Metabolic factors, lifestyle habits, and possible polyneuropathy in early type 2 diabetes: A nationwide study of 5,249 patients in the Danish DD2 cohort by Diana H. Christensen (8599231)

“…Smoking: aPR 1.50 (1.24; 1.81) and lack of physical activity (0 vs ≥3 days/week): aPR 1.61 (1.39; 1.85) were also associated with DPN. …”

Table 1_Bone mineral density and sex hormone binding globulin as potential mediators of the causal effect of urolithiasis on osteoporosis risk: a Mendelian randomization.xlsx by Jiawei Guo (1488853)

“…Previous observational studies have found a relationship between these two diseases that increases the risk of each other, but whether there is a direct causal link is still unclear. …”

MYK-461 reduces contractility in feline HCM in an exposure-dependent manner. by Joshua A. Stern (819269)

DataSheet_1_Biomarkers predicting clinical outcomes in nasopharyngeal cancer patients receiving immune checkpoint inhibitors: A systematic review and meta-analysis.docx by Xiaoyan Qian (1572298)

“…Patients with lower plasma EBV DNA level at baseline obtained a significant benefit on PFS than those with higher plasma EBV DNA level (HR = 0.52, 95% CI: 0.42-0.63, P < 0.001). …”

DataSheet_2_Biomarkers predicting clinical outcomes in nasopharyngeal cancer patients receiving immune checkpoint inhibitors: A systematic review and meta-analysis.pdf by Xiaoyan Qian (1572298)

“…Patients with lower plasma EBV DNA level at baseline obtained a significant benefit on PFS than those with higher plasma EBV DNA level (HR = 0.52, 95% CI: 0.42-0.63, P < 0.001). …”

Table 1_Evaluating biomass and carbon stock responses to thinning and pruning in mature Larix principis-rupprechtii Mayr stands: a case study from Northern China.docx by Jamshid Ali (20981393)

Analgesic prescriptions received by patients before commencing the BOA model of care for osteoarthritis: a Swedish national registry study with matched reference and clinical guide... by Allan Abbott (6032138)

“…Since guideline publication, the proportion of the OA cohort having no dispensed prescription analgesics prior to non-pharmacological primary care intervention concordantly increased by 5.0% (95% CI 4.2–5.9). Furthermore, dispensed prescriptions concordantly decreased for non-selective NSAIDs –8.6% (CI –9.6 to –7.6), weak opioids –6.8% (CI –7.7 to –5.9), glucosamine –9.5% (CI –9.8 to –8.8). and hyaluronic acid –1.6% (CI –1.8 to –1.5) but discordantly increased for strong opioids 2.8% (CI 2.1–3.4) and glucocorticoid intra-articular injection for hip OA 2.1% (CI 1.0–3.1).…”

Table_1_Effect of a Low-Carbohydrate Diet With or Without Exercise on Anxiety and Eating Behavior and Associated Changes in Cardiometabolic Health in Overweight Young Women.doc by Mingzhu Hu (12216593)

“…</p>Methods<p>Seventy-four overweight Chinese women [age: 20.8 ± 3.0 years, body mass index (BMI): 25.3 ± 3.3 kg·m⁻²] completed the 4-week randomized controlled trial, which included a LCD group (i.e., ~50 g daily carbohydrate intake) with exercise training 5 days/week (LC-EXE, n = 26), a LCD group without exercise training (LC-CON, n = 25) and a control group that did not modify their habitual diets and physical activity (CON, n = 23). …”

DataSheet_1_Multipotent mesenchymal stromal cells as treatment for poor graft function after allogeneic hematopoietic cell transplantation: A multicenter prospective analysis.pdf by Sophie Servais (534177)

“…A significant decrease in red blood cells and platelets transfusion requirement was observed after MSC (median of 30-days transfusion requirement of 0.5 and 0 from d90-120 post-MSC versus 5 and 6.5 before MSC, respectively, p ≤0.001). …”

Table1_Clinical efficacy and safety of adjunctive treatment of chronic ischemic heart failure with Qishen Yiqi dropping pills: a systematic review and meta-analysis.docx by Wang Xingmeng (17662179)

“…The quality of the literature was assessed according to the Cochrane Reviewers' Handbook 5.0 and the Modified Jadad Scale (with a score of 4–7 rated as high quality). …”

Table 1_Diverging trends in the global burden of ischemic heart disease attributable to non-optimal temperatures: a historical analysis (1990–2021) and 2050 projections.docx by Zehao Jin (11408687)

“…The analysis identified marked sex-specific disparities, characterized by a 41.6% (risk ratio: 1.416, 95% CI not provided) higher mortality risk in males relative to females and a male-to-female DALYs ratio of 1.667. …”

Table_1_Assessing Visceral Obesity and Abdominal Adipose Tissue Distribution in Healthy Populations Based on Computed Tomography: A Large Multicenter Cross-Sectional Study.DOCX by Ming Kong (1836898)

“…Interestingly, SATI was weakly positively correlated with age in women, while SATI was weakly negatively correlated with age in men. In persons with a normal BMI, the proportion of visceral adiposity increases with age, whereas in men with a normal BMI, the proportion of visceral adiposity decreases after the age of 60 years but remains >50%.…”

Image_1_Assessing Visceral Obesity and Abdominal Adipose Tissue Distribution in Healthy Populations Based on Computed Tomography: A Large Multicenter Cross-Sectional Study.TIF by Ming Kong (1836898)

“…Interestingly, SATI was weakly positively correlated with age in women, while SATI was weakly negatively correlated with age in men. In persons with a normal BMI, the proportion of visceral adiposity increases with age, whereas in men with a normal BMI, the proportion of visceral adiposity decreases after the age of 60 years but remains >50%.…”

Data_Sheet_1_State-Dependent Entrainment of Prefrontal Cortex Local Field Potential Activity Following Patterned Stimulation of the Cerebellar Vermis.PDF by Stéfanie A. Tremblay (7554821)

“…Local field potentials were recorded in the right lateral cerebellum (Crus I/II) and bilaterally in the prefrontal cortex (frontal association area, FrA) in adult male Sprague-Dawley rats. Stimulation was delivered to the cerebellar vermis (lobule VII) using single pulses (0.2 Hz for 60 s), or repeated pulses at 1 Hz (30 s), 5 Hz (10 s), 25 Hz (2 s), and 50 Hz (1 s). …”

Replication of YFV-17D cap1 and cap0 in C6/36 cells. by Anja vom Hemdt (19787189)

Ligand Desolvation Steers On-Rate and Impacts Drug Residence Time of Heat Shock Protein 90 (Hsp90) Inhibitors by Doris A. Schuetz (5202461)

“…We discovered that an increased ligand desolvation barrier by introducing polar substituents resulted in a significant <i>k</i>_on decrease. The slowdown was accomplished by introducing polar moieties to those parts of the ligand that point toward a hydrophobic cavity. …”

PI susceptibility and single round infectivity of patient Gag-Protease derived pre-PI therapy and at the time of treatment failure. by Katherine A. Sutherland (797812)

“…<p>Full-length Gag-Protease from pre-PI therapy and failure time-points was amplified or synthesised, and cloned into our Gag-Pol expression vector p8.9NSX+. …”

Image_3_Germinal centers are permissive to subdominant antibody responses.eps by Philippe A. Robert (7350209)

“…Less immunogenic domains reduced the dominance of GC responses to more immunogenic domains, albeit at a later time point.</p>Discussion<p>The simulations suggest that increased vaccine valency may decrease immunodominance of the GC response to strongly immunogenic domains and therefore, act as a potential strategy for the natural induction of broadly neutralizing antibodies in GC reactions.…”

Image_1_Germinal centers are permissive to subdominant antibody responses.eps by Philippe A. Robert (7350209)

“…Less immunogenic domains reduced the dominance of GC responses to more immunogenic domains, albeit at a later time point.</p>Discussion<p>The simulations suggest that increased vaccine valency may decrease immunodominance of the GC response to strongly immunogenic domains and therefore, act as a potential strategy for the natural induction of broadly neutralizing antibodies in GC reactions.…”

Image_2_Germinal centers are permissive to subdominant antibody responses.eps by Philippe A. Robert (7350209)

“…Less immunogenic domains reduced the dominance of GC responses to more immunogenic domains, albeit at a later time point.</p>Discussion<p>The simulations suggest that increased vaccine valency may decrease immunodominance of the GC response to strongly immunogenic domains and therefore, act as a potential strategy for the natural induction of broadly neutralizing antibodies in GC reactions.…”