Effect of Gen/Rev on As₂O₃-induced cell viability of NB4 cells and NRLVMs (n = 6). by Yuhua Fan (180523)

“…<p>Co-treatment of 5 µM Rev or 50 µM Gen further decreased the cell viability of NB4 cells (A, C) but reversed the cell viability of NRLVMs (B, D). …”

Co-immunoprecipitation of TDP-43 and TIA-1. by Liqun Liu-Yesucevitz (240136)

“…The lysates were treated with RNase A (50 µg/ml) for 30 min at 37°C. Immunoprecipitated was performed with antibody to TIA-1, and the immunoblots were probed with antibody to TDP-43. …”

Image_1_Inhibited Carnitine Synthesis Causes Systemic Alteration of Nutrient Metabolism in Zebrafish.JPEG by Jia-Min Li (1452607)

“…Liver TG concentrations increased by more than 50% in mildronate-treated fish. Mildronate decreased the efficiency of liver mitochondrial β-oxidation, increased the hepatic mRNA expression of genes related to FA β-oxidation and lipolysis, and decreased the expression of lipogenesis genes. …”

Table_1_Inhibited Carnitine Synthesis Causes Systemic Alteration of Nutrient Metabolism in Zebrafish.DOC by Jia-Min Li (1452607)

“…Liver TG concentrations increased by more than 50% in mildronate-treated fish. Mildronate decreased the efficiency of liver mitochondrial β-oxidation, increased the hepatic mRNA expression of genes related to FA β-oxidation and lipolysis, and decreased the expression of lipogenesis genes. …”

Image_2_Inhibited Carnitine Synthesis Causes Systemic Alteration of Nutrient Metabolism in Zebrafish.JPEG by Jia-Min Li (1452607)

“…Liver TG concentrations increased by more than 50% in mildronate-treated fish. Mildronate decreased the efficiency of liver mitochondrial β-oxidation, increased the hepatic mRNA expression of genes related to FA β-oxidation and lipolysis, and decreased the expression of lipogenesis genes. …”

Excretion in acoelomorphs. by Carmen Andrikou (7053542)

“…Error bars indicate minimum and maximum of the biological replicates (averaged technical replicates). A 1-fold change represents no change; ≥2 indicates significantly increased expression level; ≤0.5 indicates significantly decreased expression level (red labels). …”

DataSheet_1_Mitochondrial dysfunction and metabolic reprogramming induce macrophage pro-inflammatory phenotype switch and atherosclerosis progression in aging.pdf by Aleksandr E. Vendrov (18861325)

Increased glycolytic flux in <i>dcerk¹</i> compared to <i>w¹¹¹⁸</i> due to activation of Pglym and downstream glycolytic enzymes through AKT. by Niraj K. Nirala (424266)

“…For visualizing tGPH in fat body, 15–20 early third instar larvae were used in each experiment and three independent experiments were carried out. Scale bar represents 50 µm. (D). FOXO transcript level is measured by QPCR and shows a 60% reduction in in <i>dcerk¹</i> flies compared to <i>w¹¹¹⁸</i>. …”

Ultrasensitive dependence of the overall elongation rate on EF-Tu concentration in <i>E. coli</i>. by Sophia Rudorf (169011)

“…If the EF-Tu concentration is reduced by 15% (orange dashed line), the overall elongation rate strongly decreases by about 50%. When 20% of all EF-Tu molecules are inhibited (red dashed line), a critical EF-Tu concentration is reached, at which protein synthesis is almost completely suppressed. …”

Table 1_Impact of catheter-to-vein diameter ratio on thrombosis in pediatric central venous catheterization.pdf by Fevzi Kahveci (15121585)

“…In our study, thrombosis risk factors and patient-related factors were excluded.</p>Results<p>A total of 50 patients were included in our study. …”

Glycosylated Platinum(IV) Complexes as Substrates for Glucose Transporters (GLUTs) and Organic Cation Transporters (OCTs) Exhibited Cancer Targeting and Human Serum Albumin Binding... by Jing Ma (24574)

“…Glycosylated platinum­(IV) complexes <b>5</b>, <b>6</b>, <b>7</b>, and <b>8</b> (IC₅₀ 0.24–3.97 μM) had better antitumor activity of nearly 166-fold higher than the positive controls cisplatin (<b>1a</b>), oxaliplatin (<b>3a</b>), and satraplatin (<b>5a</b>). …”

Characteristics of <i>EGFR</i> Mutant Cell Lines. by Jeet Gandhi (262339)

“…<p><a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0004576#pone-0004576-t003" target="_blank">Table 3</a> shows the clinico-pathologic and molecular data for the 10 NSCLC cell lines, which harbor <i>EGFR</i> mutations. …”

Supplementary Material for: Role of Aquaporin-5 in Gallbladder Carcinoma by Sekine S. (4142311)

“…On the other hand, those cells increased IC₅₀ of gemcitabine. By performing miRNA assays, miR-29b, -200a, and -21 were shown to be highly overexpressed in cells treated with AQP-5 siRNA NOZ. …”

Barium Promotes Anchorage-Independent Growth and Invasion of Human HaCaT Keratinocytes via Activation of c-SRC Kinase by Nguyen Dinh Thang (201359)

“…Barium (5 µM) biochemically enhanced activities of c-SRC, FAK, ERK and MT1-MMP molecules, which regulate anchorage-independent growth and/or invasion. A SRC kinase specific inhibitor, protein phosphatase 2 (PP2), blocked barium-mediated promotion of anchorage-independent growth and invasion with decreased c-SRC kinase activity. …”

Accumulation of Su(H) mutant protein depends on both H and Notch. by Heiko Praxenthaler (489179)

“…<b>(A)</b> Su(H) protein accumulation is decreased specifically within the H-RNAi domain (arrowhead), whereas Cut expression appears normal. …”

Glycosylated Platinum(IV) Complexes as Substrates for Glucose Transporters (GLUTs) and Organic Cation Transporters (OCTs) Exhibited Cancer Targeting and Human Serum Albumin Binding... by Jing Ma (24574)

“…Glycosylated platinum­(IV) complexes <b>5</b>, <b>6</b>, <b>7</b>, and <b>8</b> (IC₅₀ 0.24–3.97 μM) had better antitumor activity of nearly 166-fold higher than the positive controls cisplatin (<b>1a</b>), oxaliplatin (<b>3a</b>), and satraplatin (<b>5a</b>). …”

Optimization of Control Strategies for Non-Domiciliated <em>Triatoma dimidiata</em>, Chagas Disease Vector in the Yucatán Peninsula, Mexico by Corentin Barbu (221439)

“…Pyrethroid spraying was found effective when 50 mg/m² were applied yearly within a two-month period matching the immigration season. …”

Exemplar task-related activity across recording days. by David T. Bundy (7586414)

“…</b> Multi-unit firing rates were estimated by counting spike times within a 100 ms window shifted by 50 ms between windows and then averaging firing rates across trials, showing a statistically significant (p<0.05) increase in firing rate aligned to the grasp. …”

<b>Complex relationship between habitat extent and fragmentation in recovering landscapes: The case of the giant panda</b> by Andrés Viña (3120402)

“…Although this complexity has important consequences for conservation, it has predominantly been evaluated empirically in landscapes exhibiting habitat loss, not in recovering landscapes, and mostly at a single scale. Using the recovery of the habitat of a global conservation icon (giant pandas, Ailuropoda melanoleuca) as a demonstration, we empirically examined the complexity of the relationship between habitat extent and fragmentation from the perspective of habitat recovery. …”

Table_1_Novel myeloma patient-derived xenograft models unveil the potency of anlotinib to overcome bortezomib resistance.docx by Yanhua Yue (4962670)

“…<p>Multiple myeloma (MM) remains a common hematologic malignancy with a 10-year survival rate below 50%, which is largely due to disease relapse and resistance. …”