The interplay between tauopathy and aging through interruption of UPR/Nrf2/autophagy crosstalk in the Alzheimer’s disease transgenic experimental models by Javad Amini (15446400)

“…</p> <p>Overall, we suggest that the neuropathological effects of tau aggregates may be accelerated brain aging, where redox signaling and autophagy efficacy play an important role.…”

Advancing Edge Speeds of Epithelial Monolayers Depend on Their Initial Confining Geometry - Fig 7 by Somanna A. Kollimada (3174168)

“…We see an increase in the speeds of cells from the cluster sides and vertices up to 8 hours (Phase I), a plateau region observed until 12 hours (Phase II), followed by a decrease in the cluster speeds by 16 hours (Phase III) B. …”

National trends in age-standardized mortality attributable to hypertension in Peru by Percy Herrera-Añazco (4259824)

“…Results: The age-standardized HTN mortality per 100,000 inhabitants decreased from 14.43 for the 2005 to 2010 period to 11.12 for the 2011 to 2016 period. …”

National trends in age-standardized mortality attributable to hypertension in Peru by Percy Herrera-Añazco (4259824)

“…Results: The age-standardized HTN mortality per 100,000 inhabitants decreased from 14.43 for the 2005 to 2010 period to 11.12 for the 2011 to 2016 period. …”

Oxygen concentration in the respiration chamber. by Pernille Nielsen (4249918)

“…Linear regression lines, regression equations and R² are given on the figure. The theoretical decrease in oxygen concentration in the respiration chamber (broken lines) calculated for the highest oxygen consumption (0.8 mg O₂ h^-1 g^-1) from literature ([<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0230176#pone.0230176.ref049" target="_blank">49</a>,<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0230176#pone.0230176.ref050" target="_blank">50</a>] and for the lowest (0.13 mg O₂ h^-1 g^-1) [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0230176#pone.0230176.ref048" target="_blank">48</a>].…”

CARDIOVASCULAR RESPONSES AFTER ISOMETRIC HANDGRIP EXERCISE AT DIFFERENT INTENSITIES IN HEALTHY MEN by Igor Marcelino da Silva (6674021)

“…None of the experimental sessions promoted statistically significant changes in systolic and diastolic BP (p> 0.05 for all). After S50, there was a smaller increase in SDNN five minutes after the exercise (S50: +5±6, S30: +20±5, SC: +10±2 ms, p <0.05) and higher LF/HF after 20 minutes (S50: +1.59±0.80, S30: -0.49±0.49, SC: +0.39±0.49, p <0.05) compared to the other sessions. …”

Creating an amplifier of weak selection for death-Birth updating. by Benjamin Allen (408337)

“…<p>(<b>A</b>) We begin with a 3-regular graph of size 12 in which all edges have weight 1. …”

Datasheet1_The clinical application of longitudinal layer specific strain as a diagnostic and prognostic instrument in ischemic heart diseases: A systematic review and meta-analysi... by Shreeya Sharma (14842921)

“…Endocardial LSS was found to be a good diagnostic marker for CAD in IHD patients (OR: 1.28, CI95% [1.11–1.48], p < 0.001, per 1% decrease). Epicardial (OR: 1.34, CI95% [1.14–1.56], p < 0.001, per 1% decrease), Mid-Myocardial (OR: 1.24, CI95% [1.12–1.38], p < 0.001, per 1% decrease) and endocardial (OR: 1.21, CI95% [1.09–1.35], p < 0.001, per 1% decrease) LSS all entailed diagnostic information regarding CAD, with epicardial LSS emerging as the superior diagnostic marker for CAD in patients with SAP. …”

S4 Dataset - by Shinichi Chisada (15354141)

“…Our results revealed that the medaka <i>rad50</i> mutation concurrently reproduced tumorigenesis (8 out of 10 <i>rad50</i>^<i>Δ2/+</i> medaka), had a decrease in median survival time (65.7 ± 1.1 weeks in control vs. 54.2 ± 2.6 weeks in <i>rad50</i>^<i>Δ2/+</i> medaka, <i>p</i> = 0.001, Welch’s <i>t</i>-test), exhibited semi-lethality in <i>rad50</i>^{<i>Δ2/Δ2</i>} medaka and most of the major ataxia-telangiectasia phenotypes, including ataxia (rheotaxis ability was lower in <i>rad50</i>^<i>Δ2/+</i> medaka than in the control, Mann–Whitney U test, <i>p</i> < 0.05), and telangiectasia (6 out of 10 <i>rad50</i>^<i>Δ2/+</i> medaka). …”

S3 Dataset - by Shinichi Chisada (15354141)

“…Our results revealed that the medaka <i>rad50</i> mutation concurrently reproduced tumorigenesis (8 out of 10 <i>rad50</i>^<i>Δ2/+</i> medaka), had a decrease in median survival time (65.7 ± 1.1 weeks in control vs. 54.2 ± 2.6 weeks in <i>rad50</i>^<i>Δ2/+</i> medaka, <i>p</i> = 0.001, Welch’s <i>t</i>-test), exhibited semi-lethality in <i>rad50</i>^{<i>Δ2/Δ2</i>} medaka and most of the major ataxia-telangiectasia phenotypes, including ataxia (rheotaxis ability was lower in <i>rad50</i>^<i>Δ2/+</i> medaka than in the control, Mann–Whitney U test, <i>p</i> < 0.05), and telangiectasia (6 out of 10 <i>rad50</i>^<i>Δ2/+</i> medaka). …”

S2 Dataset - by Shinichi Chisada (15354141)

“…Our results revealed that the medaka <i>rad50</i> mutation concurrently reproduced tumorigenesis (8 out of 10 <i>rad50</i>^<i>Δ2/+</i> medaka), had a decrease in median survival time (65.7 ± 1.1 weeks in control vs. 54.2 ± 2.6 weeks in <i>rad50</i>^<i>Δ2/+</i> medaka, <i>p</i> = 0.001, Welch’s <i>t</i>-test), exhibited semi-lethality in <i>rad50</i>^{<i>Δ2/Δ2</i>} medaka and most of the major ataxia-telangiectasia phenotypes, including ataxia (rheotaxis ability was lower in <i>rad50</i>^<i>Δ2/+</i> medaka than in the control, Mann–Whitney U test, <i>p</i> < 0.05), and telangiectasia (6 out of 10 <i>rad50</i>^<i>Δ2/+</i> medaka). …”

S5 Dataset - by Shinichi Chisada (15354141)

“…Our results revealed that the medaka <i>rad50</i> mutation concurrently reproduced tumorigenesis (8 out of 10 <i>rad50</i>^<i>Δ2/+</i> medaka), had a decrease in median survival time (65.7 ± 1.1 weeks in control vs. 54.2 ± 2.6 weeks in <i>rad50</i>^<i>Δ2/+</i> medaka, <i>p</i> = 0.001, Welch’s <i>t</i>-test), exhibited semi-lethality in <i>rad50</i>^{<i>Δ2/Δ2</i>} medaka and most of the major ataxia-telangiectasia phenotypes, including ataxia (rheotaxis ability was lower in <i>rad50</i>^<i>Δ2/+</i> medaka than in the control, Mann–Whitney U test, <i>p</i> < 0.05), and telangiectasia (6 out of 10 <i>rad50</i>^<i>Δ2/+</i> medaka). …”

Stable swimming of wildtype. by Shinichi Chisada (15354141)

“…Our results revealed that the medaka <i>rad50</i> mutation concurrently reproduced tumorigenesis (8 out of 10 <i>rad50</i>^<i>Δ2/+</i> medaka), had a decrease in median survival time (65.7 ± 1.1 weeks in control vs. 54.2 ± 2.6 weeks in <i>rad50</i>^<i>Δ2/+</i> medaka, <i>p</i> = 0.001, Welch’s <i>t</i>-test), exhibited semi-lethality in <i>rad50</i>^{<i>Δ2/Δ2</i>} medaka and most of the major ataxia-telangiectasia phenotypes, including ataxia (rheotaxis ability was lower in <i>rad50</i>^<i>Δ2/+</i> medaka than in the control, Mann–Whitney U test, <i>p</i> < 0.05), and telangiectasia (6 out of 10 <i>rad50</i>^<i>Δ2/+</i> medaka). …”

Unstable swimming of mutant. by Shinichi Chisada (15354141)

“…Our results revealed that the medaka <i>rad50</i> mutation concurrently reproduced tumorigenesis (8 out of 10 <i>rad50</i>^<i>Δ2/+</i> medaka), had a decrease in median survival time (65.7 ± 1.1 weeks in control vs. 54.2 ± 2.6 weeks in <i>rad50</i>^<i>Δ2/+</i> medaka, <i>p</i> = 0.001, Welch’s <i>t</i>-test), exhibited semi-lethality in <i>rad50</i>^{<i>Δ2/Δ2</i>} medaka and most of the major ataxia-telangiectasia phenotypes, including ataxia (rheotaxis ability was lower in <i>rad50</i>^<i>Δ2/+</i> medaka than in the control, Mann–Whitney U test, <i>p</i> < 0.05), and telangiectasia (6 out of 10 <i>rad50</i>^<i>Δ2/+</i> medaka). …”

Use of thermography to guide amputation levels. by Mario Aurelio Martínez-Jiménez (5963564)

“…<p>Thermographic imaging can be used as an adjunct to determine amputation levels in severely burned patients. A 24-year old patient with fourth degree burns in approximately 50% of his body surface area because of direct fire was admitted to the burn unit (A). …”

bpV(pic) reduces neuronal autophagosome aggregation. by Chandler L. Walker (188845)

“…Treatment with bpV promoted a decrease in neuronal autophagosome clustering. …”

Effect of crizotinib and alectinib on stimulus preference of retinal ganglion cells. by Toshiyuki Ishii (53332)

“…<p>(A and B) Post-stimulus time histogram before (pre), during (crizotinib), and after (wash) the application of 1.0μM of crizotinib in an OFF-cell (A) and in an ON-OFF cell (B). …”

MO-SAM segmentation performance using the Grid method in arid/semi-arid landscape. by Qitong Wang (15279695)

“…The point prompts, annotations, pixel intervals, and predictions are shown in light blue and the PI is 50, 35, 20; the IoU scores from left to right are 83.99, 81.05, and 44.19 percent, indicating a decrease in performance as the number and density of gridded point prompts increases In the third row, Platinum Group Elements, the point prompts, annotations, pixel intervals, and predictions are shown in purple. …”

Age-dependent changes in biometrics indicate senescence in the European Blackbird <i>Turdus merula</i> by Piotr Piliczewski (5277803)

“…<p><b>Capsule:</b> A 19-year study of European Blackbirds <i>Turdus merula</i> confirms that senescence is associated with a decrease in condition measured by wing length but bills become progressively longer with age.…”

MPA gap analysis results based upon alternate choices of datasets. by Casey C. O'Hara (3997529)

“…Scenario 3, still using 2015 AquaMaps data, drops the presence threshold to zero, showing an expected decrease in gap species, but also a decrease in species with 5% or greater protected range. …”