Docetaxel and quercetin-loaded lipid nanocarrier optimized by quality by design for glioblastoma therapy: a ligand-conjugated and therapeutic repurposing approach by Zufika Qamar (22259678)

“…Compared to non-conjugated NLC and (DTX-QUR) suspension (SUS), Tf-(DTX-QUR) NLC showed 3.6- and 5.8-fold decrease in IC₅₀, respectively. Cellular uptake studies demonstrated significantly (<i>***p < 0.001</i>) high internalization of Tf-conjugated NLC to U87-MG cells. …”

Table 1_A structural genomics approach to investigate Dystrophin mutations and their impact on the molecular pathways of Duchenne muscular dystrophy.docx by Abdelbaset Mohamed Elasbali (11638732)

“…Seventeen mutations were localized in the Calponin-homology (CH) 1 domain, a critical functional region of Dystrophin. Six substitutions (N26H, N26K, G47W, D98G, G109A, and G109R) were predicted to decrease protein solubility and were located in minimally frustrated regions, potentially compromising Dystrophin functionality and contributing to DMD pathogenesis.…”

Data_Sheet_1_Nanoformulation of Talazoparib Delays Tumor Progression and Ascites Formation in a Late Stage Cancer Model.pdf by Paige Baldwin (6688517)

“…Dose response analysis indicated that the murine cell lines with conditional BRCA1/2, PTEN, and TP53 deletions had the lowest IC50s. NanoTalazoparib administered on a schedule of three doses weekly slowed disease progression and resulted in significantly less mice with ascites at the end point compared to controls. …”

File S1 - Modifications in Rat Plasma Proteome after Remote Ischemic Preconditioning (RIPC) Stimulus: Identification by a SELDI-TOF-MS Approach by Pierre Hibert (470627)

“…Detailed <i>p-</i>value data for comparison between the three groups is indicated in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0085669#pone-0085669-t002" target="_blank">Table 2</a>. …”

Image1_Bioglass/ceria nanoparticle hybrids for the treatment of seroma: a comparative long-term study in rats.tif by Michael-Alexander Pais (18139264)

“…</p><p>Results: NP-treated sides showed no macroscopically visible seroma formation after application on POD 7, in stark contrast to the fibrin-treated sides, where 60% of the rats had seromas on POD 14, and 50% on POD 21. At the endpoint (POD 42), sides treated with nanoparticles (NPs) exhibited significant macroscopic differences compared to other groups, including the absence of a cavity, and increased fibrous adhesions. …”

Table_1_Total and cause-specific mortality associated with meat intake in a large cohort study in Korea.docx by Anthony Kityo (14782057)

“…Background<p>Asia has experienced a large increase in meat intake in the past decade, yet the health impact of meat intake is not well studied.…”

Table_3_A CRISPR/Cas9-mediated screen identifies determinants of early plasma cell differentiation.xlsx by Ermeng Xiong (11176635)

“…Defective plasmablast formation caused by Ern1 deletion could not be rescued by the active, spliced form of XBP1 whose processing is dependent on and downstream of IRE1a, suggesting that in early plasma cell differentiation IRE1a acts independently of XBP1. …”

Evaluation of a Dengue NS1 Antigen Detection Assay Sensitivity and Specificity for the Diagnosis of Acute Dengue Virus Infection by Laura L. Hermann (638244)

“…We found significant variation in the sensitivity of the InBios NS1 ELISA kit depending on the serotype of the dengue virus and also found decreasing sensitivity the longer after the onset of illness, showing 100% sensitivity early during illness, but dropping below 50% by Day 7.…”

Table1_Bioglass/ceria nanoparticle hybrids for the treatment of seroma: a comparative long-term study in rats.DOCX by Michael-Alexander Pais (18139264)

“…</p><p>Results: NP-treated sides showed no macroscopically visible seroma formation after application on POD 7, in stark contrast to the fibrin-treated sides, where 60% of the rats had seromas on POD 14, and 50% on POD 21. At the endpoint (POD 42), sides treated with nanoparticles (NPs) exhibited significant macroscopic differences compared to other groups, including the absence of a cavity, and increased fibrous adhesions. …”

Table_2_A CRISPR/Cas9-mediated screen identifies determinants of early plasma cell differentiation.xlsx by Ermeng Xiong (11176635)

“…Defective plasmablast formation caused by Ern1 deletion could not be rescued by the active, spliced form of XBP1 whose processing is dependent on and downstream of IRE1a, suggesting that in early plasma cell differentiation IRE1a acts independently of XBP1. …”

Image2_Bioglass/ceria nanoparticle hybrids for the treatment of seroma: a comparative long-term study in rats.tif by Michael-Alexander Pais (18139264)

“…</p><p>Results: NP-treated sides showed no macroscopically visible seroma formation after application on POD 7, in stark contrast to the fibrin-treated sides, where 60% of the rats had seromas on POD 14, and 50% on POD 21. At the endpoint (POD 42), sides treated with nanoparticles (NPs) exhibited significant macroscopic differences compared to other groups, including the absence of a cavity, and increased fibrous adhesions. …”

The Effect of Elevated Ozone Concentrations with Varying Shading on Dry Matter Loss in a Winter Wheat-Producing Region in China by Jingxin Xu (790646)

“…In this study, we investigated the effect of a combination of elevated ozone concentrations and reduced solar irradiance on a popular winter wheat Yangmai13 (<i>Triticum aestivum</i> L.) at field and regional levels in China. …”

Image3_Bioglass/ceria nanoparticle hybrids for the treatment of seroma: a comparative long-term study in rats.tif by Michael-Alexander Pais (18139264)

“…</p><p>Results: NP-treated sides showed no macroscopically visible seroma formation after application on POD 7, in stark contrast to the fibrin-treated sides, where 60% of the rats had seromas on POD 14, and 50% on POD 21. At the endpoint (POD 42), sides treated with nanoparticles (NPs) exhibited significant macroscopic differences compared to other groups, including the absence of a cavity, and increased fibrous adhesions. …”

Data_Sheet_1_Altered zinc homeostasis in a primary cell culture model of the retinal pigment epithelium.DOCX by Ana Álvarez-Barrios (15301603)

“…In this study, we used a primary human fetal RPE cell culture model producing sub-RPE deposits accumulation that recapitulates features of early AMD to study Zn homeostasis and metalloproteins changes. …”

Image4_Bioglass/ceria nanoparticle hybrids for the treatment of seroma: a comparative long-term study in rats.tif by Michael-Alexander Pais (18139264)

“…</p><p>Results: NP-treated sides showed no macroscopically visible seroma formation after application on POD 7, in stark contrast to the fibrin-treated sides, where 60% of the rats had seromas on POD 14, and 50% on POD 21. At the endpoint (POD 42), sides treated with nanoparticles (NPs) exhibited significant macroscopic differences compared to other groups, including the absence of a cavity, and increased fibrous adhesions. …”

From Molecular Wires to Molecular Resistors: TCNE, a Class-III/Class-II Mixed-Valence Chemical Switch by Alexandre Burgun (1760278)

“…NIR spectroscopy of the salt <b>[2FeRu]­[C</b>_<b>3</b><b>(CN)</b>_<b>5</b><b>]</b> demonstrated that the coupling between the iron and ruthenium centers is not completely removed by addition of TCNE to <b>[1FeRu]⁺</b>, but has produced a very strong attenuation of the electronic coupling from <i>H</i>_ab = 0.50 eV to <i>H</i>_ab = 0.03 eV.…”

Table_1_Total and cause-specific mortality associated with meat intake in a large cohort study in Korea.docx by Anthony Kityo (14782057)

“…Background<p>Asia has experienced a large increase in meat intake in the past decade, yet the health impact of meat intake is not well studied.…”

Table1_Neonatal outcomes in preterm infants with severe congenital heart disease: a national cohort analysis.pdf by Safwat Aly (18346473)

“…This included 27%, 58%, and 15% in groups A, B, and C respectively. The incidence of severe CHD was highest between 25 and 28 weeks of gestation and decreased significantly with increasing GA up to 36 weeks (p < 0.001). …”

Table_4_A CRISPR/Cas9-mediated screen identifies determinants of early plasma cell differentiation.xlsx by Ermeng Xiong (11176635)

“…Defective plasmablast formation caused by Ern1 deletion could not be rescued by the active, spliced form of XBP1 whose processing is dependent on and downstream of IRE1a, suggesting that in early plasma cell differentiation IRE1a acts independently of XBP1. …”

Table_1_Vaccination completeness in children with rheumatic diseases: A longitudinal, observational multicenter cohort study in Switzerland.DOCX by Tatjana Welzel (11753417)

“…Annual non-live influenza vaccination was complete in 24.2% of children during IST; adherence decreased over the disease course.</p>Discussion<p>This study identified a low overall vaccination completeness in children with PRD. …”