Potent Sensitisation of Cancer Cells to Anticancer Drugs by a Quadruple Mutant of the Human Deoxycytidine Kinase by Safiatou T. Coulibaly (816058)

“…Here, starting from the G12 variant itself, we generated a new library and identified a mutant (M36) that triggers even greater sensitisation to gemcitabine than G12. …”

Glycolytic inhibition by decreasing availability of NAD⁺ contributes to defective hyphae and biofilm formation of <i>nuo2</i>Δ/Δ cells under mannitol condition. by Xinhua Huang (1905940)

GCase activity is significantly decreased in the brain and liver of the homozygous <i>GBA1</i> D409V KI mouse model at 4, 8, and 12 months of age. by Nicole K. Polinski (10947787)

“…In whole brain homogenate (A,C) and liver homogenate (B,D), GCase activity is significantly decreased in the <i>GBA1</i> D409V KI homozygous (HOM) mice as compared to C57Bl/6 wild type (WT) mice (n = 7/group). …”

Antineoplastic Effects of siRNA against TMPRSS2-ERG Junction Oncogene in Prostate Cancer by Giorgia Urbinati (554921)

“…The siRNA against TMPRSS2-ERG fusion variant IV showed the highest anti-proliferative effects: Significantly decreased cell viability, increased cleaved caspase-3 and inhibited a cluster of anti-apoptotic proteins. …”

Barbie’s ankle equinus measured at 50 degrees as equnius posture (a) and flat foot posture measured at 0 degrees (b), with a handheld goniometer. by Cylie Williams (3446018)

Upregulation of autophagy decreases the age-related accumulation of hyperphosphorylated tau and ameliorates tau-induced locomotor defects in human Tau (0N3R) expressing transgenic... by Shreyasi Chatterjee (3531506)

List of mRNAs that are differentially expressed in both the RNAPII ChIP-seq and RNA-seq datasets, mRNAs with decreased expression in both lists, and mRNAs that have decreased expre... by Katherine I. Farley-Barnes (9258036)

“…<p>List of mRNAs that are differentially expressed in both the RNAPII ChIP-seq and RNA-seq datasets, mRNAs with decreased expression in both lists, and mRNAs that have decreased expression in both lists and are also nucleolar in at least 1 database [<a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1008967#pgen.1008967.ref050" target="_blank">50</a>–<a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1008967#pgen.1008967.ref052" target="_blank">52</a>].…”

Hematoxylin and eosin (H&E) and picrosirius red staining of LV-shRNA-ADAMTS-1 transduced vessels have increased lumen vessel area with decreased collagen expression. by Evelyn C. Nieves Torres (551495)

“…<b>A</b>) <b>Lower panel</b> is representative polarized light microscopy of picrosirius red-stained venous stenosis showing decreased fibrosis (collagen fibers are bright yellow) of the <b>LV</b> and <b>C</b> transduced vessels. …”

TrpA1 activation fails to enhance the increase in synaptic bouton number and axon branching conferred by <i>atl</i> loss. by Saurabh Srivastav (9585817)

The initiation region/matrix attachment region (IR/MAR) increased the homogeneously staining region (HSR) elongation rate and decreased the frequency of micronuclei after elevation... by Shun-suke Tanaka (604228)

Summary of cell-based assay EC50 results for WT BMP9 and A347E variant. by Tobias G. Schips (21799838)

A representative PCV case of 83 years old man with a 95-month treatment period and 27-month persistent fluid. by Chang-Chi Weng (8362725)

FldP decreases the H₂O₂-induced mutation frequency in <i>mutT</i>-deficient <i>P. aeruginosa</i>. by Alejandro J. Moyano (186752)

Results of two-way repeated measure ANOVAs for various HRV indicators. by Duyan Geng (12072181)

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Tension ratings at different period under taVNS or staVNS. by Duyan Geng (12072181)

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Descriptive statistics of HRV indicators among the three recordings (baseline, stimulation, recovery) under taVNS or staVNS conditions. by Duyan Geng (12072181)

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Descriptive statistics of Stimulation intensity, pain ratings and tension ratings under different stimulation conditions. by Duyan Geng (12072181)

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Differences in stimulation intensity between various parameters. by Duyan Geng (12072181)

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Procedure for study 1. by Duyan Geng (12072181)

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Stimulation response by parameter over time. by Duyan Geng (12072181)

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