Discovery of the Triazolo[1,5‑<i>a</i>]Pyrimidine-Based Derivative WS-898 as a Highly Efficacious and Orally Bioavailable ABCB1 Inhibitor Capable of Overcoming Multidrug Resistance... by Shuai Wang (109515)

Subjects:

Discovery of the Triazolo[1,5‑<i>a</i>]Pyrimidine-Based Derivative WS-898 as a Highly Efficacious and Orally Bioavailable ABCB1 Inhibitor Capable of Overcoming Multidrug Resistance... by Shuai Wang (109515)

Subjects:

Compound CID 9998128 Is a Potential Multitarget Drug for Alzheimer’s Disease by Nguyen Quoc Thai (5348798)

“…Moreover, the compound dose-dependently decreases β-site amyloid precursor protein cleaving enzyme (BACE-1) activity with EC₅₀ value in micromolar range. …”

Compound CID 9998128 Is a Potential Multitarget Drug for Alzheimer’s Disease by Nguyen Quoc Thai (5348798)

“…Moreover, the compound dose-dependently decreases β-site amyloid precursor protein cleaving enzyme (BACE-1) activity with EC₅₀ value in micromolar range. …”

Supplementary Material for: Use of the Myocardial Performance Index in Decreased Fetal Movement Assessment: A Case-Control Study by Ho D. (4108837)

“…<p><b><i>Objectives:</i></b> To determine whether there are any fetal cardiac function changes, as measured by the myocardial performance index (MPI), in pregnancies complicated by decreased fetal movement (DFM). <b><i>Methods:</i></b> We performed a prospective cross-sectional case-control study of 50 DFM and 50 uncomplicated third-trimester pregnancies matched within 2 gestational weeks. …”

Group mean values and standard deviation of the normalized maximal torques (NMT) in the knee extensors (KE), the hip abductors (AB), and the hip adductors (AD) as well as for the r... by Franziska Daun (6433328)

Prevalence of antimicrobial resistance to folate pathway inhibitors exhibits a decreasing linear trend from 2002–2016. by Kelly E. Davidson (5464472)

Methotrexate susceptibility of <i>L</i>. <i>major</i> Friedlin mutants derived from a Mut-seq screen. by Sophia Bigot (16469992)

M344 decreases orthotopic pancreatic tumor growth when used as a treatment alone or in combination with gemcitabine. by Shelby M. Knoche (13833807)

Drive dynamics for split^<50cM <i>ClvR</i>s with different genetic linkage and migration rates. by Georg Oberhofer (3401438)

Temporal changes in the RPR titer from before to after treatment. by Kazuhiko Ikeuchi (9234268)

A Wearable Dual-Modal Patch for Rapid Pre-Hospital Diagnosis of Acute Myocardial Infarction by Kuo Yang (280921)

“…The time required for diagnosing ischemia was significantly reduced to 50 min after its onset. The patch is optimally integrated into a stamp-sized band-aid, accompanied by a smartphone app for data visualization and real-time analysis. …”

A Wearable Dual-Modal Patch for Rapid Pre-Hospital Diagnosis of Acute Myocardial Infarction by Kuo Yang (280921)

“…The time required for diagnosing ischemia was significantly reduced to 50 min after its onset. The patch is optimally integrated into a stamp-sized band-aid, accompanied by a smartphone app for data visualization and real-time analysis. …”

A Wearable Dual-Modal Patch for Rapid Pre-Hospital Diagnosis of Acute Myocardial Infarction by Kuo Yang (280921)

“…The time required for diagnosing ischemia was significantly reduced to 50 min after its onset. The patch is optimally integrated into a stamp-sized band-aid, accompanied by a smartphone app for data visualization and real-time analysis. …”

Significant clusters: Coronal PET images showing brain regions with significant (p < 0.001 and K > 50) metabolic inhibition (A-G) and activation (H-I) in rats following cocaine sel... by Christopher Rowan (21499924)

Association of polymorphic IC_50s versus wild<i>-</i>type at codon 876 in selected drugs tested. by Winnie Okore (14139712)

NEXLPL+/- mice have multiple neurobehavioral abnormalities. by Tian Yu (117385)

Shoot and root fresh and dry weights, shoot and root lengths of two cultivars of cauliflower (<i>Brassica oleracea</i> L.) plants foliarly treated with thiamin (50 and 100 mM) subj... by Munifa Jabeen (12634746)

PACAP increases NSC viability in response to hypoglycaemic <i>milieu</i> in correlation with a downward trend in apoptosis. by Shiva Mansouri (2838086)

The in vitro antitumor IC₅₀ values of protodioscin or dioscin against adenocarcinoma tumor cells (MDA-MB-468, MCF-7) and normal cells (PBMCs). by Najat Bouchmaa (13558816)