The RBPJ AOS variants show dysregulated Notch target gene expression when compared to WT RBPJ. by Ellen K. Gagliani (11478756)

“…Cells were additionally transfected with increasing concentrations (50, 150 & 250 ng) of either WT, NBM (F261A/V263A/R422E/E425R/E398R), KRS (K195E/R218H/S221D), NBM/KRS, or K195E Rbpj constructs in panels <b><i>ii-iv</i></b>. …”

Placental TLR/NLR expression signatures are altered with gestational age and inflammation by Navin Kumar (456620)

“…Increase in NFKBIA seen in PPROM and CA might represent a counter regulatory mechanism to decrease inflammation in these conditions. …”

Image_1_Assessment of Epigenetic and Phenotypic Variation in Populus nigra Regenerated via Sequential Regeneration.tif by Weixi Zhang (1626823)

“…About 10.86–26.80% of CCGG sites in the regenerated plant genome were demethylated and 5.50–8.45% were methylated, resulting in significantly lower DNA methylation levels among all regenerated plants than among donor plants. …”

Data_Sheet_1_Reducing culture medium nitrogen supply coupled with replenishing carbon nutrient simultaneously enhances the biomass and lipid production of Chlamydomonas reinhardtii... by Shiyan Zheng (13860734)

“…Results showed that replenishing 6 g/L sodium acetate (NaAc) could increase 1.50 and 1.53 times biomass and lipid productivity compared with 0 g/L NaAc treatment (the control), but total lipid content slightly decreased. …”

Table 1_High intensity human activity limits ultra-high altitude soil microbial community dispersal and keystone taxa distribution in southeastern Tibetan Plateau.xlsx by Wenzu Liu (22364023)

“…Human activities increase the complexity of microbial networks but decrease the stability of soil micro-ecosystems. As elevtation increases, the dispersal limitation of microbial communities decreases (total effect size: bacterial = −0.705, fungal = −0.745). …”

Transmural Ultrasound Imaging of Thermal Lesion and Action Potential Changes in Perfused Canine Cardiac Wedge Preparations by High Intensity Focused Ultrasound Ablation by Ziqi Wu (496313)

“…Spatiotemporally correlated AP measurements and ultrasound imaging allowed quantification of the reduction of AP amplitude (APA), shortening of AP duration at 50% repolarization, AP triangulation, decrease of optical AP rise, and change of conduction velocity along tissue depth direction within and surrounding HIFU lesions. …”

Analysis of SMN levels in different tissues of severe SMA mice. by Francesca Gabanella (34598)

“…(C) Analysis of SMN decrease in the spinal cord of severe SMA mice. Western blot analysis of the indicated serial dilutions (100 equals 50 µg of proteins) of whole tissue extracts from the spinal cord of normal (<i>SMN2</i>^+/+;<i>mSmn</i>^+/+), carrier (<i>SMN2</i>^+/+;<i>mSmn</i>^+/−) and severe SMA (<i>SMN2</i>^+/+;<i>mSmn</i>^−/−) mice at postnatal day 3. …”

Convallatoxin suppresses osteosarcoma cell proliferation, migration, invasion, and enhances osteogenic differentiation by downregulating parathyroid hormone receptor 1 (PTHR1) expr... by Xin Liu (43569)

“…<p>Osteosarcoma (OS) is the most common primary malignant bone tumor in children and adolescents. Convallatoxin, a natural cardiac glycoside, exhibits potent anti-tumor activities. …”

Table_1_Lactose-Induced Chronic Diarrhea Results From Abnormal Luminal Microbial Fermentation and Disorder of Ion Transport in the Colon.XLS by Hong Xue (28736)

“…The concentrations of lactose, galactose and lactic acid of the cecal content were markedly increased (P < 0.01) and SCFA concentration was significantly decreased (P < 0.01). This was associated with depletion of the Lachnospiraceae NK4A136 group and Ruminococcaceae UCG-005 and increased relative abundance of Lactobacillus, escherichia-shigella and megamonas in the cecal microbiota. …”

Changes in Patch Features May Exacerbate or Compensate for the Effect of Habitat Loss on Forest Bird Populations by Ainhoa Magrach (124536)

“…Satellite image analyses revealed that, from 1985 to 2008, forested area decreased by 8.8% and the remaining forest fragments became 16% smaller, 58–73% more isolated and 11–50% more regular. …”

Data Sheet 1_High intensity human activity limits ultra-high altitude soil microbial community dispersal and keystone taxa distribution in southeastern Tibetan Plateau.docx by Wenzu Liu (22364023)

“…Human activities increase the complexity of microbial networks but decrease the stability of soil micro-ecosystems. As elevtation increases, the dispersal limitation of microbial communities decreases (total effect size: bacterial = −0.705, fungal = −0.745). …”

Histological analysis for neurons and myelin. by Svitlana Garbuzova-Davis (81764)

“…Contralateral striatosomes also showed size decreases similar to striatosomes within infarct area. …”

An <i>in-silico</i> analysis to identify structural, functional and regulatory role of SNPs in <i>hMRE11</i> by Bhoomi Tarapara (11977197)

“…<p>Meiotic recombination 11 (<i>MRE11</i>) is a component of the tri-molecular <i>MRE11</i>-RAD50-NBS1 (MRN) complex, which functions as an exonuclease and endonuclease which is involved in identifying, signalling, protecting and repairing double-strand breaks in DNA (DSBs). …”

DataSheet_1_Effects of the neurotoxin β-N-methylamino-L-alanine (BMAA) on the early embryonic development of marine shellfish and fish.docx by Yilei Fu (14287574)

“…A sustained and dose-dependent decrease in heart rate was apparent in marine medaka embryos at 9-days post fertilization following BMAA exposure. …”

Extraction and characterization of biofunctional lignocellulosic fibers from Pulicaria undulata plant and the effect of alkali treatment on their bio-physicochemical properties by Mohammed, Alsafran

“…In contrast, alkali-treated fibers showed a significant decrease in radical scavenging activity (almost 7–8 fold) and reducing power potential (6-fold) and exhibited no antifungal activity, potentially due to the loss of bioactive components such as lignin and essential oils. …”
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Wnk signals through Fray to regulate glial potassium flux. by Lorenzo Lones (14374536)

Plot of the modeled association between weight change and activity tracking frequency for both genders, over all activities, and for different monitoring durations. by Arya Pourzanjani (800874)

“…In general, increased monitoring duration is associated with decreased weight loss per month and a weaker association between tracking frequency and weight change. …”

Effect of recombinant APN on fertilization and embryonic development. by Amena Khatun (4405552)

“…<p>(A) Blastocyst quality in the control and APN-treated groups (Bar = 50 μM). …”

Photoperiodic analyses of egg diapause induction and initiation in <i>Aedes albopictus</i>. by Guillaume Lacour (446652)

“…The sigmoid response curves ignore the field data points of decreasing diapause incidence for day length ≤ 11.5 hours, as these outliers are probably the result of a selection trend. …”

Effects of COS on the expression of MCP-1 and iNOS mRNA in RGC-5 cells. by I-Mo Fang (470460)

“…<p>RGC-5 cells were stimulated with 0.5mM PQ and then treated with 50 μg/ml (low-dose) or 100 μg/ml (high-dose) COS for 12 hours. …”