Search alternatives:
nn decrease » _ decrease (Expand Search), gy decreased (Expand Search), b1 decreased (Expand Search)
de decrease » we decrease (Expand Search), _ decrease (Expand Search), teer decrease (Expand Search)
a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
a de » _ de (Expand Search), a d (Expand Search), i de (Expand Search)
nn decrease » _ decrease (Expand Search), gy decreased (Expand Search), b1 decreased (Expand Search)
de decrease » we decrease (Expand Search), _ decrease (Expand Search), teer decrease (Expand Search)
a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
a de » _ de (Expand Search), a d (Expand Search), i de (Expand Search)
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Discovery of a Potent SARM1 Base-Exchange Inhibitor with In Vivo Efficacy
Published 2025“…When tested in vivo, compound <b>7</b> showed efficacy after oral dosing in a mouse model of peripheral nerve injury by decreasing plasma neurofilament light (NfL) levels at 50 mg/kg compared with vehicle-treated control mice, holding promise for the treatment of neurodegenerative and neurological disorders.…”
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IL-6-induction of Nox2 and subsequent decrease of parvalbumin and GAD67 expression in PV-positive interneurons is NFκB-dependent.
Published 2009“…<sup>#</sup> = significant with respect to IL-6, F<sub>(2,346)</sub> = 12.826, <i>P</i><0.05). (d. e) SN50 also prevented the decrease in expression of parvalbumin and GAD67 induced by IL-6 exposure in PV-interneurons (*F<sub>(2,409)</sub> = 234.7, <i>P</i><0.05; <sup>#</sup>F<sub>(2,409)</sub> = 192.8, <i>P</i><0.05).…”
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