Discovery of a Colon-Targeted Azo Prodrug of Tofacitinib through the Establishment of Colon-Specific Delivery Systems Constructed by 5‑ASA–PABA–MAC and 5‑ASA–PABA–Diamine for the T... by Jiaxing Zhao (3965057)

“…Specifically, compound <b>20g</b> displayed a 3.67-fold decrease of plasma AUC_{(tofacitinib, 0–∞)} and a 9.61-fold increase of colonic AUC_{(tofacitinib, 0–12h)}, compared with tofacitinib at a molar equivalent oral dose. …”

Compound CID 9998128 Is a Potential Multitarget Drug for Alzheimer’s Disease by Nguyen Quoc Thai (5348798)

“…We have probed small molecule compound CID 9998128 as a potential multitarget drug for the Alzheimer’s disease (AD) using <i>in silico</i> and <i>in vitro</i> experiments. …”

Compound CID 9998128 Is a Potential Multitarget Drug for Alzheimer’s Disease by Nguyen Quoc Thai (5348798)

“…We have probed small molecule compound CID 9998128 as a potential multitarget drug for the Alzheimer’s disease (AD) using <i>in silico</i> and <i>in vitro</i> experiments. …”

Resveratrol decreased acetylated RelA/p65. A. by Xiaoxia Zhu (301292)

Linear decrease of delta power (1.1–5.0 Hz) across the first three sleep cycles in the cortical, hippocampal and scalp recordings. by Fabio Moroni (34208)

An Improved Genome Assembly of Azadirachta indica A. Juss. by Binay Panda (768771)

“…The updated genome assembly (v2.0) yielded 3- and 3.5-fold increase in N50 and N75, respectively; 2.6-fold decrease in the total number of scaffolds; 1.25-fold increase in the number of valid transcriptome alignments; 13.4-fold less mis-assembly and 1.85-fold increase in the percentage repeat, over the earlier assembly (v1.0). …”

Incubation of <i>T</i>. <i>brucei</i> with Pol I transcription inhibitors results in a dramatic decrease in VEX1 foci. by Louise E. Kerry (3815164)

S1 Fig - by Asadollahi Parisa (8837432)

Macroscopic and histological assessment of colic tumor and inflammation in mice. by Asadollahi Parisa (8837432)

SCS DKO parasites have decreased mitochondrial ATP content, but are capable of ATP import and ATP hydrolysis. by Gergana Taleva (17131885)

PCA-CGAN K-fold experiment table. by Chao Tang (10925)

PCAECG-GAN K-fold experiment table. by Chao Tang (10925)

Superposition of conserved PARG1 C1-RhoGAP domains bound to RhoA protein. by Zen Kouchi (14898435)

Loss of cytoplasmic incompatibility in <i>Wolbachia</i>-infected <i>Aedes aegypti</i> under field conditions by Perran A. Ross (844275)

“…To investigate the critical temperature range for the loss of <i>Wolbachia</i> infections, we held <i>Ae</i>. <i>aegypti</i> eggs in thermocyclers for one week at a range of cyclical temperatures. …”

Decreased neutrophil and monocyte antigen expression in the paws of anti-S100A9-treated mice. by Annabelle Cesaro (112070)

Synthesis and Characterization of New Organometallic Benzo[<i>b</i>]thiophene Derivatives with Potential Antitumor Properties by André P. Ferreira (2348185)

“…The benzo[<i>b</i>]thiophene derivative raloxifene is a selective estrogen receptor modulator (SERM) that has been found to decrease breast cancer risk in postmenopausal women compared to placebo. …”

Elevated serum IgA, decreased stool IgA, and decreased IgA coating of fecal bacteria in pIgR KO mice. by Kristina J. Betz (5329541)

“…(D) pIgR KO mice showed a 3-fold reduction in the percentage of stool bacteria coated with IgA (<i>P</i><0.0001, Mann-Whitney).…”

Salience of authority-virtue phrases by year. by Daniel Hart (440152)

<i>eIF2A</i> overexpression decreases the cell wall protein levels. by Laura Meyer (4033793)

Sensitivity analysis of 50:50 model. by Rachael Miller Neilan (10678614)

“…<p>A sensitivity analysis was conducted on the 50:50 model with constant 120 pA current to determine the sensitivity of pain output to select model parameters before injury (t = 10), during injury (t = 105), and after injury (t = 240). …”