Discovery of Dual-Acting Biofilm Inhibitors against Pseudomonas aeruginosa by the Coupling of 3‑Hydroxypyridin-4(1<i>H</i>)‑ones with <i>N</i>‑Phenylamide QS Inhibitors by Hao-Zhong Long (19685972)

Subjects:

HbA1c, BMI and Lipid levels of study participants (n = 382). by Habiba I. Ali (10451382)

ABT199 inhibits ALK ^mutant kinase activity and decreases it phosphorylation. by Richard Junior Zapata Dongo (17912565)

Mean observer DCCR (%) and DDR (%) at C3-4 in neutral and flexed neck positions in horses that were not operated (n = 18) versus were operated (n = 4) at this site. by Devon England (21262225)

Mean observer DCCR (%) and DDR (%) at C6-7 in neutral, flexed and extended neck positions in horses that were not operated (n = 13) versus operated (n = 9) at this site. by Devon England (21262225)

Mean observer DCCR (%) and DDR (%) at C5-6 in neutral, flexed and extended neck positions in horses that were not operated (n = 16) versus operated (n = 6) at this site. by Devon England (21262225)

Mean observer DCCR (%) and DDR (%) at C4-5 in neutral, flexed and extended neck positions in horses that were not operated (n = 10) versus operated (n = 12) at this site. by Devon England (21262225)

Anaesthesia decreases stimulus-specific suppression on probe-responses only after communication context. by Luciana López-Jury (8601540)

Decreasing neural activity in MBONs that suppress PER when activated has modest effects. by Justine Chia (5459294)

EGFR/ERK signaling activity decreases throughout LEC elimination with endocytic activity dependency. by Kevin Yuswan (19845885)

Alternative bounded and monotonically decreasing functions do not accurately fit the bias in the naïve SI. by Liron Sheintuch (12078310)

ΔAMP null mutants exhibit decreased climbing and increased sleep after TBI. by Bart van Alphen (12003724)

“…<p>(<b>A)</b> ΔAMP null mutants show decreased climbing 24 hours after TBI, similar to controls (<i>n</i> = 50–66) <b>(B)</b> Sleep is decreased in controls 24 hour after TBI <b>(C)</b> but is increased in ΔAMP null mutants (<i>n</i> = 56–95). *** <i>p</i> < 0.001, * <i>p</i> < 0.05 by <i>t</i> tests with Bonferroni correction. …”

Decrease of the DXR-induced genotoxicity and nongenotoxic effects of Theobroma cacao revealed by micronucleus assay by M. F. G. Boriollo (4894975)

Running increased neural stem cell proliferation in the dentate gyrus, but did not decrease inflammation. by Kaja Falkenhain (9317016)

Juvenile demyelination leads to a substantial decrease in potassium currents in PV interneurons of the PFC. by Sara Hijazi (21656615)

“…Representative images of double immunostaining of PV interneurons (red) and Kv3.1b (cyan) in the PFC in control and cuprizone mice; scale bar: 50 µm. <b>F, G</b>. PV intensity was not altered following juvenile demyelination (<i>t test of</i> <b><i>(F)</i></b><i>; n = 4 mice per group, p = 0.3888; t test of</i> <b><i>(G)</i></b><i>; n = 145/170 cells from 4 mice per group, p = 0.3067</i>). …”

Decreased ISCs and increased goblet cells after intestinal specific loss of MLL1. by Neha Goveas (11790822)

“…Mean ± s.d. is shown (p = 0.007, Student’s <i>t</i>-test). (C) Decrease in ISC markers, OLFM4 and SOX9 in <i>Mll1</i>^{<i>FC/FC; Vil-Cre-ERT2/+</i>} intestinal sections. …”

Exposure to low CO₂ levels decreases ER cholesterol levels. by Nityanand Bolshette (17396845)

“…<b>(F)</b> qPCR analysis for cholesterogenic genes from NIH3T3 cells exposed to cholesterol (50 μm) or 25-hydroxycholesterol (10 μm) under 5% or 1% CO₂ for 4 h (mean ± SE, <i>n</i> = 3 biological replicates per condition, ***<i>P</i> < 0.001, nonsignificant (ns), two-way ANOVA with Bonferroni’s multiple comparisons test). …”

Loss of <i>Nf1</i> increases sleep fragmentation and decreases sleep depth. by Elizabeth B. Brown (4582978)

“…Compared to controls, pan-neuronal knockdown of <i>Nf1</i> significantly reduces bout length during the day (nsyb/+, <i>P</i><0.0178; <i>Nf1</i>^RNAi/+, <i>P</i><0.0253) and night (nsyb/+, <i>P</i><0.0001; <i>Nf1</i>^RNAi/+, <i>P</i><0.0001). N = 50–55. <b>(G-N)</b>. The <i>Drosophila</i> Arousal Tracking (DART) was used to probe arousal threshold and reactivity measurements. …”

Binary and ordinal logistic regression analysis of predictors for the occurrence of ISR > 50%. by Jae-Chan Ryu (2850581)

Evaluation of disease activity for rheumatic diseases in the VTE group (n = 50). by Qing Peng (148438)