Supplementary Material for: The Protective Effects of Κ-Opioid Receptor Stimulation in Hypoxic Pulmonary Hypertension Involve Inhibition of Autophagy Through the AMPK-MTOR Pathway by Zhou Y. (3218202)

“…<b><i>Results:</i></b> Inhibition of autophagy by the administration of chloroquine prevented the development of HPH in the rat model, as evidenced by significantly reduced mPAP and RVP, as well as decreased autophagy. U50,488H mimicked the effects of chloroquine, and the effects of U50,488H were blocked by nor-BNI, a selective κ-opioid receptor antagonist. …”

BTK Expression Levels Control DNA Binding Activity and Transcription Factor Function of Ikaros. by Hong Ma (48973)

“…Each siRNA was used at a 50 nM concentration. BTK siRNA (but not Ku80 siRNA) resulted in depletion of BTK protein without a decrease in the amount of IK protein. …”

Estimation accuracy in the psychological sciences - Fig 4 by Clintin P. Davis-Stober (2881802)

“…Minimum sample size (per condition) for a power of 50% at the 5% level. The needed sample size per condition decreases with the number of conditions. …”

PCB19 blunts thapsigargin-induced increases in sustained [Ca²⁺]_i levels. by Se-Young Choi (175210)

“…<p><b>A</b>, Fura-2-loaded PC12 cells were treated with 1 μM thapsigargin; 5 minutes later (at the sustained phase), cells were challenged with 50 μM of either PCB4, PCB19, or PCB100. …”

Bariatric surgery and the coronary artery calcium score. by Daniel da Costa Lins (6879683)

“…Results: the FRS decreased 50% between the pre and postoperative evaluations. …”

Collateral effects are pervasive and vary across parallel evolution experiments in <i>E</i>. <i>faecalis</i>. by Jeff Maltas (1598305)

“…Although the color scale ranges from a 4× decrease to a 4× increase in IC₅₀, it should be noted that both resistance to the selecting drug (diagonal blocks) and collateral effects can be significantly higher. …”

The airway intrinsic BX-C code determines the outcome of <i>hh</i> signaling. by Ryo Matsuda (685668)

“…Note that Salm expression in DT shows a posterior-to-anterior decrease. Upon overexpression of <i>Ubx</i> (G), <i>abdA</i> (H) or <i>AbdB</i> (I), DTa1 becomes negative for Kni and positive for Salm (asterisks). …”

Injection of dGAG-DFX-101 Releases Sequestered P. falciparum IE into Circulation in M. fascicularis by Anna M Vogt (21629)

“…In contrast, the amount of material in the heart of the monkey left untreated decreased by 22% (ID 5018). The analysis of the radioactivity in the hearts was performed by comparing amounts of material present at time point 30 min and at time point 60 min, after the dGAG-DFX-101 was injected. …”

ETCO₂ in an animal undergoing two-lung, left-lung, and right-lung ventilations via a standard endotracheal tube during cardiopulmonary resuscitation. by Dong Hyun Ryu (5095394)

“…Immediately after the endotracheal tube was advanced into the right main bronchus (point E), ETCO₂ decreased to 12.5 mmHg and remained between 10.0 and 11.0 mmHg after stabilization.…”

Data_Sheet_4_Omeprazole Increases the Efficacy of Acyclovir Against Herpes Simplex Virus Type 1 and 2.PDF by Martin Michaelis (23843)

“…Omeprazole 80 μg/mL caused a 10.8-fold (Vero cells) and 47.7-fold (HaCaT cells) decrease of the acyclovir concentrations that reduced HSV-1-induced CPE formation by 50% (IC₅₀). …”

Data_Sheet_1_Unequal Impact of COVID-19 on Private and Academic Neurosurgical Workforce: Results of an International Survey.PDF by Sami Ridwan (11510080)

“…</p><p>Conclusion: The lockdown imposed in many countries by the COVID-19 outbreak called for immediate modification of working routine and resulted in a dramatic decrease of elective surgical procedures. …”

Data_Sheet_2_Omeprazole Increases the Efficacy of Acyclovir Against Herpes Simplex Virus Type 1 and 2.PDF by Martin Michaelis (23843)

“…Omeprazole 80 μg/mL caused a 10.8-fold (Vero cells) and 47.7-fold (HaCaT cells) decrease of the acyclovir concentrations that reduced HSV-1-induced CPE formation by 50% (IC₅₀). …”

Data_Sheet_1_Omeprazole Increases the Efficacy of Acyclovir Against Herpes Simplex Virus Type 1 and 2.PDF by Martin Michaelis (23843)

“…Omeprazole 80 μg/mL caused a 10.8-fold (Vero cells) and 47.7-fold (HaCaT cells) decrease of the acyclovir concentrations that reduced HSV-1-induced CPE formation by 50% (IC₅₀). …”

4-Phenyl-1,3-thiazole-2-amines as scaffolds for new antileishmanial agents by Carina Agostinho Rodrigues (5887349)

“…A target fishing study suggested that S-methyl-5-thioadenosine phosphorylase is a potential target to these compounds, which could be explored to enhance activity and decrease the potential toxic side effects. …”

Table_1_In vitro investigation of the antiviral activity of propolis and chitosan nanoparticles against the genotype VII Newcastle disease virus.DOCX by Noura Alkhalefa (13387473)

“…The median tissue culture infectious dose (TCID50) assay demonstrated that the nanoparticles have antiviral effects after NDV exposure resulting in significant decrease in viral titer (TCID50) by 2, 2.66, and 2.5 log10 at 62 μg/ml of chitosan, 13 μg/ml of propolis, and 30 μg/ml of the propolis–chitosan mixture, respectively, compared with the control TCID50 value of 4 log10. …”

Data_Sheet_5_Omeprazole Increases the Efficacy of Acyclovir Against Herpes Simplex Virus Type 1 and 2.PDF by Martin Michaelis (23843)

“…Omeprazole 80 μg/mL caused a 10.8-fold (Vero cells) and 47.7-fold (HaCaT cells) decrease of the acyclovir concentrations that reduced HSV-1-induced CPE formation by 50% (IC₅₀). …”

Table_1_In vitro investigation of the antiviral activity of propolis and chitosan nanoparticles against the genotype VII Newcastle disease virus.DOCX by Noura Alkhalefa (13387473)

“…The median tissue culture infectious dose (TCID50) assay demonstrated that the nanoparticles have antiviral effects after NDV exposure resulting in significant decrease in viral titer (TCID50) by 2, 2.66, and 2.5 log10 at 62 μg/ml of chitosan, 13 μg/ml of propolis, and 30 μg/ml of the propolis–chitosan mixture, respectively, compared with the control TCID50 value of 4 log10. …”

Data_Sheet_3_Omeprazole Increases the Efficacy of Acyclovir Against Herpes Simplex Virus Type 1 and 2.PDF by Martin Michaelis (23843)

“…Omeprazole 80 μg/mL caused a 10.8-fold (Vero cells) and 47.7-fold (HaCaT cells) decrease of the acyclovir concentrations that reduced HSV-1-induced CPE formation by 50% (IC₅₀). …”

Recombination DNA repair was impaired in <i>BRIT1</i>-deficient spermatocytes. by Yulong Liang (241535)

“…Value shown here represents the mean±SD from ∼50 late zygotene spermatocytes for each genotype. …”

Fig 7 - by Abu Baker (12418905)

“…<p><b>A.</b> Images showing a Mitotracker Red CMXROS staining under phase contrast microscope after 24 h treatment of AbSvGNPs, abira, CtGNPs, and SvGNPs at IC-25, IC-50, and IC-75 concentration against DU145 cell lines. …”