A computational approach for investigating the mutational landscape of RAC-alpha serine/threonine-protein kinase (AKT1) and screening inhibitors against the oncogenic E17K mutation... حسب Thirumal Kumar, D

"…We also performed a virtual screening analysis with 19 AKT inhibitors obtained from the Selleck Chemicals website those satisfied the Lipinski rule of 5. …"
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Structural analysis of missense mutations in galactokinase 1 (GALK1) leading to galactosemia type-2. حسب P, Sneha

"…Molecular docking analysis revealed a decrease in interaction between the protein and ATP in all the 3 mutations, and molecular dynamic simulations of 50 ns showed a loss of stability and compactness in the mutant proteins. …"
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Heme Oxygenase Isoform 1 Regresses Cardiomyocyte Hypertrophy Through Regressing Sodium Proton Exchanger Isoform 1 Activity حسب Sobh, Ahmed

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The Cardiovascular Benefits of Empagliflozin, A Sodium Glucose Cotransporter Inhibitor: Is NHE1 a Viable Target? حسب Al-Shamasi, Al-Anood

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Mycoplasma bovis-induced inhibition of bovine peripheral blood mononuclear cell proliferation is ameliorated after blocking the immune-inhibitory programmed death 1 receptor حسب Suleman M.

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Nanotargeted Delivery of Immune Therapeutics in Type 1 Diabetes حسب Jung, Sungwook

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The Expression of TBC1 Domain Family, Member 4 (TBC1D4) in Skeletal Muscles of Insulin-Resistant Mice in Response to Sulforaphane حسب Rizk, Nasser M

"…Sulforaphane (SFN) has been suggested as a new potential anti-diabetic compound acting by reducing blood glucose levels through mechanisms not fully understood (1). …"
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Drastic difference between hole and electron injection through the gradient shell of Cd: XSeyZn1- xS1- y quantum dots حسب Abdellah, Mohamed

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Thiostrepton inhibits growth and induces apoptosis by targeting FoxM1/SKP2/MTH1 axis in B-precursor acute lymphoblastic leukemia cells حسب Kuttikrishnan, Shilpa

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Towards An Effective Urban Growth Management Strategy In Qatar (1) حسب Al Thani, F. A. Rahman

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Inner sphere oxidation of N,N′-ethylenebis(isonitrosoacetyleacetoneimine)copper(II) by N-bromosuccinimide in aqueous weakly acidic solutions حسب Salih, Isam M.

"…The mechanism of the title reaction is consistent with an inner sphere mechanism in which a pre-equilibrium step precedes the electron transfer step. …"
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Erratum: ITRAQ-based Quantitative Protein Expression Profiling and MRM Verification of Markers in Type 2 Diabetes (Journal of Proteome Research (2012) 11 (5527-5537) DOI: 10.1021/p... حسب Kaur, Prabhjit

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Enhanced boron removal by electricity generation in a microbial fuel cell حسب Ping, Qingyun

"…Two scenarios were examined, the MFC as a pretreatment process and the MFC as a post-treatment step in connection with conventional desalination. …"
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Effect of BPA on CYP450s expression, and nicotine modulation, in fetal rat brain حسب Mohammad H., Merii

"…Fetal brains were isolated at gestational days GD14 and GD19, and protein expression was assessed by Western blotting. Results showed a BPA-induced significant decrease in CYP1B1 expression levels at GD14 (p = 0.001), and CYP19A1 (aromatase) expression at both mid- and late-stage development (p < 0.001). …"
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SIRT1 may play a crucial role in overload-induced hypertrophy of skeletal muscle حسب Koltai, Erika

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The Cellular Interplay Between Na+/H+ Exchanger Isoform I and Osteopontin in Cardiac Hypertrophy حسب Abdelaziz, Iman Ahmed

"…Protein content and ANP mRNA expression were also significantly increased in NHE1-infected cardiomyocytes, however they were significantly abrogated in the presence of OPN-siRNA (87.8±12.58% vs. 136.8±11% NHE1-infected) and (64.6±19.9% vs. 247.7±30.81% NHE1-infected). …"
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Combined Noncoding RNA-mRNA Regulomics Signature in Reprogramming and Pluripotency in iPSCs حسب Salloum-Asfar, Salam

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Effect of plastic deformation on Corrosion of cadmium in 0.1 m sodium Sulphate solution حسب Kandeil, A. Y. [عبد الرزاق يوسف قنديل]

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Synthesis of Metallocene Catalyzed Ethylene 1,7-Octadiene Copolymer: Effect of Copolymerization on Polymer Properties حسب Rahaman M.

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Preparation and characterization of chemically synthesized polyaniline–polystyrene blends as a carbon dioxide gas sensor حسب J., Bhadra

"…The SEM results of the above polymerized blends reflect the formation of spherical nanoparticles with diameter ranging from 50nm to 90nm with a decrease in PS concentration that facilitates the formation of clusters. …"
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