Microtubule inhibitors cause cell cycle arrest and induce RKIP expression. by Saad Yousuf (541082)

“…Cells were harvested and washed twice with PBS and whole cell lysates were prepared for Western blot analysis as we have previously reported <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0092478#pone.0092478-AlMulla1" target="_blank">[28]</a>. …”

Artemisinin Inhibits Yeast Respiratory Growth by Depolarizing the Mitochondrial Membrane by Wei Li (7081)

“…The peak shift toward the left represents a decrease of fluorescence signal indicating the loss of membrane potential. …”

The probability of tumor nodule eradication increases with the increase of CTL number. by Claire Christophe (714134)

“…Other lines: same evolution when the mean killing time is decreased by 10%, 50% and 90%. …”

Mitochondrial fatty acid uptake and complex IV inhibition by palmitoylcarnitine in early type-2 diabetic hearts. by Phing-How Lou (198977)

“…N = 5–6 hearts per group. Data are or mean ± SD (panels A) or mean ± SEM (panel B).</p>…”

Overexpression of miR-105 inhibits tumour cell growth but does not induce apoptosis. by D. Rice Honeywell (442714)

“…<p>(A–B) Tumour cells were transfected with either 50 nM miR-105 (closed squares) or control (open circles) mimics and subsequently seeded into 96-well plates in replicates of 8. …”

Functional Lung Imaging during HFV in Preterm Rabbits by Jordan Thurgood (123527)

“…Whilst ventilated at fixed pressures, each animal was ventilated at frequencies of 1, 3, 5 and 10 Hz. A 50% decrease in delivered tidal volume was measured at 10 Hz compared to 1 Hz, yet at the higher frequency a 500% increase in minute activity was measured. …”

PTEN was the downstream target of miR-21 in inducing angiogenesis. by Ling-Zhi Liu (20849)

Leptin-induced relaxation of phenylephrine-preconstricted mesenteric artery rings in different experimental groups. by Anna Jamroz-Wiśniewska (514346)

“…EC₅₀– leptin concentration (ng/ml) which induced a half-maximal relaxation of PE-preconstricted segments. …”

Effects of AG-490 and WHI-P154 on nuclear translocation of STAT1α in IFN-γ-stimulated J774 macrophages by Outi Sareila (66176)

Effect of enzymatic complex in the diet of pirarucu, Arapaima gigas juveniles by Julliana de Castro LIMA (12678327)

“…The experimental design was randomized with four treatments [diets containing 0.25, 0.50, 0.75, and 1 g kg-1 on-top inclusion of an enzyme complex (Allzyme® SSF®, USA), and a control, with three replications at a density of 5 fish per unit, and a 30-day duration. …”

Characterization of phenotypically unique accessions. by Maria Stefania Przybylska (22756354)

“…</i></i> common accessions classification. Mean Decrease Accuracy (top) and Mean Decrease Gini (bottom) of the random forest models are presented. …”

Srp drives an overgrowth of the wing disc. by Kyra Campbell (582914)

“…Expression of <i>sna</i> results in a small, but significant decrease in wing disc size (B, D), whereas <i>srp</i> drives a large increase in the size of the GFP expressing compartment (C, D). …”

Antigenic evolution of viruses in host populations by Igor M. Rouzine (525036)

“…The fitness slope (effective selection coefficient) is proportional to the reproductive number in the absence of immunity <i>R</i>₀ and inversely proportional to the cross-immunity distance <i>a</i>, defined as the genetic distance of a virus strain from a previously infecting strain conferring 50% decrease in infection probability. …”

Overexpression of ST6GAL1 gene enhances the chemoresistance of K562 cells both in vitro and in vivo. by Hongye Ma (424073)

“…IC₅₀ represents the drug concentration producing 50% decrease of cell growth. …”

Immunoblotting of SHP in cisplatin-induced renal injury. by Eun Hui Bae (413566)

“…<p>SHP protein expression was reduced in cisplatin-induced renal injury mice, and it was attenuated by FXR ligand treatment (A). In HK-2 cells, SHP protein exhibited significantly decreased expression after cisplatin (50 µM, 16 h) treatment, and FXR ligand (20 µM, 1 h) pretreatment prevented this cisplatin-mediated decrease in SHP expression (B). …”

Cx43 distribution in CA3 after epileptiform activity. by Erika R. Kinjo (642091)

“…(B, C) Quantification of mean pixel intensity (n = 4 animals per group) showed significant increase in SP and decrease in SR in the acute period (E) compared to controls (D). …”

Antibiotic Prescription Patterns for Upper Respiratory Tract Infections in Outpatient Qatari Population in the Private Sector by Butt, Adeel Ajwad

“…Results: There were a total of 75,733 claims during the study period. …”
Get full text
Get full text

Telomerase mutant zebrafish have shorter telomeres than WT siblings. by Catarina M. Henriques (102294)

“…D) TRF mean sizes were calculated as described in <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1003214#pgen.1003214-Kimura1" target="_blank">[50]</a>. …”

ST266 attenuates RGC loss in mice with mild-moderate EAE optic neuritis. by Keirnan Willett (9946075)

“…(a) The average normalized RGC count across the entire retina shows a decrease in RGC numbers in vehicle-treated EAE mouse eyes (n = 22 eyes) compared to eyes from non-EAE control mice (n = 44 eyes) (*p<0.05). …”

Depletion of TGF-β alters morbidity in HK/486-infected mice. by Christina M. Carlson (240307)

“…<p>Six hours before infection, BALB/c mice were treated with a TGF-β neutralizing antibody (1D11) or an isotype control antibody (IgG) at a dose of 0.5 mg/mouse and subsequently inoculated with PBS (control) or 10⁵ TCID₅₀ units of HK/486 virus (n = 15). …”