AKT and ERK1/2 pathways are required for arsenic-inducing HIF-1α expression and angiogenesis. by Ling-Zhi Liu (20849)

“…(C) BEAS-2B cells were infected with adenovirus carrying GFP (Ad-GFP) or AKT dominant negative (Ad-AKT-DN) at 20 MOI (upper panel), or transfected with scrambled control of siRNA (siScramble) or siMAPK at 50 nM (bottom panel). After 24 h, cells were treated with arsenic and angiogenesis assay was performed as above. *, indicates that the relative angiogenesis index was significantly decreased when compared with Ad-GFP or siScramble control group, <i>P</i><0.05.…”

Figure 1 raw data by Urban Bezeljak (8372241)

“…(I-K) Signal fold change, temporal delays and relative maximum rates from the stochastic simulations in H. We ran 50 individual stochastic simulations per condition.…”

Identification of host factors required for HCV RNA replication or IRES-mediated translation. by Qisheng Li (522711)

“…Values relative to siNT in the heatmap are depicted in a continuum of blue (reduced infection - more than 50% decrease of the replicon activity after siRNA-mediated silencing; proviral) to red (enhanced infection - more than 50% increase of the replicon activity after siRNA-mediated silencing; antiviral). …”

Multiple MPER lineages and specificities in CAP206 plasma. by Cathrine Scheepers (8129955)

“…<p><b>(A)</b> Longitudinal plasma sampled over three years (shown as weeks post-infection) were assayed against a multi-subtype panel of 23 viruses sensitive to CAP206 plasma shown as ID₅₀ [<a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1010450#ppat.1010450.ref023" target="_blank">23</a>]. …”

Rearrangement of actin cytoskeleton in treated and untreated MDA-MB 435 breast cancer cells by Robert F. Klees (62686)

“…</p><p></p> Cells were plated on fibronectin for 4 hours in the presence of either compound 9 (panel (c)), compound A5 (panel (d)), or compound A8 (panel (e)) at a final concentration of 15.2 ng/μl and were compared to the positive control (panel (a)) and the ethanol vehicle (panel (b)).Cells were fixed and stained for F-actin using TRITC-phalloidin. …”

Data_Sheet_1_Cerebrovascular Reactivity Assays Collateral Function in Carotid Stenosis.docx by Olivia Sobczyk (5412599)

“…Ipsilateral MCA territory CVR was less than normal in each class, including that with <50% stenosis (Student t-test, two-tailed; p = 0.0014 for GM and p = 0.030 for WM), with a trend of decreasing average CVR with increasing stenosis. …”

Wnt/β-catenin reduces <i>MKX</i> and <i>TNMD</i> expressions in <i>SCX</i>-programmed tendon progenitors (hMSC-Scx cells). by Yasuzumi Kishimoto (4282138)

“…Relative expressions of <i>AXIN2</i>, <i>MKX</i>, and <i>TNMD</i> in hMSC-Scx cells treated with 50 ng/ml Wnt3a with or without 5 μM IWR <b>(A)</b>, 0 to 2 μM BIO <b>(B)</b>, or 0 to 20 μM IWR <b>(C)</b> are indicated. …”

Kidney dysfunction and cerebral microbleeds in neurologically healthy adults by Sang Hyuck Kim (3752872)

“…The mean GFR level was 81.5 ± 15.5, and the prevalence of CMB was 4.1% (n = 103). Subjects with CMB demonstrated a higher proportion of moderate-to-severe renal dysfunction than those without CMB (15.5% vs. 5.0%, p < 0.001). …”

Histology of wild-type and <i>oltNH</i> hair follicles during hair follicle morphogenesis and the beginning of the first cycle. by Fabian Runkel (157823)

“…Bar  = 100 µm in images A to X, and 50 µm in images G* to L* and S* to X*.…”

53 proteins change in abundance with age. by Stephanie M. Zimmerman (449532)

CLAD_sequence_files by Ryan Hunter (21714311)

DataSheet_1_Identifying hub genes in response to ustekinumab and the impact of ustekinumab treatment on fibrosis in Crohn’s disease.zip by Ying Xu (9172)

“…Introduction<p>Crohn’s disease (CD) is a chronic inflammatory disease. Approximately 50% of patients with CD progressed from inflammation to fibrosis. …”

Table_1_Narrowing row spacing and adding inter-block promote the grain filling and flag leaf photosynthetic rate of wheat under enlarged drip tube spacing system.xlsx by Jianguo Jing (18767383)

“…The decline of NS22 (9.93%) was higher than that of NS44 (9.04%), and both cultivars also showed a greater decrease in grain weight and average grain-filling rate (AGFR) of inferior grains (NS22: 23.19%, 13.97%; NS44: 7.78%, 5.86%) than the superior grains (NS22: 10.60%, 8.33%; NS44: 4.89%, 4.62%). …”

DataSheet_1_Narrowing row spacing and adding inter-block promote the grain filling and flag leaf photosynthetic rate of wheat under enlarged drip tube spacing system.zip by Jianguo Jing (18767383)

“…The decline of NS22 (9.93%) was higher than that of NS44 (9.04%), and both cultivars also showed a greater decrease in grain weight and average grain-filling rate (AGFR) of inferior grains (NS22: 23.19%, 13.97%; NS44: 7.78%, 5.86%) than the superior grains (NS22: 10.60%, 8.33%; NS44: 4.89%, 4.62%). …”

Image1_Total flavonoids extracted from Penthorum chinense Pursh mitigates CCl4-induced hepatic fibrosis in rats via inactivation of TLR4-MyD88-mediated NF-κB pathways and regulatio... by Sujuan Wang (1865149)

“…Subsequently, rats were randomly assigned to a control group (Control), a carbon tetrachloride (CCl₄)-induced hepatic fibrosis model group (Model), a positive control group [0.2 mg/(kg∙day)] of Colchicine), and three TFPCP treatment groups [50, 100, and 150 mg/(kg∙day)]. …”

Image2_Total flavonoids extracted from Penthorum chinense Pursh mitigates CCl4-induced hepatic fibrosis in rats via inactivation of TLR4-MyD88-mediated NF-κB pathways and regulatio... by Sujuan Wang (1865149)

“…Subsequently, rats were randomly assigned to a control group (Control), a carbon tetrachloride (CCl₄)-induced hepatic fibrosis model group (Model), a positive control group [0.2 mg/(kg∙day)] of Colchicine), and three TFPCP treatment groups [50, 100, and 150 mg/(kg∙day)]. …”

<i>Lp</i> knockdown significantly impairs oogenesis and affects Vg expression and localization. by Iryna Stryapunina (17867390)

Data Sheet 1_HLA class, calcineurin inhibitor levels, and the risk of graft failure in kidney recipients with de novo donor-specific antibodies.pdf by Marc-Antoine Béland (20294229)

“…Additionally, the risk of graft loss decreased with increasing CNI trough levels following dnDSA detection (aHR 0.7 [0.6-0.9] for each increase in 1 ng/mL, p=0.02).…”

Data Sheet 2_HLA class, calcineurin inhibitor levels, and the risk of graft failure in kidney recipients with de novo donor-specific antibodies.pdf by Marc-Antoine Béland (20294229)

“…Additionally, the risk of graft loss decreased with increasing CNI trough levels following dnDSA detection (aHR 0.7 [0.6-0.9] for each increase in 1 ng/mL, p=0.02).…”

Synthetic tetracycline-inducible regulatory networks: computer-aided design of dynamic phenotypes-3 by Vassilios Sotiropoulos (96257)

“…(B) Average number of GFP molecules when 2000 molecules of Tc are added into the medium at time 2 × 10sec, using wild-type kinetics (WT/w 2000 Tc, blue line), a 10 fold (Des 2.1/w 2000 Tc, green line) and a 50 fold (Des 2.2/w 2000 Tc, red line) increase in the dissociation constant of both TetR and induced Tet-ON from of the gene encoding Tet-ON. …”