<i>In vivo</i> anti-tumor efficacy of compound 4g (<i>N</i> = 6). by Min Xiao (320004)

BjussuLAAO-II induces cytotoxicity and alters DNA methylation of cell-cycle genes in monocultured/co-cultured HepG2 cells by Ana Rita Thomazela Machado (6047777)

“…BjussuLAAO-II increased the methylation of CCND1 and decreased the methylation of CDKN1A in monoculture and GADD45A in both cell-culture models (p < 0.05). …”

Influence of nuclear proteins on the kinetics of unfolding of the h <i>c-myc</i> GQ structure, assayed by measuring the decrease in FRET activities in the presence of the complemen... by Anna Fekete (144891)

“…</p><p>F-<i>myc</i> GQ-R double labeled FRET oligonucleotide (25 pmol) was incubated either alone or with the tested proteins for one minute in a volume of 50 µl, than its FRET spectra was taken (0 min value). …”

Apoptosis in thymus from cocaine-administered rats. by Kana Unuma (283272)

A PRISMA flowchart illustrated the selection of studies included in our systematic review. by Chenyi Ye (2697208)

A flow chart of cellular phenotype switching at the intracellular scale. by Minna Qiao (836556)

Representative experimental samples. by Weisheng Zhao (3746023)

“…Based on the mechanical test results, reducing humidity can decrease the loss of uniaxial compressive strength (UCS) caused by moisture absorption from approximately 50% to 15.48%. …”

Mechanical testing apparatus and samples. by Weisheng Zhao (3746023)

“…Based on the mechanical test results, reducing humidity can decrease the loss of uniaxial compressive strength (UCS) caused by moisture absorption from approximately 50% to 15.48%. …”

Relationship between UCS, E, and water content. by Weisheng Zhao (3746023)

“…Based on the mechanical test results, reducing humidity can decrease the loss of uniaxial compressive strength (UCS) caused by moisture absorption from approximately 50% to 15.48%. …”

Hygroscopic experimental device. by Weisheng Zhao (3746023)

“…Based on the mechanical test results, reducing humidity can decrease the loss of uniaxial compressive strength (UCS) caused by moisture absorption from approximately 50% to 15.48%. …”

Nucleoid morphology disruption causes aberrant plasmid focus positioning. by Robert Ietswaart (676757)

“…<p>(<b>A</b>) Fluorescence localization of ParB-GFP (green) and Hoechst DNA stain (blue) in <i>mukE</i>, <i>mukF</i>, <i>matP</i> mutants and wild-type cells treated with 50 µg/ml nalidixic acid (Nal). …”

Robustness of results. by Raimundo Atal (18272064)

Thymidine phosphorylase and prostrate cancer cell proliferation inhibitory activities of synthetic 4-hydroxybenzohydrazides: <i>In vitro</i>, kinetic, and <i>in silico</i> studies... by Sumaira Javaid (7886897)

Variations in the prevalence of episiotomy in France between 2010 and 2021 according to the classification for episiotomy practices. by Raphaele Houlbracq (20558509)

Sexual maturity status of female C57BL/6J Mice at different ages. by Yan She (8639796)

Placenta-Enriched LincRNAs <i>MIR503HG</i> and <i>LINC00629</i> Decrease Migration and Invasion Potential of JEG-3 Cell Line by Bruna Rodrigues Muys (2588305)

“…Further analysis, using a cancer cell lines panel, showed that <i>MIR503HG and LINC00629</i> were expressed in 50% and 100% of the cancer cell lines, respectively. …”

HbA1c, BMI and Lipid levels of study participants (n = 382). by Habiba I. Ali (10451382)

PGRP-LC in the gut promotes ageing by <i>A</i>. <i>persici</i>. by Taro Onuma (15195377)

Addressing a Trapped High-Energy Water: Design and Synthesis of Highly Potent Pyrimidoindole-Based Glycogen Synthase Kinase-3β Inhibitors by Stanislav Andreev (11067165)

“…Surprisingly, our results demonstrate that this high-energy water was not displaced by our potent inhibitor (<i>S</i>)-3-(3-((7-ethynyl-9<i>H</i>-pyrimido­[4,5-<i>b</i>]­indol-4-yl)­(methyl)­amino)­piperidin-1-yl)­propanenitrile (<b>(<i>S</i>)</b>-<b>15</b>, IC₅₀ value of 6 nM). Instead, only a subtle shift in the location of this water molecule resulted in a dramatic decrease in the energy of this high-energy hydration site, as shown by the WaterMap analysis combined with microsecond timescale molecular dynamics simulations. …”

Addressing a Trapped High-Energy Water: Design and Synthesis of Highly Potent Pyrimidoindole-Based Glycogen Synthase Kinase-3β Inhibitors by Stanislav Andreev (11067165)

“…Surprisingly, our results demonstrate that this high-energy water was not displaced by our potent inhibitor (<i>S</i>)-3-(3-((7-ethynyl-9<i>H</i>-pyrimido­[4,5-<i>b</i>]­indol-4-yl)­(methyl)­amino)­piperidin-1-yl)­propanenitrile (<b>(<i>S</i>)</b>-<b>15</b>, IC₅₀ value of 6 nM). Instead, only a subtle shift in the location of this water molecule resulted in a dramatic decrease in the energy of this high-energy hydration site, as shown by the WaterMap analysis combined with microsecond timescale molecular dynamics simulations. …”