Showing 81 - 100 results of 6,913 for search '(( 50 ((ngn decrease) OR (nn decrease)) ) OR ((( 50 n decrease ) OR ( 10 nm decrease ))))', query time: 0.74s Refine Results
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    Discovery of Novel Pyrimidine-Based Capsid Assembly Modulators as Potent Anti-HBV Agents by WooChan Kim (10690503)

    Published 2021
    “…One of the synthesized derivatives, compound <b>23h</b> (R<sup>1</sup> = MeSO<sub>2</sub>, R<sup>2</sup> = 1-piperidin-4-amine, R<sup>3</sup> = 3-Cl-4-F-aniline) displayed potent inhibitory effects in the in vitro assays (52% inhibition in the protein-based assay at 100 nM and an IC<sub>50</sub> value of 181 nM in the serum HBV DNA quantification assay). …”
  8. 88

    Discovery of Triazolyl Derivatives of Cucurbitacin B Targeting IGF2BP1 against Non-Small Cell Lung Cancer by Fan-Fan Shang (16953264)

    Published 2023
    “…Derivative <b>A11</b> directly binds to the insulin-like growth factor 2 mRNA-binding protein 1 (IGF2BP1) protein with a <i>K</i><sub>D</sub> value of 2.88 nM, which is about 23-fold more potent than CuB, leading to the decreased expression of downstream apoptosis- and cell cycle-related proteins. …”
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    Temporal profiles of the key BO-NN features. by Julia Berezutskaya (9080269)

    Published 2020
    “…Right plot show the gradual decrease in the TM tuning for the features highlighted in <b>c</b> as well as the gradual increase in the temporal response profile (i.e. optimal shifts for the prediction of the key BO-NN features using Praat features shown in <b>a</b>). …”
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