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point decrease » point increase (Expand Search)
nn decrease » _ decrease (Expand Search), mean decrease (Expand Search), gy decreased (Expand Search)
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c decrease » c decreased (Expand Search), _ decrease (Expand Search), rc decreased (Expand Search)
5 point » _ point (Expand Search)
5 c » 25 c (Expand Search)
point decrease » point increase (Expand Search)
nn decrease » _ decrease (Expand Search), mean decrease (Expand Search), gy decreased (Expand Search)
a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
c decrease » c decreased (Expand Search), _ decrease (Expand Search), rc decreased (Expand Search)
5 point » _ point (Expand Search)
5 c » 25 c (Expand Search)
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FTY720 treatment decreased tumor growth in a xenograft model of hepatoblastoma.
Published 2019“…<p>(A) HuH6 cells (2.5 x 10<sup>6</sup> cells in 25% Matrigel) were injected subcutaneously into the right flank of 6-week-old female athymic nude mice. …”
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Results for K<sub>s</sub>/D = 8.8 × 10<sup>−5</sup>, (a) Power, (b) Frequency, and (c) Amplitude.
Published 2025Subjects: -
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Results for K<sub>s</sub>/D = 5.08 × 10<sup>−4</sup>, (a) Power, (b) Frequency, and (c) Amplitude.
Published 2025Subjects: -
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Adaptation to cool temperature decreases basal and stimulated lipolysis and increases <i>de novo</i> lipogenesis and TAG synthesis.
Published 2021“…(<b>C</b>) Cool adaptation increases expression of lipases but decreases phosphorylation of perilipin and HSL in response to CL-316,243. …”
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Validation of primary screen hits reveals compounds that recapitulate increased spheroid size (swell) or decreased MUC5AC in the lumen.
Published 2023“…Compounds that appeared to cause toxicity were identified by observing a significant decrease in spheroid counts in the swell readout or a significant decrease in the total nuclear intensity of the MUC5AC ratio readout. …”
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FTY720 decreased viability, proliferation, and motility and induced apoptosis in human hepatoblastoma cells.
Published 2019“…(B) Following 24 hours of treatment with FTY720, the proliferation of HuH6 cells measured using the CellTiter 96 cell proliferation assay was significantly decreased (IC<sub>50</sub> = 6.4 μM, p ≤ 0.05). (C) HuH6 cells were plated and allowed to reach 80% confluence, at which time the media was changed for fresh media (0, 5, or 8 μM FTY720) and a standard scratch wound was made. …”
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