Selective TASK‑1 Inhibitor with a Defined Structure–Activity Relationship Reduces Cancer Cell Proliferation and Viability by Bárbara Arévalo (4053358)

“…Mutation of seven residues to A (I118A, L122A, F125A, Q126A, L232A, I235A, and L239A) markedly decreased the F3-induced inhibition of TASK-1 channels, consistent with the molecular modeling predictions. …”

Selective TASK‑1 Inhibitor with a Defined Structure–Activity Relationship Reduces Cancer Cell Proliferation and Viability by Bárbara Arévalo (4053358)

“…Mutation of seven residues to A (I118A, L122A, F125A, Q126A, L232A, I235A, and L239A) markedly decreased the F3-induced inhibition of TASK-1 channels, consistent with the molecular modeling predictions. …”

S5 Data - by Ayuta Kishimoto (16814662)

Atomically Precise Au₄₂ Nanorods with Longitudinal Excitons for an Intense Photothermal Effect by Yingwei Li (701628)

Subjects:

Five genes involved in piRNA biosynthesis were commonly down-regulated in the two <i>enok</i> mutants as compared with the WT control, while the expression levels of <i>piwi</i>, <i>AGO3</i> and <i>aub</i> were not decreased in <i>enok</i> mutants. by Shih-Ying Tsai (3576587)

Comparison of the histopathological changes after KA/E2 treatment in WT and TLR2 KO mice. by Mi-Kyung Park (56053)

The bioluminescent responses of the pILAnrsRS constructs in the two nrsRS promoter orientations in WT and NiCoZia strains. by Gábor Patyi (11846776)

Fibγ^Δ5 mice display decreased survival following <i>S. aureus</i> peritonitis. by Oscar Negrón (11965511)

Definitions of the features selected [50]. by Yu Zhang (12946)

Defects in the conduction of somatosensory evoked potentials of median and tibial nerves in a healthy child and in H-ABC patient. by Jose R. Eguibar (8563227)

Changes in cyanobacteria fluorescence with 75 μg/mL H₂O₂ for 5, 8, 17 and 24 days. by Emma T. Brentjens (17295999)

Subjects:

Solvent Entrapment of BI 763963 by Solid Solution Formation by Samruddhi Patil (11523791)

“…Two binary T-w phase diagrams were constructed showing the outline of the solidus and liquidus, where EtOH and IPA are present in the solid phase of BI 763963 at 0.54 and 1.5 wt %, respectively, at equilibrium. Importantly, the solvent solubility of BI 763963 was found to be dependent on the residual solvent level in the solid phase and in the case of EtOH increased by almost 50% at just 1.1 wt % EtOH entrapment. …”

Machine Learning Accelerates Discovery of Optimal Colloidal Quantum Dot Synthesis by Oleksandr Voznyy (1376316)

Subjects:

E2 induces increased chromosome conformation capture contact frequencies but decreased proximity between enhancers and promoters. by Luciana I. Gómez Acuña (18605719)

Identification of novel, small molecule TTBK1 inhibitor which dose dependently decreases tau phosphorylation at S422. by Gregory M. Dillon (8681430)

H2-K^b overexpression decreases NSPC proliferation and impairs adult hippocampal neurogenesis. by Karin Lin (11037548)

Δ<i>gra72</i> parasites form bubble vacuoles with decreased PVM permeability to small molecules. by Tatiana C. Paredes-Santos (16699433)

Proviral load in blood was decreased in HTLV-1 infected CD133+ Hu-mice when vCTCF-BS was deleted. by Ancy Joseph (5634794)

Spatial training decreases the association between Ndfip1 and Nedd4 and decreases endogenous Beclin 1 ubiquitination in the hippocampus. by Wei-Lun Hsu (1756123)

Decreasing patterns of P_WT scores in 6 conditions with individual values (0.05, 0.1, 0.2, 0.3, 0.4, and 0.5). by In Seok Yang (4261207)