Exposure to low CO₂ levels decreases ER cholesterol levels. by Nityanand Bolshette (17396845)

“…<b>(D, E)</b> The free cholesterol and cholesterol ester levels in the ER membrane from the cells as in <b>(C)</b>, were quantified with shotgun lipidomics analysis (see <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3002367#pbio.3002367.s007" target="_blank">S7 Fig</a> and <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3002367#pbio.3002367.s012" target="_blank">S5 Table</a>) (mean ± SE, <i>n</i> = 3 independent experiments, **<i>P</i> < 0.01, *<i>P</i> < 0.05, nonsignificant (ns) two-sided Student’s <i>t</i> test). …”

Simvastatin decreases cerebral vasospasm of the middle cerebral artery and reduces microthromboemboli after SAH. by Mohammed Sabri (355717)

“…<p><b>A.</b> Representative images showing vasospastic MCA in vehicle treated mice, as compared to larger diameter MCAs from the two simvastatin treated groups that are similar to MCA in naïve group. …”

Zebrafish harboring homozygous mutations in <i>gdf6</i> exhibit decreased endurance. by Michèle G. DuVal (278183)

“…</b> Open field tests of average swim velocity during 10 minutes of each hour through a circadian cycle, in tanks replicating lifetime husbandry conditions, show a lower mean movement at night (in either genotype, **p<0.01) but no difference between genotypes in any measure during day (p = 0.247) or night (p = 0.814).…”

Hsp90 inhibition decreases the adipogenic transcriptional program without any effect on cytotoxicity. by Sébastien Desarzens (547289)

Total tau levels are significantly decreased in the healthy older brains compared to the younger brains. by Shreyasi Chatterjee (3531506)

Etomoxir and orlistat inhibit cell cycle progression and decreased proliferation rate in myeloma cells. by José Manuel Tirado-Vélez (304970)

Increased osteoblastic activity and decreased osteoclastogenesis in TgLRAP cells <i>in vitro</i>. by Naoto Haruyama (487384)

“…Compared with the co-culture of WT BMCs and WT calvarial cells (WT / WT), the number of osteoclasts were significantly decreased at 50% in the co-cultures of TgLRAP BMCs and TgLRAP calvarial cells (TgLRAP / TgLRAP) (graph). …”

Aspirin decreases expression of NFκB and β-catenin in colon cancer cells. by Satya Pathi (301408)

“…<p>Decreased p65/p50 in RKO (A) and SW480 (B) cells. Cells were treated for 48 hr with 5 or 10 mM, and whole cell, nuclear and cytosolic extracts were analyzed by western blot analysis as described in the <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0048208#s3" target="_blank">Experimental Procedures</a>. …”

Decreased ISCs and increased goblet cells after intestinal specific loss of MLL1. by Neha Goveas (11790822)

“…(C) Decrease in ISC markers, OLFM4 and SOX9 in <i>Mll1</i>^{<i>FC/FC; Vil-Cre-ERT2/+</i>} intestinal sections. …”

DHT increases whereas orchidectomy decreases the weight and cross sectional area of hindlimb muscles. by Young-Eun Yoo (323357)

“…<b>A:</b> In WT mice, DHT increased the GN weight by 7% (212.4±8.8 mg), whereas orchidectomy decreased it by 14% (171.4±9.0 mg) compared with control WT mice (198.4±5.5 mg). …”

Ethanol decreases hepatic ATP and causes modest liver injury: protection by Alda-1. by Zhi Zhong (314411)

Simultaneous ablation of Syt1 and Syt7 decreases the RRP size at excitatory synapses. by Taulant Bacaj (803415)

“…<p><b>A & B.</b> Ablation of both Syt1 and Syt7 in hippocampal neurons decreases the RRP size at excitatory synapses in a manner that is rescued by WT Syt7 (Syt7^WT) or Syt1 (Syt1^WT) but not by mutant Syt7 (Syt7^C2A*^B*) or Syt1 (Syt1^C2A*^B*) with altered top-loop sequences containing the Ca²⁺-binding sequences (A, Syt7 rescue; B, Syt1 rescue). …”

Sildenafil treatment during recovery does not affect hyperoxia-induced decreases in alveolar counts. by Marta Perez (526067)

Decreased sensitivity of coculture HIV spread to RAL predicts multiple infections per cell. by Mikaël Boullé (3329427)

“…Blue dashed line represents parametrization of the cell-free infection response to RAL in terms of IC₅₀ (1.9 nM) and hill coefficient (0.7). Red dashed line represents the fit of coculture infection using the decreased sensitivity to RAL (<a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1005964#sec008" target="_blank">Materials and methods</a>). …”

GBE did not modify cell morphology but decreased reactive oxygen species (ROS) levels. by Virginie Rhein (243241)

“…<b>C</b>) Mitochondria-associated ROS levels measured after incubation with DHR (DHR fluorescence units/1×10⁵ cells). ROS levels showed a trend to be increased in APP cells compared to control cells (⁽*⁾p = 0.082, unpaired student's t-test, n = 11, values represent the means ± S.E.). …”

Rapamycin decreases Schwann cell markers, whereas statin induces Schwann cell markers. by Andrea Preitschopf (629851)

KCl treatment increases Elk1 SUMOylation and decreases katanin-p60 expression. by Ece Selçuk (436963)

Effects of bFGF on Cx46 and Cx50 in TtT/GF FS cells. by María Leiza Vitale (4287994)

“…Forty eight-49 kDa Cx46 was transiently and significantly increased by 30 min in the presence of bFGF († P<0.03). Cx50 increased after a 2 h incubation period with bFGF (# P<0.02 2 h vs 0 h), then slowly receded to control values by 24h in the presence of bFGF. …”

ROC curve and P-R curve (attack traffic proportion = 50%). by Longyan Ran (18452261)

The number of plasmacytoid dendritic cells (pDCs) decreased after anti-CXCR3 treatment and <i>T</i>. <i>cruzi</i> infection. by Camila Pontes Ferreira (6194006)