Supplementary Material for: Impact of Early-Onset or Worsening Anemia in Patients With Myelofibrosis Treated With Ruxolitinib: A Post Hoc Analysis of the JUMP Study by figshare admin karger (2628495)

NaCu₆Se₄: A Layered Compound with Mixed Valency and Metallic Properties by Mihai Sturza (1543963)

2D gel of cell wall/membrane proteins from <i>E. coli</i> and <i>B. subtilis</i> after CHX treatment. by Hon-Yeung Cheung (165004)

“…<p>Proteins extracted from the cell wall fraction of (A) <i>E. coli</i> and (B) <i>B. subtilis</i> were separated by isoelectric focusing (pH 3–10) and subsequent 12% SDS polyacrylamide gel followed by Coomassie Blue staining. …”

The ratio of APP localized in lipid rafts was higher in the CHO PS1 ΔE9 cells than in the CHO PS1 WT cells. by Yoon Young Cho (838272)

“…The gradients were harvested from top to bottom to obtain 12 fractions, and equal volumes of each fraction were loaded on SDS gels. (<b>a</b>) A representative western blot shows the APP and caveolin (lipid raft marker) expression levels in the CHO PS1 WT and ΔE9 cells. …”

Table_1_The E3 Ubiquitin Ligase NEDD4L Targets OGG1 for Ubiquitylation and Modulates the Cellular DNA Damage Response.DOCX by Jonathan R. Hughes (9632093)

“…Furthermore, ubiquitylation of OGG1 by NEDD4L in vitro inhibits its DNA glycosylase/lyase activity. As a consequence of prolonged OGG1 stability and increased excision activity in the absence of NEDD4L, cells display increased DNA repair capacity but conversely that this decreases cell survival post-irradiation. …”

Table_1_Caspase-8 Inhibition Prevents the Cleavage and Degradation of E3 Ligase Substrate Receptor Cereblon and Potentiates Its Biological Function.doc by Liang Zhou (85586)

“…<p>Cereblon (CRBN), a substrate receptor of cullin 4-RING E3 ligase (CRL4), mediates the ubiquitination and degradation of constitutive substrates and immunomodulatory drug-induced neo-substrates including MEIS2, c-Jun, CLC1, IKZF1/3, CK1α, and SALL4. …”

Pathogenic implications for autoimmune mechanisms derived by comparative eQTL analysis of CD4⁺ versus CD8⁺ T cells by Silva Kasela (817613)

“…Most remarkably, we identify a common missense variant in <i>IL27</i>, associated with type 1 diabetes that results in decreased functional activity of the protein and reduced expression levels of downstream <i>IRF1</i> and <i>STAT1</i> in CD4⁺ T cells only. …”

Presentation_1_Inhibition of Lung Tumor Development in ApoE Knockout Mice via Enhancement of TREM-1 Dependent NK Cell Cytotoxicity.pdf by Yong Sun Lee (6852212)

“…Knockdown of ApoE expression in lung cancer cells and B16F10 cells also decreased cancer cell growth and metastasis. …”

Presentation_1_Inhibition of Lung Tumor Development in ApoE Knockout Mice via Enhancement of TREM-1 Dependent NK Cell Cytotoxicity.pdf by Yong Sun Lee (6852212)

“…Knockdown of ApoE expression in lung cancer cells and B16F10 cells also decreased cancer cell growth and metastasis. …”

Cooperation of maternal and zygotic Dvl2 and Dvl3a in AP patterning. by Yan-Yi Xing (5597996)

“…(E, E’) Strongly reduced <i>sp5l</i> expression in MZ<i>dvl2</i>;MZ<i>dvl3a</i> mutants. …”

DataSheet_1_First description of in situ chlorophyll fluorescence signal within East Antarctic coastal polynyas during fall and winter.docx by Lucie Bourreau (16698258)

“…An additional signal occurring at 130m depth in August within CDP may result from in situ growth of phytoplankton due to potential adaptation to low irradiance or remnant chlorophyll-a that was advected into the polynya. The decrease and deepening of the fluorescence signal from February to August was accompanied by the deepening of the mixed layer depth and a cooling and salinification of the water column in both polynyas. …”

DataSheet_1_First description of in situ chlorophyll fluorescence signal within East Antarctic coastal polynyas during fall and winter.docx by Lucie Bourreau (16698258)

“…An additional signal occurring at 130m depth in August within CDP may result from in situ growth of phytoplankton due to potential adaptation to low irradiance or remnant chlorophyll-a that was advected into the polynya. The decrease and deepening of the fluorescence signal from February to August was accompanied by the deepening of the mixed layer depth and a cooling and salinification of the water column in both polynyas. …”

Fig 1 - by Jevgeni Tarassov (13889285)

Cysteine protease inhibitor E₆₄ increased the clearance of the bacteria on the ocular surface in infected WT mouse but not in SP-D KO mice. by Zhiyong Zhang (44058)

“…<i>aureus</i> (10⁷ CFUs/eye) in infected WT and SP-D KO mice in the presence or absence of 10 nM of cysteine protease inhibitor (E₆₄). The CFUs of bacteria were significantly decreased (p<0.05) in the tear fluid of the infected WT mice in the presence of E₆₄ compared to its absence at both 3 and 6 h after infection. …”

Image_2_Rbfox1 Is Expressed in the Mouse Brain in the Form of Multiple Transcript Variants and Contains Functional E Boxes in Its Alternative Promoters.jpg by Sonia Casanovas (8799128)

“…<p>The RNA-binding protein RBFOX1 is an important regulator of neuron development and neuronal excitability. Rbfox1 is a dosage-sensitive gene and in both mice and humans, decreased expression of Rbfox1 has been linked to neurodevelopmental disorders. …”

Tuberous Sclerosis Complex 1 Regulates dE2F1 Expression during Development and Cooperates with RBF1 to Control Proliferation and Survival by Ting-Chiu Hsieh (243481)

“…<div><p>Previous studies in <em>Drosophila melanogaster</em> have demonstrated that many tumor suppressor pathways impinge on Rb/E2F to regulate proliferation and survival. Here, we report that Tuberous Sclerosis Complex 1 (TSC1), a well-established tumor suppressor that regulates cell size, is an important regulator of dE2F1 during development. …”

Image_4_Rbfox1 Is Expressed in the Mouse Brain in the Form of Multiple Transcript Variants and Contains Functional E Boxes in Its Alternative Promoters.jpg by Sonia Casanovas (8799128)

“…<p>The RNA-binding protein RBFOX1 is an important regulator of neuron development and neuronal excitability. Rbfox1 is a dosage-sensitive gene and in both mice and humans, decreased expression of Rbfox1 has been linked to neurodevelopmental disorders. …”

Image_3_Rbfox1 Is Expressed in the Mouse Brain in the Form of Multiple Transcript Variants and Contains Functional E Boxes in Its Alternative Promoters.jpg by Sonia Casanovas (8799128)

“…<p>The RNA-binding protein RBFOX1 is an important regulator of neuron development and neuronal excitability. Rbfox1 is a dosage-sensitive gene and in both mice and humans, decreased expression of Rbfox1 has been linked to neurodevelopmental disorders. …”

Image_1_Rbfox1 Is Expressed in the Mouse Brain in the Form of Multiple Transcript Variants and Contains Functional E Boxes in Its Alternative Promoters.jpg by Sonia Casanovas (8799128)

“…<p>The RNA-binding protein RBFOX1 is an important regulator of neuron development and neuronal excitability. Rbfox1 is a dosage-sensitive gene and in both mice and humans, decreased expression of Rbfox1 has been linked to neurodevelopmental disorders. …”

Table_1_Rbfox1 Is Expressed in the Mouse Brain in the Form of Multiple Transcript Variants and Contains Functional E Boxes in Its Alternative Promoters.pdf by Sonia Casanovas (8799128)

“…<p>The RNA-binding protein RBFOX1 is an important regulator of neuron development and neuronal excitability. Rbfox1 is a dosage-sensitive gene and in both mice and humans, decreased expression of Rbfox1 has been linked to neurodevelopmental disorders. …”