TNNI3K expression leads to premature death in the <i>Csq</i> transgenic model of cardiomyopathy. by Ferrin C. Wheeler (259443)

“…Survival is severely decreased for double positive transgenics (<i>TNNI3K^tg</i>/<i>Csq^tg</i>) to an average of 17 days with a range from 15 to 21 days. …”

Future Mangrove Carbon Storage Under Climate Change and Deforestation by Chatting, Mark

“…Projecting current mangrove deforestation rates into the future resulted in a total of 678.50 ± 151.32 Tg CO2e emitted from 2012 to 2095. …”
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Pollen-based Holocene vegetation reconstruction.xlsx by Yuanhao Sun (12697028)

“…In the Daihai basin, the vegetation cover changed relatively little, maintaining values of 45–50%, and only increased during the interval of 8–5.1 ka, when it attained a maximum of 67%. …”

Table1_Anti-hyperglycemic effects of Cissus quadrangularis extract via regulation of gluconeogenesis in type 2 diabetic db/db mice.DOCX by Jeong-Won Kim (18464976)

“…In this study, the therapeutic effects of C. quadrangularis extract (CQR-300) on type 2 diabetes mellitus (T2DM) were investigated in a leptin receptor-mutated db/db mouse model.</p><p>Methods: CQR-300 was orally administered to db/db mice (n = 6/group) at different doses (50, 100, and 200 mg/kg) for 8 weeks. …”

Datasheet1_Diagnostic and prognostic value of an ejection fraction adjusted for myocardial remodeling.docx by Wei Xuan Chan (11949866)

“…Both low EF and low EFa were associated with a high HF readmission risk. However, in the cohort with a normal EF (EF ≥ 50%), models using EFa were significantly more associative with HF readmissions within 3 years, where the leave one out cross validation ROC analysis showed a 18.6% reduction in errors, and Net Classification Index (NRI) analysis showed that risk increment classification of events increased by 12.2%, while risk decrement classification of non-events decreased by 16.6%.…”

Supplementary Material for: Postoperative Acute Kidney Injury: Focus on Renal Recovery Definitions, Kidney Disease Progression and Survival by Long T.E. (6276614)

“…Risk of incident and progressive CKD within 5 years was significantly increased if patients did not achieve a reduction in SCr to < 1.5 × baseline (hazard ratio [HR] 1.50; 95% CI 1.29–1.75) and if renal recovery was limited to a fall in SCr to 1.25–1.5 × baseline (HR 1.32; 95% CI 1.12–1.57) within 30 days. …”

Conditional knockout and genotyping strategies. by Ping Xu (122619)

“…(D) As determined by qPCR, <i>Rfx4</i> mRNA levels were decreased by approximately 50% (P< 0.01, n = 4) in the brains of <i>Rfx4</i><b><i>^+/-</i></b> mice, as determined by fold changes after normalizing with <i>Gapdh</i> mRNA. …”

pH sensitive lipid polymeric hybrid nanoparticle (LPHNP) of paclitaxel and curcumin for targeted delivery in breast cancer by Hrishikesh Sarma (14827761)

“…MTT-assay studies revealed enhanced cytotoxicity of CUR and PTX as LPHNPs showing IC₅₀ value of free CUR & PTX 480.06 µg/mL decreasing to 282.97 µg/mL for CS-CUR-PTX-LPHNPs. …”

Table_1_Reassessing Particulate Organic Carbon Dynamics in the Highly Disturbed San Francisco Bay Estuary.XLSX by Peter J. Hernes (8640351)

“…Lignin compositional data (syringyl:vanillyl and cinnamyl:vanillyl) suggest that increased lignin content in the more saline samples could be derived from wetland materials, while a two-endmember mixing model indicates that a significant portion of the particulate organic carbon (POC) in the western sites (50–60% as an upper bound, 13–15% as a lower bound) could be wetland-derived. …”

Table_2_Reassessing Particulate Organic Carbon Dynamics in the Highly Disturbed San Francisco Bay Estuary.XLSX by Peter J. Hernes (8640351)

“…Lignin compositional data (syringyl:vanillyl and cinnamyl:vanillyl) suggest that increased lignin content in the more saline samples could be derived from wetland materials, while a two-endmember mixing model indicates that a significant portion of the particulate organic carbon (POC) in the western sites (50–60% as an upper bound, 13–15% as a lower bound) could be wetland-derived. …”

Gene expression profiles in wildtype, <i>Tnfr1</i>- and <i>Tnfr2-</i>deficient glomeruli after TNF stimulation ex vivo. by Anela Taubitz (433585)

“…<p>Expression profiling by microarrays was performed on isolated glomeruli from wildtype, <i>Tnfr1</i>−/− and <i>Tnfr2</i>−/− mice 12 after stimulation with 50 ng/ml TNF for 12 hours ex vivo. A negativ “fold change” (black to green) indicates decreased expression and a postive “fold change” (black to red) indicates increased expression in a glomerular sample compared with the average of all analyzed samples. …”

Datasheet1_Diagnostic and prognostic value of an ejection fraction adjusted for myocardial remodeling.docx by Wei Xuan Chan (11949866)

“…Both low EF and low EFa were associated with a high HF readmission risk. However, in the cohort with a normal EF (EF ≥ 50%), models using EFa were significantly more associative with HF readmissions within 3 years, where the leave one out cross validation ROC analysis showed a 18.6% reduction in errors, and Net Classification Index (NRI) analysis showed that risk increment classification of events increased by 12.2%, while risk decrement classification of non-events decreased by 16.6%.…”

Image1_Anti-hyperglycemic effects of Cissus quadrangularis extract via regulation of gluconeogenesis in type 2 diabetic db/db mice.TIF by Jeong-Won Kim (18464976)

“…In this study, the therapeutic effects of C. quadrangularis extract (CQR-300) on type 2 diabetes mellitus (T2DM) were investigated in a leptin receptor-mutated db/db mouse model.</p><p>Methods: CQR-300 was orally administered to db/db mice (n = 6/group) at different doses (50, 100, and 200 mg/kg) for 8 weeks. …”

Presentation1_Anti-hyperglycemic effects of Cissus quadrangularis extract via regulation of gluconeogenesis in type 2 diabetic db/db mice.PPTX by Jeong-Won Kim (18464976)

“…In this study, the therapeutic effects of C. quadrangularis extract (CQR-300) on type 2 diabetes mellitus (T2DM) were investigated in a leptin receptor-mutated db/db mouse model.</p><p>Methods: CQR-300 was orally administered to db/db mice (n = 6/group) at different doses (50, 100, and 200 mg/kg) for 8 weeks. …”

Image2_Anti-hyperglycemic effects of Cissus quadrangularis extract via regulation of gluconeogenesis in type 2 diabetic db/db mice.TIF by Jeong-Won Kim (18464976)

“…In this study, the therapeutic effects of C. quadrangularis extract (CQR-300) on type 2 diabetes mellitus (T2DM) were investigated in a leptin receptor-mutated db/db mouse model.</p><p>Methods: CQR-300 was orally administered to db/db mice (n = 6/group) at different doses (50, 100, and 200 mg/kg) for 8 weeks. …”

Data_Sheet_1_Differentiated Mechanisms of Biochar Mitigating Straw-Induced Greenhouse Gas Emissions in Two Contrasting Paddy Soils.docx by Ya-Qi Wang (585856)

“…Results showed that straw addition markedly increased the cumulative CH₄ emissions in both soils by 4.7- to 9.1-fold and 23.8- to 72.4-fold at low (S1) and high (S2) straw input rate, respectively, and significantly increased mcrA gene abundance. Biochar amendment under the high straw input (BS2) significantly decreased CH₄ emissions by more than 50% in both soils, and increased both mcrA gene and pmoA gene abundances, with greatly enhanced pmoA gene and a decreased mcrA/pmoA gene ratio. …”

Frequency-dependent activation in NF trabeculae (<i>n</i> = 9) vs. failing trabeculae with no hypothyroidism (FNH; <i>n</i> = 9) and failing trabeculae with hypothyroidism (FH; <i>... by Nancy S. Saad (2615341)

“…<b>(D)</b> TTP shortened upon increasing frequency of stimulation in all groups with no differences between NF and both failing groups at each respective frequency. <b>(E)</b> RT50 decreased as frequency increased from 0.5 Hz to 3 Hz in all three groups. …”

PCL/ZnO Bio-friendly Films as Food Packaging Material.Thermal and morphological analysis by Rivaildo Miranda de Andrade (6070211)

“…The addition of ZnO to PCL decreased the degradation temperature about 50-70°C; the films are thermally stable up to 200°C, making them suitable for packaging hot grilled chicken. …”

Optimizing nitrogen application rate and plant density for improving cotton yield and nitrogen use efficiency in the North China Plain by Pengcheng Li (123281)

“…The main plots were PPDs (plants m⁻²) of 3.00 (low), 5.25 (medium) and 7.50 (high) and the subplots were NARs of 0 (N-free), 112.5 (low), 225.0 (moderate) and 337.5 (high). …”

Effects of Maraviroc and Efavirenz on Markers of Immune Activation and Inflammation and Associations with CD4⁺ Cell Rises in HIV-Infected Patients by Nicholas Funderburg (89116)

“…term=MERIT&cond=HIV&rank=1">NCT00098293</a></p></div>…”