs of EIA. …”

Different cell fate in aortic valves between male and female RHD patients. by Feng Xiao (27219)

“…GAPDH expression is used to normalize the expression level. (H): Decreased expression of autophagy genes, BECN1 and LC3A, in aortic valves of female patients. n = 8 patients/group for TUNEL assay and Ki67 staining, n = 5 for RT-qPCR, *<i>p</i> < 0.05, **<i>p</i> < 0.01, scale bar = 100μm.…”

Bidirectional “switch” in TRIM29 regulation from normal epithelium to the respective carcinomas. by Ayelet Avraham (539937)

“…<p>TCGA data analysis: (<b>A</b>) TRIM29 promoter methylation (average of 5 Illumina probes, <b><a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0091805#pone.0091805.s005" target="_blank">Table S4B</a></b>) in normal and in cancer tissues. …”

Data_Sheet_2_Flavonoid Derivative of Cannabis Demonstrates Therapeutic Potential in Preclinical Models of Metastatic Pancreatic Cancer.pdf by Michele Moreau (5726120)

“…<p>Pancreatic cancer is particularly refractory to modern therapies, with a 5-year survival rate for patients at a dismal 8%. …”

Droplet Microfluidic System with On-Demand Trapping and Releasing of Droplet for Drug Screening Applications by Matthew Courtney (3396641)

“…This work demonstrates a droplet microfluidic platform that has the potential to significantly reduce the reagent consumption and shorten the reaction and analysis time by utilizing nanoliter-sized droplets as a replacement of wells. …”

Data_Sheet_1_Flavonoid Derivative of Cannabis Demonstrates Therapeutic Potential in Preclinical Models of Metastatic Pancreatic Cancer.pdf by Michele Moreau (5726120)

“…<p>Pancreatic cancer is particularly refractory to modern therapies, with a 5-year survival rate for patients at a dismal 8%. …”

Image_1_Flavonoid Derivative of Cannabis Demonstrates Therapeutic Potential in Preclinical Models of Metastatic Pancreatic Cancer.JPEG by Michele Moreau (5726120)

“…<p>Pancreatic cancer is particularly refractory to modern therapies, with a 5-year survival rate for patients at a dismal 8%. …”

Reduced (owner-animal metadata) XGBoost model on the <i>any health problem</i> binary using the all-owner dataset. by Richard Barrett-Jolley (739341)

“…<p>(a) Receiver operating characteristic curve of a reduced prediction model only containing owner and animal variables. …”

Fig 2 - by Hina Mushtaq (14885903)

“…Isolate HM49 recorded its protease enzyme activity from pH 6 (lowest) reaching its optimum at pH 8 followed by a gradual decrease up to pH 12 (2D). Temperature studies revealed its dynamism broadly in 5°C (lowest) to 40 °C range with its optimum activity being recorded at 20 °C (2E). …”

CoCl₂ induces abnormal neovascularization in zebrafish embryos. by Yu-Ching Wu (739844)

“…(B) With fluorescence excitation, ectopic SIV and excessive retinal vascularization are shown in CoCl_<b>2</b>-treated embryos compared with the untreated control. (C, D) A dose-dependent decrease in survival rates (four independent experiments; n = 35 in each group) in embryos treated with increasing concentrations (0–20 mM) and an increase in the vascular defect occurrence rate in the SIV and retinal vessels are shown (three independent experiments; n = 35 in each group). …”