The S75A mutation of LeishIF4E3 leads to a decrease in granule formation in response to PBS starvation and to a reduced interaction with LeishIF4G-4. by Rohit Shrivastava (6459608)

IDD388 Polyhalogenated Derivatives as Probes for an Improved Structure-Based Selectivity of AKR1B10 Inhibitors by Alexandra Cousido-Siah (777034)

“…Next, by means of IC₅₀ measurements, X-ray crystallography, WaterMap analysis, and advanced binding free energy calculations with a quantum-mechanical (QM) approach, we have studied their structure–activity relationship (SAR) against both enzymes. …”

TF YF-to-S mutants decrease hyphal-specific gene expression. by Collin Ganser (8924843)

Data Sheet 1_Reduced hemolytic complement activity in the classical pathway (CH50) is a risk factor for poor clinical outcomes of patients with infections: a retrospective analysis... by Hiroyuki Koami (3878434)

“…</p>Results<p>Of 2,726 patients who met the inclusion criteria, logistic regression models demonstrated that decreased CH50 is a significant predictor of 180-day mortality (OR: 0.98-0.99). …”

<i>Gnas</i> deletion in hypothalamic <i>Opn5</i> neurons. by Kevin D. Gaitonde (15411707)

Conditional suppression of p21 enhances proliferation of WT NPC. by Robert N. Pechnick (340285)

A heat map was generated for all the miRs utilized in the array, as a function of a fold change from referent control values. by Stephanie L. Samani (17896610)

Telomerase mutant zebrafish have shorter telomeres than WT siblings. by Catarina M. Henriques (102294)

“…D) TRF mean sizes were calculated as described in <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1003214#pgen.1003214-Kimura1" target="_blank">[50]</a>. …”

A Minor (<50%) Signet-Ring Cell Component Associated with Poor Prognosis in Colorectal Cancer Patients: A 26-Year Retrospective Study in China by Yinuo Tan (705777)

“…<div><p>Background</p><p>We performed a retrospective study to determine the cancer-specific survival of colorectal cancer patients with a component of signet-ring cells or mucin comprising < 50% of the tumor mass.…”

Movie 2 Rik^null vs. WT. by Erdyni N. Tsitsikov (20384719)

Root cell wall proteins with significant decreased in expression level under 50 µM Cu treatment identified by LC-ESI-MS/MS-based proteomics using SIEVE (<i>p</i><0.05 and fold chan... by Tingting Liu (267387)

“…</p><p>Root cell wall proteins with significant decreased in expression level under 50 µM Cu treatment identified by LC-ESI-MS/MS-based proteomics using SIEVE (<i>p</i><0.05 and fold chang >1.5).…”

Redox and methylation metabolite and cobalamin status in GCLM KO mice. by Yiting Zhang (391974)

IFNγ increases PRL immunoreactivity in the hair follicle, whilst TNFα decreases follicular PRL immunoreactivity. by Ewan A. Langan (405804)

“…<p>(A) PRL IR in control hair follicle outer root sheath keratinocytes (black arrows), (B) after INFγ treatment and (C) negative control. …”

A) Exemplary relative quantification of AUREO1a concentration in protein extracts of <i>P. tricornutum</i> WT, <i>aureo1a-15</i> and <i>aureo1a-50</i> by an immunoblot using an ant... by Benjamin Schellenberger Costa (461158)

Anti-cancer stem cell activity of a sesquiterpene lactone isolated from <i>Ambrosia arborescens</i> and of a synthetic derivative by Wendy Soria Sotillo (4408105)

“…Inhibitory concentration 50 (IC₅₀) values were obtained from dose-response curves. …”

Axonal transport effects, APP labeling with losartan-treated vs water control. by Harry A. Quigley (695817)

Proteins in thyroid tissue with differential expression levels above or below 1.5 for all activity groups (0.5, 5, 50 and 500 kBq) (totally 133 proteins). by Malin Larsson (1616557)

FRET signals in myotubes expressing CFP-CCXXCC and WT CFP. by Dipankar Bhattacharya (485340)

“…After 2 hrs of incubation in 1 μM FlAsH to load the tetracysteine motif, fluorescence in the CFP channel decreased and in the FLUO channel increased (green circle, middle panel). …”

Mean seedling length of mung bean genotypes grown under Cd and pretreatments of GA₃, SA and proline prior to Cd. by Meher Hassan (11502144)

Mean total protein contents of mung bean grown under Cd and pretreatments of GA₃, SA and proline prior to Cd. by Meher Hassan (11502144)