The Expression of TBC1 Domain Family, Member 4 (TBC1D4) in Skeletal Muscles of Insulin-Resistant Mice in Response to Sulforaphane by Rizk, Nasser M

“…Methodology: C57BL/6 mice (n=20) were fed with a high fat diet (60%) for 16 weeks to generate diet induced obese (DIO) mice with body weights between 45–50 gm. …”
Get full text
Get full text

Rapamycin prevented death from renal dysfunction in <i>Tsc2</i>^{Δ<i>podocyte</i>}. by Wakiko Iwata (8600457)

“…<p>(<b>A</b>) <i>Tsc2</i>^{Δ<i>podocyte</i>} mice treated with rapamycin had improved survival compared to vehicle-treated <i>Tsc2</i>^{Δ<i>podocyte</i>} mice. …”

Abnormal preoperative haematological parameters in Endometrial cancer; reflecting tumour aggressiveness or reduced response to radiotherapy? by Stephanie W. Vrede (17751147)

“…In the entire cohort, anaemia remained independently associated with decreased disease-specific survival (HR 2.31, 95% CI (1.19–4.50), <i>P</i> = 0.013) after adjusting for age, the abnormal haematological parameters and ESGO/ESTRO/ESP risk groups. …”

Comparative interaction study of elisidepsin and the plasma membrane of HCT-116 and HCT-116-Irv cells. by José Manuel Molina-Guijarro (814644)

“…Pink mask and pink cursor correspond to elisidepsin complexes, containing elisidepsin, Irv-OG488 and Irv-A555 molecules at distances shorter than 50 Å, mainly located in the plasma membrane of affected cells. …”

De-repression of endogenous retroelements triggers viral mimicry, interferon, and cytokine response. by Sarfraz Shafiq (13259589)

“…<p><b>(A)</b> Volcano plot of ATAC-seq results for sequence repeats with increased (blue) and decreased (red) chromatin accessibility in ATRX-null microglia. …”

Transition Metal Substitution Effects on Metal-to-Polyoxometalate Charge Transfer by Elliot N. Glass (1648816)

“…A series of hetero-bimetallic transition metal-substituted polyoxometalates (TMSPs) were synthesized based on the Co^II-centered ligand [Co^IIW₁₁O₃₉]^10–. …”

Information S1 - Hypoxia Increases Gefitinib-Resistant Lung Cancer Stem Cells through the Activation of Insulin-Like Growth Factor 1 Receptor by Akiko Murakami (515972)

“…Treatment with YC-1 significantly decreased the number of HIF1α-positive cells in a dose-dependent manner. …”

Knock out VGLL4 in valvar endothelial cells leads to hypertrophy and compromised heart function on later stage. by Wei Yu (43094)

“…<p>(A) Gross front view of hearts from 9-month-old <i>Tie2</i>^<i>Cre+</i><i>;Vgll4</i>^<i>fl/-</i> and <i>Vgll4</i>^<i>fl/-</i> control hearts. …”

Larvicidal and macrofilaricidal efficacy of Closantel and Morantel against mosquito larvae and <i>Setaria digitata</i> nematodes by Megan Hall (506400)

“…While malaria incidence in India has decreased by nearly 50% in recent years, India holds 66% of the WHO SEA region’s malaria burden (World Malaria Report, 2023, Singh et al., 2024). …”

Microsatellite Instability and Mistmatch Repair protein analysis by Salvador J. Diaz-Cano (100072)

“…<p>Microsatellite Instability Testing in CRC and Interpretation</p> <p>Microsatellite instability is a type of mutation that occurs in microsatellite regions (short polymorphic DNA segments) by nucleotide addition (increased size) or nucleotide loss (decreased size) in the repeats. …”

Molecular and Peritoneal Microvascular Changes Cause Peritoneal Membrane Dysfunction by Uremia-Related Mechanisms by Zakaria, El-Rasheid

Get full text
Get full text

The tombusvirus p33 replication protein binds to the yeast Scs2p VAP protein in the ER. by Daniel Barajas (255452)

“…<p>(A) The split ubiquitin assay was used to test binding between p33 and Scs2p in wt (NMY51) yeast. …”

Reduced control model M4: Normative evidence accumulation. by Veith Weilnhammer (2909060)

“…History-congruent amounted to 50.73% ± 0.07% of trials (in blue). As in the full model, the no-oscillation model showed a significant bias toward perceptual history T(4.32×10³) = 9.94, <i>p</i> = 4.88×10⁻²³; upper panel). …”

SAP regulates the stability of KIX8 and KIX9. by Na Li (6550)

“…<p><b>(A-B)</b> The proteasome inhibitor MG132 stabilizes KIX8 (<b>A</b>) and KIX9 (<b>B</b>). …”

Removing an Ectopic Cystic Parathyroid Adenoma in the Anterior Mediastinum via Robotic-Assisted Thoracoscopic Surgery by Michael Tyler Guinn (14783498)

“…<p>This video demonstrates a case of a seventy-four-year-old woman found to have persistent primary hyperparathyroidism after bilateral neck exploration, implicating an anterior mediastinal cyst as an ectopic parathyroid adenoma. …”

High-Spin Molecules:  Hexanuclear Mn^III Clusters with [Mn₆O₄X₄]⁶⁺ (X = Cl^-, Br^-) Face-Capped Octahedral... by Guillem Aromí (2440510)

“…These values indicate a <i>S</i> = 12 ground state. Fitting of magnetization vs field data collected in the 2.00−15.0 K and 0.500−50.0 kG ranges confirmed <i>S</i> = 12 ground states with <i>D</i> ≈ 0 cm^-1.…”

Regulatory interactions between <i>Hoxb1</i>, <i>Hoxb2</i>, and <i>Hoxa2</i> in r4. by Maria Di Bonito (280277)

“…<p>(A) The diagrams above the panels indicate the interactions between <i>Hoxb1</i> and <i>Hoxb2</i>. …”

<i>topbp1</i>^{<i>cas003</i>} mutants manifest deficient DNA damage repair capability. by Lei Gao (6566)

“…<p>(A-H’) Immuno-staining of γH2AX (green), <i>c-myb</i> fluorescent <i>in situ</i> hybridization (red) and DAPI stain (blue) in sibling and <i>topbp1</i>^{<b><i>cas003</i></b>} mutant embryos at 3.5dpf. …”

Reduced control model M2: Only oscillation of the likelihood. by Veith Weilnhammer (2909060)

“…History-congruent amounted to 50.76% ± 0.07% of trials (in blue). As in the full model, the likelihood-oscillation-only model showed a significant bias toward perceptual history T(4.32×10³) = 10.29, <i>p</i> = 1.54×10⁻²⁴; upper panel). …”

Screening of Qatari Microalgae and Cyanobacteria for Application in CO2 Utilization by Schipper, Kira

Get full text
Get full text