2‑Ethylhexyl Diphenyl Phosphate and Its Hydroxylated Metabolites are Anti-androgenic and Cause Adverse Reproductive Outcomes in Male Japanese Medaka (Oryzias latipes) حسب Yu Li (183836)

"…Although high concentrations of 2-ethylhexyl diphenyl phosphate (EHDPP) have been detected in wild fish, its reproductive toxicity in fish remains unclear. In this study, we for the first time observed that EHDPP elicited androgen receptor (AR) antagonistic activity with a 50% inhibitory concentration of 37.5 μM. 2-Ethyl-5-hydroxyhexyl diphenyl phosphate was proved to be the dominant metabolite of EHDPP in Japanese medaka and elicited 3.1-fold stronger AR antagonistic activity than that of EHDPP. …"

Top 10 pathways with the lowest p-value. حسب Rizka Fatriani (17485787)

"…Molecular docking results between PPARG and EP300 with the ten active compounds showed a binding affinity value of ≤ -5.0 kcal/mol in all dockings, indicating strong binding. …"

Does Mean Platelet Volume Decrease in the presence of Coronary Artery Fistula? حسب Isa Sincer (7234577)

"…Compared to the control group, median (IQR) High-density lipoprotein cholesterol (HDL) levels were significantly higher (p=0.04) and MPV levels were significantly lower in the CAF group (8.84 ± 1.71fL vs. 10.43 ± 1.34, p < 0.001). In the multivariate analysis, only MPV was a significant predictor of CAF (p < 0.001, 95% CI for OR: 0.438 (0.306-0.629). …"

Experimental outline. حسب Melissa A. MacIver (12850566)

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Table_1_Decreased Risk in the Pancreatic Cancer With History of Hay Fever: A Meta-Analysis.doc حسب Guannan Wang (2209297)

"…A history of hay fever was associated with a decreased risk of pancreatic cancer (OR, 0.57; 95% CI, 0.50–0.64, P < 0.00001) through fixed effect model.…"

Methods of assessment of the glottic gap using a rigid endoscope. حسب Ikuo Mikoshiba (9312007)

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Datasheet1_Impact of lockdown on children with type-1 diabetes: returning to the community was associated with a decrease in HbA1c.pdf حسب Benjamin Morat (17677977)

"…No significant difference was observed between medians of HbA1c_mean and HbA1c_after values (8.37% [7.88; 9.32%] vs. 8.50% [7.70; 9.50%], respectively; p = 0.391). Returning to the community was a protective factor [OR 0.31 (0.09–0.94); p = 0.045]. …"

Datasheet2_Impact of lockdown on children with type-1 diabetes: returning to the community was associated with a decrease in HbA1c.pdf حسب Benjamin Morat (17677977)

"…No significant difference was observed between medians of HbA1c_mean and HbA1c_after values (8.37% [7.88; 9.32%] vs. 8.50% [7.70; 9.50%], respectively; p = 0.391). Returning to the community was a protective factor [OR 0.31 (0.09–0.94); p = 0.045]. …"

Demographics and baseline characteristics of the safety population. حسب Rahsan Erdem (11726357)

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Grading of stool consistency and diarrhea severity. حسب Rahsan Erdem (11726357)

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Secondary efficacy endpoints for the modified intent-to-treat population. حسب Rahsan Erdem (11726357)

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Source data for Fig 1. حسب Rahsan Erdem (11726357)

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Source data for S1 and S2 Figs. حسب Rahsan Erdem (11726357)

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Source data for Fig 2. حسب Rahsan Erdem (11726357)

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Consolidated Standards for Reporting of Trials flow diagram. حسب Rahsan Erdem (11726357)

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Source data for Fig 3. حسب Rahsan Erdem (11726357)

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Diarrheal disease severity by treatment group for the modified intent-to-treat population. حسب Rahsan Erdem (11726357)

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iOWH032 inhibits cholera toxin-induced secretion in a mouse closed-loop model. حسب Rahsan Erdem (11726357)

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Study drug–related treatment-emergent adverse events by system organ class and preferred term in the safety population. حسب Rahsan Erdem (11726357)

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iOWH032 inhibits cholera toxin-induced fecal output in a cecectomized rat model. حسب Rahsan Erdem (11726357)

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