Suppression of calpain activity by calpain inhibitors or c siRNA-calpain-II decreased honokiol-induced cell apoptosis. by Meei Ling Sheu (80695)

CPEB3-KO mice with normal mechanical sensation were more sensitive to noxious heat than WT littermate mice. by Sitt Wai Fong (2512264)

“…The total number of cells analyzed from 3 animals are shown in parentheses. Scale: 50 μm. (B) CPEB3-KO mice showed high thermal sensitivity as indicated by decreased latency to lift paws in the hot plate test (50°C). …”

Constitutive KIT activation in cells with gain-of function KIT mutations causes increased ROS levels and decreased DJ-1. by Do-Kyun Kim (2176492)

NF-κB inhibition and CD44 down-regulation result in decreased cell proliferation in breast cancer cells. by Shannon M. Smith (115335)

“…<p>Cell proliferation assays were performed using Ki67 staining. MDA-MB-231 (<b>A–D</b>) and SUM159 cells (<b>E–H</b>) were treated with either a DMSO control or Bay-11-7082 at different concentrations. …”

Simulation results predict the role of AC in driving the in-phase behavior and decreasing time delay for inversely out-of-phase behavior. by Lingxia Qiao (19996756)

Cathepsin B and uPAR knockdown decreases Cdk2 activity and the expression of αVβ3 integrin. by Sreelatha Gopinath (238422)

Lifespan of <i>C. elegans</i> is robust to increases or decreases in rDNA copy number within the natural range. by Ashley N. Hall (14755301)

Inhibition of RIP1 or MLKL decreases morbidity and mortality during <i>S</i>. <i>marcescens</i> hemorrhagic pneumonia. by Norberto González-Juarbe (836747)

Blockage of TF expression in PC14PE6/AS2 cells decreased ability of vascular permeability and ascites formation. by Hsuan-Heng Yeh (463876)

Treatment with BMP-7 decreases expression of M1 macrophage marker, iNOS, as well as pro-inflammatory cytokines. by Crystal Rocher (500661)

“…Scale bar  = 50 µm. Histogram <b>B</b> shows quantitative analysis of the percentage of cells expressing iNOS with a significant decrease in the control and ACM+BMP7 and groups and a significant increase in the ACM and ACM+BMP7+Foll groups; n = 5–6. …”

Anti-microbial peptide treatment decreases parasitemia levels in <i>P. yoelii</i> 17XNL infected mice. by Marcela Parra (192362)

Characterization of Niphatenones that Inhibit Androgen Receptor N-Terminal Domain by Carmen A. Banuelos (636867)

“…Both enantiomers had similar IC50 values of 6 µM for inhibiting the full-length AR in a functional transcriptional assay. …”

Panobinostat downregulated Ron mRNA, protein expression and decreased downstream signaling through pAkt, XIAP, and survivin. by Yi Zou (439002)

Down regulation of Nrf2 leads to decreased Mrp1 and sensitized H69AR cells to chemotherapeutic drugs. by Lili Ji (296025)

Auditory fear conditioning induced persistent fear memory and decreased the survival of adult-born cells in both the amygdala and hippocampus. by Lizhu Jiang (522719)

Increased IL-10 production by the lung cells of B cell-deficient μMT mice during chronic infection with <i>M</i>. <i>tuberculosis</i>. by Yong Chen (109188)

PDK1 inhibitor PF-5177624 decreased IGF-I induced AKT and p70S6K phosphorylation. by Sangita M. Baxi (123560)

Geniposide(Gen) significantly decreased the levels of TNF-α and MIP-1α in BALF of bleomycin-induced PF mice. by Jian-Bin Yin (19556105)

IL-10R blockade reverses the inflammation and diminished CD4⁺ T cell response phenotypes observed in the lungs of B cell-depleted C57BL/6 mice during chronic <i>M</i>. <... by Yong Chen (109188)

Data_Sheet_1_Switching to second line MS disease-modifying therapies is associated with decreased relapse rate.PDF by James John Marriott (16935942)