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61
Signaling pathways activated by PACAP in MCF-7 breast cancer cells
Published 2018“…In conclusion, we demonstrated that PACAP signaling in MCF-7 cells follows the Src/Raf/ERK and PI3K/AKT pathways and is VPAC1 dependent in a ROS dependent manner, whereas it follows PLC and PKA/cAMP pathways and is VPAC2 dependent through p38 MAP kinase activation involving calcium.…”
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The role of soluble uric acid in modulating autophagy flux and inflammasome activation during bacterial infection in macrophages
Published 2020“…We observed that IL-1β increased during bacterial infection but decreased when macrophages were co-stimulated with bacteria and uric acid. …”
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64
MYD88, IRAK3 and Rheumatoid Arthritis pathogenesis: Analysis of differential gene expression in CD14 + monocytes and the inflammatory cytokine levels.
Published 2021“…Two molecular players act in the inflammation balance of the disease: MyD88 (Myeloid differentiation primary response 88) is related to TLR (Toll-like receptors) response and promotes the formation of myddosome complex resulting in increased inflammation; IRAK3 (Interleukin-1 receptor associated kinase 3) acts suppressing the myddosome complex thus decreasing inflammation. …”
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65
Chronic melatonin treatment improves obesity by inducing uncoupling of skeletal muscle SERCA-SLN mediated by CaMKII/AMPK/PGC1α pathway and mitochondrial biogenesis in female and ma...
Published 2024“…Melatonin treatment increased the SERCA2 expression in obese and lean rats (both sexes), with no effects on SERCA1 expression. Melatonin increased the expression of thermogenic genes and proteins (PGC1-α, PPARγ, and NRF1). …”
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66
A novel index based on planktonic copepod reproductive traits as a tool for marine ecotoxicology studies
Published 2020“…At high concentrations, cadmium and silver induce an increase in EPR in the copepods Acartia tonsa and Acartia hudsonica, while exposure to mercury decreases EPR in adults by 50%. All three metals affect HS, with mercury inducing a stronger effect than cadmium and silver. …”
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67
Algal-algal bioflocculation enhances the recovery efficiency of Picochlorum sp. QUCCCM130 with low auto-settling capacity
Published 2023“…QUCCCM31 and Tetraselmis sp. QUCCCM50 presenting a cell size of ∼2 μm, ∼5 μm, and ∼15 μm, respectively, were selected to be subjected to the harvesting optimisation experiments. …”
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68
Interfaces study of all-polysaccharide composite films
Published 2018“…The lowest OT temperature was observed at QC/X = 1/3. We think it is due to the thermocatalytic effect of the 4-O-methyl-D-glucuronate in X and the QC quaternary groups on the thermolysis–thermo-oxidation mechanism. …”
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Appropriateness of gentamicin therapeutic drug monitoring at a Middle Eastern tertiary hospital setting: a retrospective evaluation and quality audit
Published 2024“…Objective: This study aimed to evaluate the appropriateness of gentamicin therapeutic drug monitoring (TDM) at a tertiary care hospital in Qatar. Methods: A one-year quantitative retrospective chart review of all gentamicin TDM records was conducted. …”
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70
Advanced Hard Ctings: Towards A Whole New World
Published 2014“…That is where advanced surface coatings come in. From a manufacturing point of view, tools for machining are of particular interest. …”
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71
Elaeagnus Angustifolia: a Promising Medicinal Plant for Cancer Theraby
Published 2020“…However, the effect of EA plant extract on human cancer progression especially oral malignancy has not been investigated yet. Thus, first we examined the effect of EA flower extract on angiogenesis in ovo, and on selected parameters in human oral cancer cells. …”
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A Multi-echelon Network Distribution Model For Emergency Resource Planning
Published 2014“…(Acknowledgement: Qatar/QNRF/NPRP Project: 5-200-5-027)…”
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73
A disease-modifying treatment for Alzheimer's disease: Focus on the trans-sulfuration pathway
Published 2019“…There is a decrease in aconitase 1 (ACO1) in AD. ACO1 is an iron-sulfur enzyme in the citric acid cycle that upon loss of an iron-sulfur cluster converts to iron regulatory protein 1 (IRP1). …”
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Fabrication of Selective Sensors for Hg2+ Traces in Water Using Graphene Decorated with Metal Nanoclusters
Published 2016“…Each Hg2+ sensor was fabricated using (1 cm × 1 cm) commercial graphene layer on SiO2/doped-Si substrate (thickness of SiO2 is 285 nm, and Si is p-type with resistivity of 0.001-0.005 ohm.cm). …”
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76
A Reconfigurable Multipurpose SoC Mobile Platform for metal detection
Published 2018“…Zaman, «Efficient design of a metal detector equipped remote-controlled robotic vehicle,» 2016 International Conference on Microelectronics, Computing and Communications (MicroCom), Durgapur, 2016, pp. 1-5 [3] «Cyclone V Device Overview», Altera, 2016. …”
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77
Implementing and Analyzing a Recursive Technique for Building Path Oblivious RAM
Published 2018“…We tested our implementation on 1 million items using several threshold sizes of position map. …”
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A systematic review of stability of medicines used in emergency medical service settings
Published 2020“…In the GCC region including Qatar, temperature and relative humidity values may rise over 50°C and 80%, respectively, according to climate data from the Qatar Civil Aviation Authority 3 . …”
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Divergent Biochemical Properties and Disparate Impact of Arrhythmogenic Calmodulin Mutations on Zebrafish Cardiac Function
Published 2024“…Herein, we investigate in vivo functional effects of these CaM mutations on the normal zebrafish embryonic heart function by microinjecting complementary RNA corresponding to CaMN98I, CaMD132E, CaMD134H, and CaMQ136P mutants. …”
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