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GNE-781, A Highly Advanced Potent and Selective Bromodomain Inhibitor of Cyclic Adenosine Monophosphate Response Element Binding Protein, Binding Protein (CBP)
Published 2017“…In pursuit of a more potent and selective CBP inhibitor, we used structure-based design. …”
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Resveratrol decreases PKM2 expression.
Published 2013“…<p>Resveratrol treatment decreases PKM2 mRNA in (A), HeLa; (B), HepG2 and (C), MCF-7; by approximately two-folds. β-actin was taken as endogenous control and normalized to PKM2 mRNA. …”
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Complete data.
Published 2024“…A tenfold decrease or increase in concentration induced only a 2-fold decrease or increase in clot degradation. …”
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Fig 4 -
Published 2024“…A tenfold decrease or increase in concentration induced only a 2-fold decrease or increase in clot degradation. …”
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Aged blood factors decrease cellular responses associated with delayed gingival wound repair
Published 2017“…<div><p>Aging is a gradual biological process characterized by a decrease in cell and organism functions. …”
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Top Genes with Significantly Decreased Transcript Levels at the Site of SSTI<sup>1</sup>.
Published 2015“…<p><sup>1</sup>Top 50 genes with greatest negative change in LFC when comparing infected ears to uninfected ears from challenged mice for each time point represented</p><p><sup>2</sup>Function determined via Entrez (<a href="http://www.ncbi.nlm.nih.gov/" target="_blank">www.ncbi.nlm.nih.gov</a>) or Uniprot (<a href="http://www.uniprot.org/" target="_blank">www.uniprot.org</a>)</p><p><sup>3</sup>LFC = Log Fold Change</p><p>Italicized values indicate transcripts are significantly increased at the indicated time point.…”
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Prolactin receptor immunoreactivity and gene expression is present in corporal skin and decreases during culture.
Published 2013“…(E) PRLR gene expression was detectable in corporal skin from three female subjects (results pooled and expressed as fold change), aged 42–63 years, at day 0 and decreased significantly during serum-free organ culture. …”
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ApoER2 expression increases Aβ production while decreasing Amyloid Precursor Protein (APP) endocytosis: Possible role in the partitioning of APP into lipid rafts and in the regulat...
Published 2011“…<p><b>Copyright information:</b></p><p>Taken from "ApoER2 expression increases Aβ production while decreasing Amyloid Precursor Protein (APP) endocytosis: Possible role in the partitioning of APP into lipid rafts and in the regulation of γ-secretase activity"</p><p>http://www.molecularneurodegeneration.com/content/2/1/14</p><p>Molecular Neurodegeneration 2007;2():14-14.…”
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Image_3_A Shift in Myeloid Cell Phenotype via Down Regulation of Siglec-1 in Island Macrophages of Bone Marrow Is Associated With Decreased Late Erythroblasts Seen in Anemia of Cri...
Published 2019“…There were more (2.5-fold) EEBs and less LEBs (2.4-fold) per million TBM cells in B; with a corresponding decrease in Siglec-1 and Ly6G expressions in EBIMØ associated with EEB. …”
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Image_4_A Shift in Myeloid Cell Phenotype via Down Regulation of Siglec-1 in Island Macrophages of Bone Marrow Is Associated With Decreased Late Erythroblasts Seen in Anemia of Cri...
Published 2019“…There were more (2.5-fold) EEBs and less LEBs (2.4-fold) per million TBM cells in B; with a corresponding decrease in Siglec-1 and Ly6G expressions in EBIMØ associated with EEB. …”