PLCε lacking the CDC25 domain and lipase activity cannot rescue monolayer integrity and decreased active Rap1 levels. by Peter V. DiStefano (3111639)

SARS-CoV-2 dosing. by Sonia Ndeupen (11993937)

Leaf extracts from <i>L</i>. <i>polystachyus</i> Rehd. decrease blood glucose from tail of experimental T2DM mice after gavage at different weeks. by Jinfei Wang (3366131)

DataSheet1_Nrf2−/− regulated lung DNA demethylation and CYP2E1 DNA methylation under PM2.5 exposure.docx by Mengjie Wu (311329)

“…After exposure to PM_2.5,CYP2E1 mRNA and protein levels were increased in WT mice but decreased in KO mice, and CYP1A1 expression was increased after exposure to PM_2.5 in both WT and KO mice. …”

DataSheet1_Nrf2−/− regulated lung DNA demethylation and CYP2E1 DNA methylation under PM2.5 exposure.docx by Mengjie Wu (311329)

“…After exposure to PM_2.5,CYP2E1 mRNA and protein levels were increased in WT mice but decreased in KO mice, and CYP1A1 expression was increased after exposure to PM_2.5 in both WT and KO mice. …”

Image_2_High Rates of Genome Rearrangements and Pathogenicity of Shigella spp..pdf by Zaira Seferbekova (10583336)

“…We found that Shigella experienced exceptionally high rates of intragenomic rearrangements and had a decreased rate of homologous recombination compared to pathogenic and non-pathogenic E. coli. …”

Correlation in average DNA methylation levels between TMS and EPIC data split by (A) EPIC v2 Type I and (B) Type II probes. by Amy Longtin (21409957)

Subjects:

Supplementary Material for: Toll-like receptor 2 attenuates the formation and progression of Angiotensin II induced abdominal aortic aneurysm in ApoE-/- mice by Zhang Y. (2828780)

“…Methods: Male ApoE-/- and ApoE-/-TLR2-/- mice were treated with AngII. …”

Lung tumor development decreases the proportions of CD103⁺XCR1⁺ DC1s. by Julyanne Brassard (4117441)

BrdU assays demonstrated that depletion of E2F4 ablates the anti-proliferative activity of capsaicin. by Kathleen C. Brown (365508)

“…<p>(A) H69 and DMS114 cells were transfected with the indicated E2F-siRNA as detailed in “<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0010243#s2" target="_blank">Materials and Methods</a>.” …”

LMP1 inhibits the activity of the GCN2 and PERK kinases. by Deo R. Singh (4784112)

Cellular density effect on the cytoskeleton contribution to E-[c(RGDfK)2] and iRGD internalization. by Damien Moncelet (384264)

“…Treatment with colchicine induced a strong decrease of E-[c(RGDfK)2] and iRGD uptakes. For E-[c(RGDfK)2] the uptake results were 46.3%±1.3%, 46.6±3.0, and 47.5%±3.0% at low, medium and high density, respectively. iRGD uptake results were of 55.0%±0.3%, 53.1%±0.1% and 54.8%±0.8% at low, medium and high density, respectively. …”

A Genome-Wide Association Study Uncovers a Genetic Locus Associated with Thoracic-to-Hip Ratio in Koreans by Seongwon Cha (107939)

“…In the initial discovery stage, there was a statistically nominal association between minor alleles of SNP markers on chromosomes 4, 8, 10, and 12, and THR changes (p < 5.0 × 10⁻⁶). …”

Effect of NlNDUFS1 on apoptosis and RRSV infection in <i>N. lugens.</i> by Lianshun Zheng (22086585)

Coefficient of variation (CV) decrease for estimating the true concentration in dependence of probe replication. by Alex E. Pozhitkov (62910)

Downstream molecular effects of knockdown or overexpression of eEF-2K in MDA-MB-231 cells. by Ibrahim Tekedereli (149655)

“…(<b>A–B</b>) Knockdown of eEF-2K by siRNA increases expression levels of p27^Kip1 (A), while decreasing cyclin D1 (A) and c-Myc (B) levels. …”

Histone acetylation and E2F1 binding at the <i>BRCA1</i> and <i>RAD51</i> promoter regions. by Hideaki Ogiwara (18358)

“…(<b>C–J</b>) Impaired histone acetylation and changes in E2F1 and E2F4 binding at <i>BRCA1</i> and <i>RAD51</i> promoter regions caused by knockdown of CBP and p300. …”

OPG147 has no effect on TBK1 or IRF3-mediated ISRE activation and HT-DNA-induced signaling. by Xue-Mei Yi (18851202)

Impact of Walking on Glycemic Control and Other Cardiovascular Risk Factors in Type 2 Diabetes: A Meta-Analysis by Shanhu Qiu (646356)

“…Walking significantly decreased glycosylated haemoglobin A1c (HbA1c) by 0.50% (95% confidence intervals [CI]: −0.78% to −0.21%). …”

FOXD3 overexpression suppressed proliferation and enhanced starvation-induced apoptosis in U87MG cells. by Wei Du (88790)