Image_8_Consecutive Hypoxia Decreases Expression of NOTCH3, HEY1, CC10, and FOXJ1 via NKX2-1 Downregulation and Intermittent Hypoxia-Reoxygenation Increases Expression of BMP4, NOT... by Yung-Yu Yang (9343376)

“…Inhibition of HIF1A or NKX2-1 expression by siRNA transfection respectively decreased BMP4/NOTCH1/MKI67/OCT4/MUC5AC and NOTCH3/HEY1/CC10/FOXJ1 expression in the HBE cells cultured under intermittent H/R to the same levels under normoxia. …”

Image_7_Consecutive Hypoxia Decreases Expression of NOTCH3, HEY1, CC10, and FOXJ1 via NKX2-1 Downregulation and Intermittent Hypoxia-Reoxygenation Increases Expression of BMP4, NOT... by Yung-Yu Yang (9343376)

“…Inhibition of HIF1A or NKX2-1 expression by siRNA transfection respectively decreased BMP4/NOTCH1/MKI67/OCT4/MUC5AC and NOTCH3/HEY1/CC10/FOXJ1 expression in the HBE cells cultured under intermittent H/R to the same levels under normoxia. …”

Treatment with mitochondrial shuttle inhibitors, GKA50, Ranolazine and glucose results in significant decreases in superoxide concentration as detected by coelenterazine chemilumin... by Laura L. Bronsart (844933)

SIRT1 is involved in the attenuation of H₂O₂-induced senescence by resveratrol. by Yasuo Ido (172159)

AMPK activation increases FOXO3 protein expression. by Yasuo Ido (172159)

Correlation between hub genes and 50 hallmark signaling pathways. by Jiyong Zhang (2498740)

Regions (α-helices, β-sheets, and loops) showing an average increase or decrease of RMSF in the MTs compared to the WT; RMSF of a particular structure is taken to be increased or decreased if there is an average change in RMSF of >0.03 nm in at least ≥50% of its residues. by Kumaraswamy Naidu Chitrala (612025)

“…<p>Regions (α-helices, β-sheets, and loops) showing an average increase or decrease of RMSF in the MTs compared to the WT; RMSF of a particular structure is taken to be increased or decreased if there is an average change in RMSF of >0.03 nm in at least ≥50% of its residues.…”

Resveratrol Prevents Oxidative Stress-Induced Senescence and Proliferative Dysfunction by Activating the AMPK-FOXO3 Cascade in Cultured Primary Human Keratinocytes by Yasuo Ido (172159)

“…In addition, we found that treatment of keratinocytes with Ex527, a specific inhibitor of sirtuin 1 (SIRT1), attenuated the ability of resveratrol to suppress senescence. …”

DMB treatment improved neurological deficit and decreased infarct volume 24 h after MCAO. by Huinan Zhang (849524)

The material parameters of the 50 MPa concrete for the simulations [26]. by Xiaochao Jin (3993236)

Fli-1 directly activates miR-17-92 promoter and contributes to miR-17 and miR-20a expression in NN10#5 cells. by Samer Kayali (133888)

3D snapshots of the tumor system with single-agent BHQ880 treatment at (a) time step 40, (b) time step 50 and (c) time step 120. by Minna Qiao (836556)

S1 Dataset - by Nelmo Jordão Manjate (16324619)

“…This study aimed to estimate the cost of SARS-CoV-2 diagnosis of symptomatic suspected patients by reverse transcription polymerase chain reaction (RT-PCR) and antigen rapid diagnostic tests (Ag-RDT) in Mozambique. We conducted a retrospective cost analysis from the provider’s perspective using a bottom-up, micro-costing approach, and compared the direct costs of two nasopharyngeal Ag-RDTs (Panbio and Standard Q) against the costs of three nasal Ag-RDTs (Panbio, COVIOS and LumiraDx), and RT-PCR. …”

Effect of the Hill coefficient on estimates of <i>ε</i>_max (left column) and IC₅₀ (right column) for the logistic model with drug applied to the growth rate <... by Hope Murphy (8843516)

Conditional depletion of RPS0A significantly decreases translation initiation rates. by Tomáš Kouba (153719)

Minimal dataset. by Jennifer M. Kwan (3350321)

“…However, the cardiovascular risks of dual ICI therapy were offset by its mortality benefit, with dual ICI therapy being associated with a ~25% or 1.3-fold decrease in mortality. Of those with echo prior to ICI initiation, 26% (n = 115/442) had abnormal left ventricular ejection fraction or global longitudinal strain, and of those with echo after ICI initiation, 28% (n = 207/740) had abnormalities. …”

Mutations in <i>DHFR-TS</i> and their role in methotrexate resistance. by Sophia Bigot (16469992)

PTR1 DNA editing and absence of phenotype. by Sophia Bigot (16469992)

The receiver operating characteristic curve (ROC) for using ucfDNA molecules with a size range of 130 to 160 bp within the DHSs to distinguish control subjects with hematuria from... by Meihui Chen (1670020)

Predicted metabolite levels for each reaction intermediate shown in Figure 7 under conditions in which the NAD+:NADH ratio is 31 (Bennett et al. [26]), or decreased by either 0.1-f... by William R. Cannon (608586)