Video_1_Pro-Inflammatory Implications of 2-Hydroxypropyl-β-cyclodextrin Treatment.mov by Tom Houben (3185082)

“…The inflammatory and cholesterol-depleting effects of CD were first investigated in low-density lipoprotein receptor knockout (Ldlr^-/) mice that were transplanted with Npc1^nih or Npc1^wt bone marrow and were fed either regular chow or a high-fat, high-cholesterol (HFC) diet for 12 weeks, thereby creating an extreme model of lysosomal cholesterol-induced metabolic inflammation. …”

Table_1_Condensed Tannins in White Clover (Trifolium repens) Foliar Tissues Expressing the Transcription Factor TaMYB14-1 Bind to Forage Protein and Reduce Ammonia and Methane Emis... by Marissa B. Roldan (7023566)

“…However, the transformation of white clover with the TaMYB14-1 transcription factor from Trifolium arvense has resulted in the production of CTs in leaves up to 1.2% of dry matter (DM). In this study, two generations of breeding elevated foliar CTs to >2% of DM. …”

Image_4_Effects of Allicin on Late Sodium Current Caused by ΔKPQ-SCN5A Mutation in HEK293 Cells.TIF by Yating Chen (6707360)

“…Application of Allicin 30 μM reduced the late sodium current (I_Na,L) of the Nav1.5 channel current encoded by ΔKPQ-SCN5A from 1.92 ± 0.12 to 0.65 ± 0.03 pA/pF (P < 0.01, n = 15), which resulted in the decrease of I_Na,L/I_Na,P (from 0.94% ± 0.04% to 0.32% ± 0.02%). …”

Video_5_Pro-Inflammatory Implications of 2-Hydroxypropyl-β-cyclodextrin Treatment.mov by Tom Houben (3185082)

“…The inflammatory and cholesterol-depleting effects of CD were first investigated in low-density lipoprotein receptor knockout (Ldlr^-/) mice that were transplanted with Npc1^nih or Npc1^wt bone marrow and were fed either regular chow or a high-fat, high-cholesterol (HFC) diet for 12 weeks, thereby creating an extreme model of lysosomal cholesterol-induced metabolic inflammation. …”

Video_4_Pro-Inflammatory Implications of 2-Hydroxypropyl-β-cyclodextrin Treatment.mov by Tom Houben (3185082)

“…The inflammatory and cholesterol-depleting effects of CD were first investigated in low-density lipoprotein receptor knockout (Ldlr^-/) mice that were transplanted with Npc1^nih or Npc1^wt bone marrow and were fed either regular chow or a high-fat, high-cholesterol (HFC) diet for 12 weeks, thereby creating an extreme model of lysosomal cholesterol-induced metabolic inflammation. …”

Table_5_Pro-Inflammatory Implications of 2-Hydroxypropyl-β-cyclodextrin Treatment.docx by Tom Houben (3185082)

“…The inflammatory and cholesterol-depleting effects of CD were first investigated in low-density lipoprotein receptor knockout (Ldlr^-/) mice that were transplanted with Npc1^nih or Npc1^wt bone marrow and were fed either regular chow or a high-fat, high-cholesterol (HFC) diet for 12 weeks, thereby creating an extreme model of lysosomal cholesterol-induced metabolic inflammation. …”

The importance of the adaptive threshold. by Jorge F. Mejias (228294)

Fig 4 - by Samuel Thomas (6001970)

“…Volcano plots show 3079 and 2658 total <i>m/z</i> features, respectively; enlarged dots indicate significantly modulated features (Student’s <i>t</i>-test <i>p</i>-value < 0.05 and fold-change ≥ 50%); red indicates increase with JC virus, green indicates decrease with JC virus. …”

siRNAs targeting IDH1. by Xi Chen (35903)

“…Two good siRNAs (-G-) and three bad siRNAs (-B-) are designed to target the IDH1 gene; all of them decrease the target gene expression by about 50%. (B–E) The relative expression levels of off-target genes predicted by Picky. …”

SIRT1 regulates the maintenance of the dendritic tree. by Juan F. Codocedo (304388)

“…Neurons were fixed at 14 DIV and immunostained against Tau protein. (<b>A</b>) Representative images of Tau immunodetection in trasfected GFP positive neurons. …”

Laccase-catalyzed iodination of different mono-methoxy-substituted phenolic compounds (structures: see Figure 2). by Julian Ihssen (417694)

“…a<p>Reaction conditions: 4 mM educt, 50 mM potassium iodide, 100 µM ABTS and 0.25 mg mL⁻¹<i>T. versicolor</i> laccase, % conversion was calculated as the relative decrease in educt peak area compared to enzyme-free control reactions.…”

Assessment of vascular density with CD31 labeling. by Deepa Sharma (278210)

“…Scale bar: 50 μm. (B) Quantification of vascularity from whole tumour sections measured from high magnification microscopy indicates a decrease in vascularity with combined treatment (570 kPa, 40 min) when compared with heat alone 0 kPa, 40 min (n = 3–5). …”

Effect of miR155 on the expression of target genes. by Cui Lei (110562)

“…Treating miR155-overexpressing cells with EGF resulted in a further decrease of SMAD2. No significant changes in TCF4 or CMYC mRNA were observed between EGF-treated and miR155 mimic-transfected cells. …”

Normal occlusion in maturational life process by Daniela GARIB (12682165)

“…Objective: In this article, the occlusal and facial aging changes occurred during almost 50 years of follow-up are described. A normal occlusion sample from Bauru Dental School, University of São Paulo, Brazil, was evaluated at 13 (T1), 17 (T2) and 60 (T3) years of age. …”

Medication-overuse headache. Retrospective comparison of preventive treatments by Abouch V. Krymchantowski (5187023)

“…Sudden withdrawal and pharmacological prevention with one or more drugs were carried out. Adherence and the decrease of headache frequency of more than 50% were compared after four months between the one or two, three, and four drug groups. …”

Live-cell imaging of cAMP in Flamindo2/nlsFlamindo2-expressing COS7 cells. by Haruki Odaka (575909)

“…<p>(A) Representative images showing changes in fluorescence intensity (FI) by 50 µM forskolin application in Flamindo2-expressing COS7 cells. …”

Data_Sheet_1_Water in Alkali Aluminosilicate Glasses.DOCX by Robert Balzer (8846273)

“…The density of hydrous glasses linearly decreased with water content above 1 wt%, consistent with the partial molar volume of H₂O of 12 cm³/mol. …”

Loss of the capacity to induce IL-8 in <i>H. pylori</i> recovered from rhesus monkeys is associated with changes in the gene encoding CagY, an essential protein in the T4SS. by Roberto M. Barrozo (383765)

“…<p>(A–E) <i>H. pylori</i> was isolated from five rhesus macaques up to 14 months after experimental infection with <i>H. pylori</i> WT J166. Individual colonies were co-cultured with AGS cells, and ELISA was used to measure IL-8 levels, which were normalized to the WT J166 positive control. …”

Changes of perceived unevenness caused by in-track vibration countermeasures in slab track by Verachtert, R.

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Geographic distribution of random forest model predictions of Spotted and Eastern towhee species identity. by Ximena León Du’Mottuchi (21560805)

“…<b>(B)</b> The same results from <b>(A)</b> are plotted based on the percent of trees in the random forest classifier that supported the correct species identification; when less than 50% of trees supported the correct identification, the classifier made an incorrect species prediction. …”