Showing 5,661 - 5,680 results of 39,316 for search '(( 50 ((nn decrease) OR (((mean decrease) OR (a decrease)))) ) OR ( a de decrease ))', query time: 1.04s Refine Results
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    Discovery of a Potent SARM1 Base-Exchange Inhibitor with In Vivo Efficacy by Maude Giroud (2017114)

    Published 2025
    “…When tested in vivo, compound <b>7</b> showed efficacy after oral dosing in a mouse model of peripheral nerve injury by decreasing plasma neurofilament light (NfL) levels at 50 mg/kg compared with vehicle-treated control mice, holding promise for the treatment of neurodegenerative and neurological disorders.…”
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    IL-6-induction of Nox2 and subsequent decrease of parvalbumin and GAD67 expression in PV-positive interneurons is NFκB-dependent. by Laura L. Dugan (264427)

    Published 2009
    “…<sup>#</sup> = significant with respect to IL-6, F<sub>(2,346)</sub> = 12.826, <i>P</i><0.05). (d. e) SN50 also prevented the decrease in expression of parvalbumin and GAD67 induced by IL-6 exposure in PV-interneurons (*F<sub>(2,409)</sub> = 234.7, <i>P</i><0.05; <sup>#</sup>F<sub>(2,409)</sub> = 192.8, <i>P</i><0.05).…”
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