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Structural analysis of missense mutations in galactokinase 1 (GALK1) leading to galactosemia type-2.
Published 2018“…Molecular docking analysis revealed a decrease in interaction between the protein and ATP in all the 3 mutations, and molecular dynamic simulations of 50 ns showed a loss of stability and compactness in the mutant proteins. …”
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Global, regional, and national stillbirths at 20 weeks' gestation or longer in 204 countries and territories, 1990–2021: findings from the Global Burden of Disease Study 2021
Published 2024“…The estimated number of stillbirths occurring at 20 weeks' gestation or longer decreased from 5·08 million (95% UI 4·07–6·35) in 1990 to 3·04 million (2·61–3·62) in 2021, corresponding to a 39·8% (31·8–48·0) reduction, which lagged behind a global improvement in neonatal deaths of 45·6% (36·3–53·1) for the same period (down from 4·03 million [3·86–4·22] neonatal deaths in 1990). …”
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The Expression of TBC1 Domain Family, Member 4 (TBC1D4) in Skeletal Muscles of Insulin-Resistant Mice in Response to Sulforaphane
Published 2020“…Methodology: C57BL/6 mice (n=20) were fed with a high fat diet (60%) for 16 weeks to generate diet induced obese (DIO) mice with body weights between 45–50 gm. …”
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Inner sphere oxidation of N,N′-ethylenebis(isonitrosoacetyleacetoneimine)copper(II) by N-bromosuccinimide in aqueous weakly acidic solutions
Published 2013“…The mechanism of the title reaction is consistent with an inner sphere mechanism in which a pre-equilibrium step precedes the electron transfer step. …”
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Enhanced boron removal by electricity generation in a microbial fuel cell
Published 2016“…In the post-treatment mode, the MFC removed 80–90% of boron and decreased the boron concentration from 20 to 2 mg L− 1 or from 5 to 1 mg L− 1, which meets the irrigation water requirement. …”
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Effect of BPA on CYP450s expression, and nicotine modulation, in fetal rat brain
Published 2022“…Fetal brains were isolated at gestational days GD14 and GD19, and protein expression was assessed by Western blotting. Results showed a BPA-induced significant decrease in CYP1B1 expression levels at GD14 (p = 0.001), and CYP19A1 (aromatase) expression at both mid- and late-stage development (p < 0.001). …”
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The Cellular Interplay Between Na+/H+ Exchanger Isoform I and Osteopontin in Cardiac Hypertrophy
Published 2014“…This was significantly abolished in the presence of siRNA-OPN (20.2 fold decrease±0.12 of control) and (68.5±0.24% vs. 586.5±103.54% NHE1-infected). …”
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Comparing Methods for Induction of Insulin Resistance in Mouse 3T3-L1 Cells.
Published 2024“…TNFα reduced cell proliferation by 10-20%, and chronic TNFα treatment significantly decreased mature adipocytes due to its cytotoxicity. …”
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Preparation and characterization of chemically synthesized polyaniline–polystyrene blends as a carbon dioxide gas sensor
Published 2013“…The SEM results of the above polymerized blends reflect the formation of spherical nanoparticles with diameter ranging from 50nm to 90nm with a decrease in PS concentration that facilitates the formation of clusters. …”
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Qatar Culture Collection of Microalgae: A Sustainable Source for Biodiesel Production and Omega Fatty Acid Compounds
Published 2016“…A one step transesterification process was used to derivitize the intrinsic lipid into fatty acid methyl esters and the individual components were identified against known standards. …”
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Experimental and numerical investigation of the flexural behavior of one-way RC slabs strengthened with near-surface mounted and externally bonded systems
Published 2024“…In contrast, the slabs reinforced with EB experienced a decrease in ductility ranging from 38 % to 50 %. …”
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Box-Behnken approach for optimization of Cr(III) removal from a real tanning effluent using powdered marble
Published 2022“…Microtoxicity (Escherichia coli) assays showed a decrease in the growth inhibition percentage going from 100 to 31% following the adsorption experiment using raw tanning effluent. …”
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Coral reef resilience differs among islands within the Gulf of Mannar, southeast India, following successive coral bleaching events
Published 2021“…Overall, between 2005 and 2017 reefs had a simultaneous decrease in relative coral cover (avg. = ? …”
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Signaling pathways activated by PACAP in MCF-7 breast cancer cells
Published 2018“…Results showed that MCF-7 cells express VPAC1 and VPAC2, but not PAC1, receptors. In addition, PACAP increased the phosphorylation levels of STAT1, Src and Raf within seconds, confirming their involvement in early stages of PACAP signaling whereas maximal phosphorylation of AKT, ERK and p38 was reached 10 to 20 min later. …”
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MOLECULAR FEATURES OF TRIPLE NEGATIVE BREAST CANCER STEM CELLS: A GENE EXPRESSION PROFILING ANALYSIS OF MDA-MB-231 CELLS
Published 2021“…Triple negative breast cancer (TNBC) is a chemoresistant subtype of female breast tumors. …”
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