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point decrease » point increase (Expand Search)
nn decrease » _ decrease (Expand Search), gy decreased (Expand Search), b1 decreased (Expand Search)
a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
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12061
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12066
Discovery of 2‑Ethoxy-5-isobutyramido‑<i>N</i>‑1-substituted Benzamide Derivatives as Selective Kv2.1 Inhibitors with In Vivo Neuroprotective Effects
Published 2023“…In this work, a series of novel benzamide derivatives were designed and synthesized as Kv2.1 inhibitors, and extensive structure–activity relationships led to highly potent and selective Kv2.1 inhibitors having IC<sub>50</sub> values of 10<sup>–8</sup> M. …”
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12067
Discovery of 2‑Ethoxy-5-isobutyramido‑<i>N</i>‑1-substituted Benzamide Derivatives as Selective Kv2.1 Inhibitors with In Vivo Neuroprotective Effects
Published 2023“…In this work, a series of novel benzamide derivatives were designed and synthesized as Kv2.1 inhibitors, and extensive structure–activity relationships led to highly potent and selective Kv2.1 inhibitors having IC<sub>50</sub> values of 10<sup>–8</sup> M. …”
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12068
Discovery of 2‑Ethoxy-5-isobutyramido‑<i>N</i>‑1-substituted Benzamide Derivatives as Selective Kv2.1 Inhibitors with In Vivo Neuroprotective Effects
Published 2023“…In this work, a series of novel benzamide derivatives were designed and synthesized as Kv2.1 inhibitors, and extensive structure–activity relationships led to highly potent and selective Kv2.1 inhibitors having IC<sub>50</sub> values of 10<sup>–8</sup> M. …”
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12069
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12070
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12071
DataSheet1_The Variants at APOA1 and APOA4 Contribute to the Susceptibility of Schizophrenia With Inhibiting mRNA Expression in Peripheral Blood Leukocytes.pdf
Published 2021“…After the SZ patients received an average of 27.50 ± 9.90 days of antipsychotic treatment, the median (interquartile) of serum apoA1 in the SZ episode significantly increased from 1.03 (1.00.1.20) g/L to 1.08 (1.00.1.22) g/L with the p-value of 0.044.…”
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12072
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12073
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12074
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12075
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12076
Novel Antagonist of the Type 2 Lysophosphatidic Acid Receptor (LPA<sub>2</sub>), UCM-14216, Ameliorates Spinal Cord Injury in Mice
Published 2022“…Inhibition of the type 2 lysophosphatidic acid receptor (LPA<sub>2</sub>) has recently emerged as a new potential pharmacological approach to decrease SCI-associated damage. …”
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12077
Novel Antagonist of the Type 2 Lysophosphatidic Acid Receptor (LPA<sub>2</sub>), UCM-14216, Ameliorates Spinal Cord Injury in Mice
Published 2022“…Inhibition of the type 2 lysophosphatidic acid receptor (LPA<sub>2</sub>) has recently emerged as a new potential pharmacological approach to decrease SCI-associated damage. …”
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12078
Dynamic reduction of thrombin generation parameters over time in a severe haemophilia A population.
Published 2013“…<p>Thrombin generating capacity was simulated by inputting each subject's factor composition into our mathematical model. Each point (circle) in the figure is representative of a single individual's thrombin generating capacity. …”
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12079
Synthesis and Biological Evaluation of Peripheral 5HT<sub>2B</sub> Antagonists for Liver Fibrosis
Published 2025“…<b>19c</b> markedly reduced fibrotic deposition, with a decrease in fibrosis stage and area in the CCl<sub>4</sub>-induced liver fibrosis mouse model. …”
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12080
Synthesis and Biological Evaluation of Peripheral 5HT<sub>2B</sub> Antagonists for Liver Fibrosis
Published 2025“…<b>19c</b> markedly reduced fibrotic deposition, with a decrease in fibrosis stage and area in the CCl<sub>4</sub>-induced liver fibrosis mouse model. …”