Chloro Half-Sandwich Osmium(II) Complexes:  Influence of Chelated N,N-Ligands on Hydrolysis, Guanine Binding, and Cytotoxicity by Anna F. A. Peacock (1297842)

“…Relatively little is known about the kinetics or the pharmacological potential of organometallic complexes of osmium compared to its lighter congeners, iron and ruthenium. We report the synthesis of seven new complexes, [(η⁶-arene)Os(NN)Cl]⁺, containing different bidentate nitrogen (N,N) chelators, and a dichlorido complex, [(η⁶-arene)Os(N)Cl₂]. …”

Chloro Half-Sandwich Osmium(II) Complexes:  Influence of Chelated N,N-Ligands on Hydrolysis, Guanine Binding, and Cytotoxicity by Anna F. A. Peacock (1297842)

“…Relatively little is known about the kinetics or the pharmacological potential of organometallic complexes of osmium compared to its lighter congeners, iron and ruthenium. We report the synthesis of seven new complexes, [(η⁶-arene)Os(NN)Cl]⁺, containing different bidentate nitrogen (N,N) chelators, and a dichlorido complex, [(η⁶-arene)Os(N)Cl₂]. …”

Chloro Half-Sandwich Osmium(II) Complexes:  Influence of Chelated N,N-Ligands on Hydrolysis, Guanine Binding, and Cytotoxicity by Anna F. A. Peacock (1297842)

“…Relatively little is known about the kinetics or the pharmacological potential of organometallic complexes of osmium compared to its lighter congeners, iron and ruthenium. We report the synthesis of seven new complexes, [(η⁶-arene)Os(NN)Cl]⁺, containing different bidentate nitrogen (N,N) chelators, and a dichlorido complex, [(η⁶-arene)Os(N)Cl₂]. …”

Chloro Half-Sandwich Osmium(II) Complexes:  Influence of Chelated N,N-Ligands on Hydrolysis, Guanine Binding, and Cytotoxicity by Anna F. A. Peacock (1297842)

“…Relatively little is known about the kinetics or the pharmacological potential of organometallic complexes of osmium compared to its lighter congeners, iron and ruthenium. We report the synthesis of seven new complexes, [(η⁶-arene)Os(NN)Cl]⁺, containing different bidentate nitrogen (N,N) chelators, and a dichlorido complex, [(η⁶-arene)Os(N)Cl₂]. …”

Rhodomyrtone decreases expression of inflammatory transcripts by TNF-α+IL-17A stimulated in skin organ cultures. by Julalak Chorachoo (5855852)

“…<p>Skin biopsies were pre-treated with 400 ng/ml rhodomyrtone 6 h before stimulation with 10 ng/ml TNF-α and 20 ng/ml IL-17A. Rhodomyrtone treatment decreases production of <i>DEFB4</i>, <i>IL1B</i>, <i>IL17C</i>, <i>IL36G</i>, <i>LCN2</i>, <i>PI3</i>, <i>S100A7</i>, and <i>S100A8</i> transcripts as measured by qRT-PCR at 72 h. …”

ILC3s decrease in adipose tissue but ILC2s remain the same. by Fred R. Sattler (9338330)

JNK inhibitor AS601245 decreased levels of Bim and CC3 proteins and reduced neuronal apoptosis and brain infarct volume in P7 rat after HI. by Deyuan Li (769599)

“…The infarct volume in the AS601245-treated brain was decreased by 58% compared with the DMSO controls (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0132998#pone.0132998.g004" target="_blank">Fig 4I</a>).…”

Fig 10 - by Qingzhou Zheng (12936804)

Decrease in adhesion during early development of <i>Dictyostelium discoideum</i>. by Marco Tarantola (102609)

Mutation in poliovirus 3A protein increases viral sensitivity to BFA and decreases recruitment of GBF1 to membranes. by George A. Belov (375765)

Serum IgA levels in CD89 transgenic mice were substantially decreased while IgA production by B lymphocytes was unaffected. by Lijun Xu (195394)

Confirmatory MDS of PVQ-21 items and HOVs from the K-S and SVS-10 instruments. by Oscar Smallenbroek (17509563)

13 thaxtomin A-resistant mutants were isolated from a screen of 10⁷ mutants. by Chloe Casey (14341756)

The J-domain of HSJ1a decreases the protein level of Atx3 through its chaperone binding. by Xue-Chao Gao (220511)

Increased oxidative stress, viral load and decreased survivability of N2a following RIG-I ablation. by Arshed Nazmi (215284)

Comparison of physiological and perceptual measures taken during Session 2 and Session 10 of a heat acclimation intervention in well-trained rowers. by Calvin P. Philp (12095878)

Inhibition of ADAM10 affects Notch targeted Hes5 and Gli genes in the ventral spinal cord (A–H) and in vitro cultured cell system (I–M). by Xin Yan (17064)

“…The ADAM10-mo transfected cells are green and the left side serves as a control. …”

Stabilized MetA decreases the frequencies of persisters in different <i>E. coli</i> strains at elevated temperature. by Elena A. Mordukhova (646403)

CXCL10 production is enhanced in the setting of HIV and HBV co-infection in vitro and decreased with the addition of antiretroviral agents efavirenz or raltegravir. by Kasha P. Singh (9354307)

Naturally occurring antibodies against serum amyloid A reduce IL-6 release from peripheral blood mononuclear cells by Tadeja Kuret (5059433)

“…Both anti-SAA and anti-SAA1α exhibited heterogeneous to high avidity and reached peak levels between 41–50 years, then diminished with age in the oldest group (51–67 years). …”