E2F3a/E2F5/p130 triple transgenic lens histology and BrdU incorporation assays by Qin Chen (44010)

“…The number of BrdU positive fiber cells (arrow head) in the triple transgenic lens () decreased by about 50% when compared to the E2F3a single transgenic lens (). …”

LeuB directly regulates amino acid biosynthesis, nitrogen metabolism and iron metabolism. by Nanbiao Long (5900231)

“…(D) Northern blot analyses demonstrating that during iron starvation, lack of LeuB results in downregulation of genes involved in BCAA biosynthesis, nitrogen metabolism and iron homeostasis. (E) Compared to WT, lack of LeuB results in decreased production of TAFC. …”

Facility-Based Delivery during the Ebola Virus Disease Epidemic in Rural Liberia: Analysis from a Cross-Sectional, Population-Based Household Survey by John Ly (2901986)

“…</p><p>Conclusions</p><p>We detected a 30% decreased odds of FBD after the start of EVD in a rural Liberian county with relatively few cases. …”

Neural network classifiers can distinguish states which differ in either activity or correlations. by Nicholas A. Frost (10739821)

“…In this manner, half the neurons increased their activity in “State B” compared to “State A”; the other half decreased. The proportion of activity transferred was determined by randomly drawing a number with an upper bound ranging from 5% to 50%. …”

Combination therapy of high dose PC1, kansui, and JQ1 reactivates latent HIV in a primary CD4+ T cell model of HIV latency. by Daniele C. Cary (3559394)

“…At 12 days post infection, cells were stimulated for 24 hours with: (A) PC1 (24 μM) and kansui (50 μg/ml) (B) PC1 (24 μM) and JQ1 (0.1 μM) (C) e PC1 (24 μM), kansui (50 μg/ml), and JQ1 (0.1 μM). …”

Combination therapy of low dose PC1, kansui, and JQ1 reactivates latent HIV in a primary CD4+ T cell model of HIV latency. by Daniele C. Cary (3559394)

“…At 12 days post infection, cells were stimulated for 24 hours with: (A) single and double PC1 (6 μM) and kansui (50 μg/ml) (B) single and double PC1 (6 μM) and JQ1 (0.1 μM) (C) single and triple PC1 (6 μM), kansui (50 μg/ml), and JQ1 (0.1 μM). …”

Metronidazole-treated <i>Tg(Inta11:NTR)</i> larvae show defects in median fin fold mesenchyme migration, a reduction in median and pectoral fin fold size and a reduction in endoske... by Robert L. Lalonde (4840260)

“…Inta11: NTR + MTZ larvae show a decrease in pectoral fin fold area at 72hpf, and 7dpf, as well as a reduction in endoskeletal disc size at 7dpf (J). …”

Image1_Solifenacin/Mirabegron Induces an Acute Compliance Increase in the Filling Phase of the Capacity-Reduced Urinary Bladder: A Pressure-Volume Analysis in Rats.JPEG by Hsien-Yu Peng (10877709)

“…Though administering to naïve animals solifenacin, but not mirabegron (both 1 × 10⁻⁵−1 × 10⁻¹ mg/kg, i.a.) decreased the peak pressure, both of these reagents exhibited acute increments in the trajectory slope and Cm of the filling phase in a dose-dependent manner (ED₅₀ = 1.4 × 10⁻⁴ and 2.2 × 10⁻⁵ mg/kg, respectively). …”

H3K27me3 spreading is affected in the <i>lhp1</i> and <i>clf</i> mutants. by Alaguraj Veluchamy (3154434)

“…(<b>I)</b> LHP1 binding andH3K27me3 deposition in WT, <i>lhp1</i> and <i>clf</i> across two genes. …”

Contour plots showing how the prevalence of escape amongst A) HLA matched hosts and B) all hosts varies according to the escape and reversion rate. by Helen R. Fryer (194033)

“…The contours show that the prevalence of escape amongst A) HLA-matched hosts and B) all hosts increases as the rate of escape increases and the rate of reversion decreases; however, the increase in escape prevalence in HLA-matched hosts with reversion rate is limited when revision takes an average of 10 years or less. …”

Data Sheet 1_Efficacy and safety of Tongxinluo capsules combined with conventional therapy for acute myocardial infarction: a systematic review and meta-analysis.zip by Dan Ouyang (554436)

“…The meta-analysis revealed that Tongxinluo capsule combined with conventional treatment significantly decreased the 1-month MACCE rate (RR = 0.62, 95% CI 0.47 to 0.81; p = 0.0007), along with the individual risks of 1-month MACCE, including cardiac death (RR = 0.68, 95% CI 0.50 to 0.93; p = 0.02) and myocardial reinfarction (RR = 0.11, 95% CI 0.01 to 0.94; p = 0.04). …”

Data Sheet 2_Efficacy and safety of Tongxinluo capsules combined with conventional therapy for acute myocardial infarction: a systematic review and meta-analysis.zip by Dan Ouyang (554436)

“…The meta-analysis revealed that Tongxinluo capsule combined with conventional treatment significantly decreased the 1-month MACCE rate (RR = 0.62, 95% CI 0.47 to 0.81; p = 0.0007), along with the individual risks of 1-month MACCE, including cardiac death (RR = 0.68, 95% CI 0.50 to 0.93; p = 0.02) and myocardial reinfarction (RR = 0.11, 95% CI 0.01 to 0.94; p = 0.04). …”

Using an ideal observer analysis to investigate the visual perceptual efficiency of individuals with a history of non-suicidal self-injury when identifying emotional expressions by Laura Ziebell (8393820)

“…An increased likelihood of mistaking angry for happy expressions and a decreased likelihood of mistaking sad for surprised expressions were recorded for the HNSSI group compared to controls. …”

Making Acute Tests More Ecologically Relevant: Cadmium Bioaccumulation and Toxicity in an Estuarine Clam under Various Salinities Modeled in a Toxicokinetic–Toxicodynamic Framework... by Qiao-Guo Tan (1422556)

“…The model developed in this study could provide predictions of no-effect concentration (1.7 to 34.9 μg L^–1, end point mortality) and the median lethal concentration (LC₅₀) of Cd at different salinities. In conclusion, we developed a framework for quantifying the multiple effects of salinity and a method for estimating no-effect concentration from acute toxicity tests, which can be used for better assessments of metal risks in estuarine waters.…”

Benzalkonium Chloride Disinfectants Induce Apoptosis, Inhibit Proliferation, and Activate the Integrated Stress Response in a 3‑D <i>in Vitro</i> Model of Neurodevelopment by Josi M. Herron (8068040)

“…By using immunostaining and cell cycle analysis, we found that both BACs induced apoptosis and decreased proliferation of NPCs. To explore the mechanisms underlying their effect on neurosphere growth, we carried out RNA sequencing on neurospheres exposed to each BAC at 50 nM for 24 h, which revealed the activation of the integrated stress response by both BACs. …”

Table_1_Immediate modulatory effects of transcutaneous vagus nerve stimulation on patients with Parkinson’s disease: a crossover self-controlled fMRI study.docx by Chengwei Fu (12129339)

“…Real taVNS was associated with a widespread decrease in ALFF in the right hemisphere, including the superior parietal lobule, precentral gyrus, postcentral gyrus, middle occipital gyrus, and cuneus (voxel p < 0.001, GRF corrected). …”

Supplementary Material for: Practical Value of Anti-Xa Activity in the Evaluation of Extracorporeal Circuit Anticoagulation during Haemodialysis: Results of a Cross-Sectional Singl... by Coene K.L.M. (4545349)

“…<b><i>Conclusion:</i></b> Anti-Xa activity measurements during dialysis can identify patients in whom LMWH dosage should be lowered in a subsequent dialysis session. Whether such an intervention leads to a decrease in haemorrhagic complications needs to be evaluated in prospective studies.…”

Table_1_Multidimensional Mutational Profiling of the Indian HNSCC Sub-Population Provides IRAK1, a Novel Driver Gene and Potential Druggable Target.xlsx by Sagar Sanjiv Desai (11634628)

“…Modelling of the IRAK1 mutation showed a decrease in its binding to known IRAK1 inhibitors.…”

Table_1_Immediate modulatory effects of transcutaneous vagus nerve stimulation on patients with Parkinson’s disease: a crossover self-controlled fMRI study.docx by Chengwei Fu (12129339)

“…Real taVNS was associated with a widespread decrease in ALFF in the right hemisphere, including the superior parietal lobule, precentral gyrus, postcentral gyrus, middle occipital gyrus, and cuneus (voxel p < 0.001, GRF corrected). …”

Table_1_Immediate modulatory effects of transcutaneous vagus nerve stimulation on patients with Parkinson’s disease: a crossover self-controlled fMRI study.docx by Chengwei Fu (12129339)

“…Real taVNS was associated with a widespread decrease in ALFF in the right hemisphere, including the superior parietal lobule, precentral gyrus, postcentral gyrus, middle occipital gyrus, and cuneus (voxel p < 0.001, GRF corrected). …”