Regional plots of replicated DMRs. by Peter Henneman (174625)

“…<b>Tracks:</b> <i>CpG</i>: localization of CpG sites (UCSC, HG19), <i>RefGen</i>: Reference gene, blocks represents exonic regions, arrow indicates direction of transcription (UCSC, HG19), <i>CpG island</i>: blocks represent the localization of CpG islands (> 300bp, GC content > 50%, ratio observed/expected CpG > 0,6). <i>K562 H3k27me3</i>: histone 3 lysine 27 3 methylation mark in K562 (chronic myelogenous leukemia human cell line, gain of the mark is associated with decreased activity of gene). …”

DataSheet2_Frutescone O from Baeckea frutescens Blocked TLR4-Mediated Myd88/NF-κB and MAPK Signaling Pathways in LPS Induced RAW264.7 Macrophages.PDF by Xiaobing Lin (4257988)

“…., which was commonly used as a folk medicinal material for treating anti-inflammatory disease in South East Asia. …”

Enhancing both oral bioavailability and brain penetration of puerarin using borneol in combination with preparation technologies by Tao Yi (504558)

“…The pharmacokinetics results indicated borneol with doses of over 50 mg/kg could obviously increase both intestinal absorption and brain penetration of puerarin. …”

Data_Sheet_1_The Protective Effect of Sulforaphane on Dextran Sulfate Sodium-Induced Colitis Depends on Gut Microbial and Nrf2-Related Mechanism.doc by Canxia He (12961379)

“…This study's findings suggest that SFN may serve as a therapeutic agent protecting against UC.</p>…”

DataSheet1_Frutescone O from Baeckea frutescens Blocked TLR4-Mediated Myd88/NF-κB and MAPK Signaling Pathways in LPS Induced RAW264.7 Macrophages.CDX by Xiaobing Lin (4257988)

“…., which was commonly used as a folk medicinal material for treating anti-inflammatory disease in South East Asia. …”

Synthesis and Apoptotic Effects of DNMT Inhibition Targeted Novel Hybrid Molecules Bearing Thiadiazole and Clopidogrel for Cancer Treatment by Sevgi Karakuş (9731958)

“…DNMT enzyme activity was decreased in these compounds’ treated cells. Cyclohexyl ring-bearing compound <b>4d</b>, which showed the highest activity against U87 cells, was the most potent inhibitor of DNMT with an IC₅₀ value of 5.78 ± 1.07 µM compared to paclitaxel (82.05 ± 4.67 µM). …”

Effect of Dietary Supplementation of Full-Fat Canola Seeds on Productive Performance, Blood Metabolites and Antioxidant Status of Laying Japanese Quails by NS Ibrahim (10446819)

“…<div><p>ABSTRACT The present study was carried out to evaluate the effects of dietary supplementation of different levels of full-fat canola seeds (FFCS) on productive performance, blood metabolites and antioxidant status of laying Japanese quails. A total of 360, 8-week-old quails were divided into a completely randomize design with 4 dietary experimental groups and three pens each, each pen containing 30hens. …”

Data_Sheet_1_Microbiota of vaccinated and non-vaccinated clinically inconspicuous and conspicuous piglets under natural Lawsonia intracellularis infection.docx by Julia Hankel (3932024)

“…<p>Lawsonia (L.) intracellularis is a widespread, economically important bacterium causing the porcine proliferative enteropathy (PPE). …”

Blunted excitability of aortic baroreceptor neurons in diabetic rats: involvement of hyperpolarizationactivated channel by Yu-Long Li (311230)

“…<strong>Methods and results:</strong> Using the whole-cell patch clamp technique, we found that AB neuron excitability (action potential frequency at 50 pA current stimulation) in the T1D rats was lower than that in the sham rats (0.4 ± 0.5 vs. 4.8 ± 0.6 spikes/sec, p<0.05; AB neurons were identified by DiI staining). …”

Evaluation of Immunological Parameters in Pregnant Women: Low Levels of B and NK Cells by Juliana Araújo de Carvalho Schettini (6878852)

“…<div><p>Abstract Objective To describe the immunological and hematological reference intervals of low-risk pregnant women. Methods A cross-sectional retrospective database analysis of a basic and translational study analyzing the hematological evaluation blood counts and immunophenotyping of TCD3 + , TCD4 + , TCD8 + , B, and natural killer (NK) cells of the peripheral blood in 79 low-risk pregnant women and of 30 control women from the state of Pernambuco, Brazil, was performed. …”

Table1_Effect of Velocity and Contact Stress Area on the Dynamic Behavior of the Spinal Cord Under Different Testing Conditions.pdf by Chen Jin (703369)

“…Additionally, the cord became stiffer (i.e., increasing elastic modulus) and softer (i.e., decreasing elastic modulus) at a higher velocity and larger contact stress area, respectively. …”

Supplementary Material for: Walnuts (Seeds of <b><i>Juglandis</i></b> <b><i>sinensis</i></b> L.) Protect Human Epidermal Keratinocytes against UVB-Induced Mitochondria-Mediated Apo... by Park G. (4141492)

“…Walnuts, the seeds of <i>Juglandis</i><i>sinensis</i> L., are a highly nutritious food and have been shown to have a number of pharmacological activities. …”

DataSheet3_Effect of Velocity and Contact Stress Area on the Dynamic Behavior of the Spinal Cord Under Different Testing Conditions.PDF by Chen Jin (703369)

“…Additionally, the cord became stiffer (i.e., increasing elastic modulus) and softer (i.e., decreasing elastic modulus) at a higher velocity and larger contact stress area, respectively. …”

Low magnitude high frequency vibration promotes adipogenic differentiation of bone marrow stem cells via P38 MAPK signal by Qian Zhao (217607)

“…After treating cells with SB203580, a specific p38 inhibitor, both the protein level of PPARγ illustrated by immunofluorescent staining and the oil droplets number, were decreased. …”

dpp transcription is repressed by Egfr signaling during DC. by Weiping Shen (400583)

“…<p>Panels A, C, E and F are digoxigenin <i>in situ</i> hybridizations and panels B, D and H–H´ ´ are FISH, with all embryos at beginning of DC. …”

Flask and reactor scale production of plant growth regulators by <i>Inonotus hispidus</i>: optimization, immobilization and kinetic parameters by Bilal Doğan (16495833)

“…<p>The aims of the presented study are to compare submerged, static, and solid-state fermentation in the production of gibberellic acid (GA₃), indole acetic acid (IAA), and abscisic acid (ABA) by <i>Inonotus hispidus</i>, to optimize with a statistical approach, and to determine the kinetic parameters under flask and reactor conditions. …”

2‑Ethylhexyl Diphenyl Phosphate and Its Hydroxylated Metabolites are Anti-androgenic and Cause Adverse Reproductive Outcomes in Male Japanese Medaka (Oryzias latipes) by Yu Li (183836)

“…In this study, we for the first time observed that EHDPP elicited androgen receptor (AR) antagonistic activity with a 50% inhibitory concentration of 37.5 μM. 2-Ethyl-5-hydroxyhexyl diphenyl phosphate was proved to be the dominant metabolite of EHDPP in Japanese medaka and elicited 3.1-fold stronger AR antagonistic activity than that of EHDPP. …”

Resistance and tolerance: the role of nutrients on pathogen dynamics and infection outcomes in an insect host by Charlotte Miller (4410157)

“…The dose required to kill 50% of individuals in this species was several magnitudes higher than in other species and the bacteria were shown to display massive decreases in population size, in contrast to patterns of proliferation found in other host species. …”

High glucose induces pyroptosis of retinal microglia through NLPR3 inflammasome signaling by Libin Huang (124637)

“…Results: High-glucose (25, 50, or 100 mM) stimulation decreased cell viability, but enhanced lactate dehydrogenase release and caspase-1 activity in a dose-dependent manner. …”

Expression and Polymorphism of Toll-Like Receptor 4 and Effect on NF-κB Mediated Inflammation in Colon Cancer Patients by Abdelhabib Semlali (291393)

“…In contrast, the <i>rs2770150</i> is associated with colon cancer in women aged over 50 years and is closely linked with the decreased levels of female sex hormones during the post-menopausal period (OR = 0.188, CI: 0.074–0.48, P = <0.00084). …”