<i>skn-1b</i> is not required for WT or <i>daf-2</i> longevity A-F) Survival of WT and <i>skn-1b</i> mutants in the absence and presence of <i>daf-2</i> mutation. by Nikolaos Tataridas-Pallas (10231350)

“…We conclude that <i>skn-1b</i> does not contribute to <i>daf-2</i> longevity. In a total of 15 trials (13 on OP50, 2 on HT115) bacteria we observed a slight decrease in <i>skn-1b</i> longevity compared to WT in 4 trials (<a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1009358#pgen.1009358.s004" target="_blank">S4</a> and <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1009358#pgen.1009358.s005" target="_blank">S5</a> Tables). …”

Table1_Pharmacokinetic herb-drug interactions: Altered systemic exposure and tissue distribution of ciprofloxacin, a substrate of multiple transporters, after combined treatment wi... by Ziqiang Li (247218)

“…</p><p>Results: Concurrent use of PCE substantially reduced circulating CIP (approximately 40%–50%) in humans and rats, while CIP hardly changed circulating GA and PCA. …”

Table2_Pharmacokinetic herb-drug interactions: Altered systemic exposure and tissue distribution of ciprofloxacin, a substrate of multiple transporters, after combined treatment wi... by Ziqiang Li (247218)

“…</p><p>Results: Concurrent use of PCE substantially reduced circulating CIP (approximately 40%–50%) in humans and rats, while CIP hardly changed circulating GA and PCA. …”

Presentation 1_Extraction of anthocyanins from purple sweet potato: evaluation of anti-inflammatory effects in a rheumatoid arthritis animal model, mechanistic studies on inflammat... by Jingjian Dong (12458730)

“…Molecular analysis showed reduced serum levels of inflammatory cytokines TNF-α, IL-1β, and rheumatoid factor (RF). In MH7A cells, PSPA decreased inflammatory cytokines (IL-1α, IL-6, IL-18), inhibited cell proliferation (IC50 = 1.43 μg/mL), and induced apoptosis by modulating Bcl-2, Bax, Caspase-3, and Caspase-9. …”

Table 1_Extraction of anthocyanins from purple sweet potato: evaluation of anti-inflammatory effects in a rheumatoid arthritis animal model, mechanistic studies on inflammatory cel... by Jingjian Dong (12458730)

“…Molecular analysis showed reduced serum levels of inflammatory cytokines TNF-α, IL-1β, and rheumatoid factor (RF). In MH7A cells, PSPA decreased inflammatory cytokines (IL-1α, IL-6, IL-18), inhibited cell proliferation (IC50 = 1.43 μg/mL), and induced apoptosis by modulating Bcl-2, Bax, Caspase-3, and Caspase-9. …”

Table 2_Extraction of anthocyanins from purple sweet potato: evaluation of anti-inflammatory effects in a rheumatoid arthritis animal model, mechanistic studies on inflammatory cel... by Jingjian Dong (12458730)

“…Molecular analysis showed reduced serum levels of inflammatory cytokines TNF-α, IL-1β, and rheumatoid factor (RF). In MH7A cells, PSPA decreased inflammatory cytokines (IL-1α, IL-6, IL-18), inhibited cell proliferation (IC50 = 1.43 μg/mL), and induced apoptosis by modulating Bcl-2, Bax, Caspase-3, and Caspase-9. …”

Table 3_Extraction of anthocyanins from purple sweet potato: evaluation of anti-inflammatory effects in a rheumatoid arthritis animal model, mechanistic studies on inflammatory cel... by Jingjian Dong (12458730)

“…Molecular analysis showed reduced serum levels of inflammatory cytokines TNF-α, IL-1β, and rheumatoid factor (RF). In MH7A cells, PSPA decreased inflammatory cytokines (IL-1α, IL-6, IL-18), inhibited cell proliferation (IC50 = 1.43 μg/mL), and induced apoptosis by modulating Bcl-2, Bax, Caspase-3, and Caspase-9. …”

<b>Data supporting the findings of Tian et al. (2024) </b><b>Multi-ecosystem services</b><b> differently affected by over-canopy and understory nitrogen additions in a typical subt... by yang tian (17858954)

“…Interestingly, the services of plant N, P retention and C sequestration exhibited a synergetic increase under the over-canopy N addition but a decrease under the understory N addition. …”

Data: Median heart rate per minute of motionless dolphins at surface from Towards non-invasive heart rate monitoring in free-ranging cetaceans: a unipolar suction cup tag measured... by Kagari Aoki (9994507)

“…Heart rate then gradually decreased at around 20–50 s and remained relatively constant until the next breath. …”

DataSheet_1_Precancerous Cervical Lesion Among Adult Women With Human Immune Deficiency Virus on Anti Retroviral Therapy At Saint Peter Specialized Hospital, Ethiopia: A Hospital-B... by Wondimu Zelalem (13152318)

“…Statistical significance was considered at a P-valve less than 0.05.</p>Result<p>A total of 267 women who were on ART were included in the study and the prevalence of precancerous cervical lesion was 7.5% with 95% CI =4.10%-10.50%. …”

Table_1_The Immunologic Effect of Early Intravenous Two and Four Gram Bolus Dosing of Tranexamic Acid Compared to Placebo in Patients With Severe Traumatic Bleeding (TAMPITI): A Ra... by Philip C. Spinella (5181788)

“…</p>Methods<p> This was a single center, double-blinded, randomized controlled trial (RCT) comparing placebo to a 2 g or 4 g intravenous TXA bolus dose in trauma patients with severe injury. …”

DataSheet1_Ginkgo Biloba Extract Is Comparable With Donepezil in Improving Functional Recovery in Alzheimer’s Disease: Results From a Multilevel Characterized Study Based on Clinic... by Yu Zheng (2950)

Table_1_Campylobacter Colonization, Environmental Enteric Dysfunction, Stunting, and Associated Risk Factors Among Young Children in Rural Ethiopia: A Cross-Sectional Study From th... by Dehao Chen (4966207)

“…<p>Livestock farming provides a possible mechanism by which smallholder farmers can meet their household need for animal source foods (ASF), which may reduce the risk of stunting. …”

mRNA expression of HO-1 (A), CXCL10 (B), and CXCR3 (C) in whole brain homogenates of control, ARM, ATV, ATV/ARM-treated<i> P. berghei</i>ANKA-infected mice (  = 5 per group). by Nana O. Wilson (399957)

Different Phenotypes of the Two Chinese Probands with the Same c.889G>A (p.C162Y) Mutation in <i>COCH</i> Gene Verify Different Mechanisms Underlying Autosomal Dominant Nonsyndromi... by Qi Wang (22418)

“…The results presented bilateral sensorineural hearing loss with a decreasing pattern, involving the low frequencies. …”

Maximum likelihood phylogeny inferred from an alignment of single-nucleotide polymorphisms present in the core genome of 937 isolates obtained from a subset of 3 studies of pneumoc... by Taj Azarian (659326)

Table_1_HLA-A*11:01:01:01, HLA-C*12:02:02:01-HLA-B*52:01:02:02, Age and Sex Are Associated With Severity of Japanese COVID-19 With Respiratory Failure.xlsx by Seik-Soon Khor (7244753)

“…After multivariate analysis controlling for other confounding factors and comorbidities, HLA-A*11:01:01:01 [P = 3.34E-03, OR = 3.41 (1.50–7.73)], age at diagnosis [P = 1.29E-02, OR = 1.04 (1.01–1.07)] and sex at birth [P = 8.88E-03, OR = 2.92 (1.31–6.54)] remained significant. …”

Image_2_The novel chimeric multi-agonist peptide (GEP44) reduces energy intake and body weight in male and female diet-induced obese mice in a glucagon-like peptide-1 receptor-depe... by James E. Blevins (11405813)

“…We hypothesized that GEP44 reduces energy intake and BW primarily through a GLP-1R dependent mechanism. To test this hypothesis, GLP-1R^+/+ mice and GLP-1R null (GLP-1R^-/-) mice were fed a high fat diet for 4 months to elicit diet-induced obesity prior to undergoing a sequential 3-day vehicle period, 3-day drug treatment (5, 10, 20 or 50 nmol/kg; GEP44 vs the selective GLP-1R agonist, exendin-4) and a 3-day washout. …”

Image_1_The novel chimeric multi-agonist peptide (GEP44) reduces energy intake and body weight in male and female diet-induced obese mice in a glucagon-like peptide-1 receptor-depe... by James E. Blevins (11405813)

“…We hypothesized that GEP44 reduces energy intake and BW primarily through a GLP-1R dependent mechanism. To test this hypothesis, GLP-1R^+/+ mice and GLP-1R null (GLP-1R^-/-) mice were fed a high fat diet for 4 months to elicit diet-induced obesity prior to undergoing a sequential 3-day vehicle period, 3-day drug treatment (5, 10, 20 or 50 nmol/kg; GEP44 vs the selective GLP-1R agonist, exendin-4) and a 3-day washout. …”

DataSheet1_Pharmacokinetic herb-drug interactions: Altered systemic exposure and tissue distribution of ciprofloxacin, a substrate of multiple transporters, after combined treatmen... by Ziqiang Li (247218)

“…</p><p>Results: Concurrent use of PCE substantially reduced circulating CIP (approximately 40%–50%) in humans and rats, while CIP hardly changed circulating GA and PCA. …”