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nn decrease » _ decrease (Expand Search)
wt decrease » _ decrease (Expand Search)
a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
a gene » _ gene (Expand Search), 1 gene (Expand Search), a genome (Expand Search)
2 wt » _ wt (Expand Search), i wt (Expand Search)
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Protein arginine methyltransferase 5 (PRMT5) promotes survival of lymphoma cells via activation of WNT/B-catenin and AKT/GSK3B proliferative signaling
Published 2019“…We show that PRMT5 stimulates WNT/B-CATENIN signaling through direct epigenetic silencing of pathway antagonists, AXIN2 and WIF1, and indirect activation of AKT/GSK3 signaling.PRMT5 inhibition with either shRNA-mediated knockdown or a specific small molecule PRMT5 inhibitor, CMP-5, not only leads to derepression of WNT antagonists and decreased levels of active phospho-AKT (Thr-450 and Ser-473) and inactive phospho- GSK3B (Ser-9) but also results in decreased transcription of WNT/B-CATENIN target genes, CYCLIN D1, c-MYC, and SURVIVIN, and enhanced lymphoma cell death. …”
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363
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Na + /H + exchanger isoform 1-induced osteopontin expression facilitates cardiac hypertrophy through p90 ribosomal S6 kinase
Published 2018“…The Na+/H+ exchanger isoform 1 (NHE1), a multifunctional protein and the key pH regulator in the heart, has been demonstrated to be increased in this condition. …”
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365
Binding energy, structural, and dielectric properties of thin film of poly(aniline-co-m-fluoroaniline)
Published 2018“…The permittivity of copolymer PA-co-m-FA50 has a higher value than polyaniline in the high-frequency regime and decreases with the increase of frequency. …”
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366
Comparative Study on Beneficial Effects of Hydroxytyrosol- and Oleuropein-Rich Olive Leaf Extracts on High-Fat Diet-Induced Lipid Metabolism Disturbance and Liver Injury in Rats
Published 2020“…Equally, it showed a rise of the apoptotic markers (a decrease in the expression of the Bcl-2 and an increase of the P53). …”
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367
Glycine and Folate Ameliorate Models of Congenital Sideroblastic Anemia
Published 2016“…A common subtype of congenital sideroblastic anemia is due to autosomal recessive mutations in the SLC25A38 gene. …”
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368
Impact of composition and salinity on swelling and gel strength of poly (acrylamide-co-acrylic acid) preformed particle gel
Published 2023“…The effects of various material compositions and reservoir environments on the ultimate strength and swelling kinetics of a commercial preformed particle gel (PPG) have been investigated. …”
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369
Development And Performance Evaluation Of Smart Polymeric Coatings For Corrosion Protection Of Steel
Published 2020“…The prepared microcapsules (each 6.0 wt.% ) were uniformly dispersed into the epoxy resin to develop single layer coatings (reinforced with urea formaldehyde microcapsules) and multilayered smart coatings (reinforced with multilayered microcapsules). …”
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370
Computational model to analyze and characterize the functional mutations of NOD2 protein causing inflammatory disorder - Blau syndrome.
Published 2020“…This study is expected to serve as a platform for developing targeted drug therapy for BS.…”
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371
Awareness of disabilities in pharmacy program recruitment material: are we doing enough?
Published 2020“…Introduction: Targeted recruitment of students with disabilities is a novel area in pharmacy education and may help to attract qualified students in light of decreasing applicant numbers. …”
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372
Mechanical and physical behavior of newly developed functionally graded materials and composites of stainless steel 316L with calcium silicate and hydroxyapatite
Published 2015“…Compressive mechanical properties of SS-316L/HA decreased sharply with increasing of HA content up to 20. wt% and gradually with CS content up to 50. wt% for SS-316L/CS composites. …”
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Biodegradable thermoplastic polyurethane composites as potential plating systems in pediatric facial fractures
Published 2022“…Due to the rapid growth of facial bone in the pediatric age group, the use of metallic plates would require a second surgical intervention to remove it. The alternative is biodegradable plating systems which are safe but not without complications, including learning curve, decreased stability, cost, and infection. …”
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Hot and Hypoxic environments inhibit simulated soccer performance and exacerbate performance decrements when combined
Published 2016“…Twelve male University soccer players completed three familiarization sessions and four randomized crossover experimental trials of the intermittent Soccer Performance Test (iSPT)in normoxic- temperate(CON:18◦C50%rH),HOT(30◦C;50%rH),HYP(1000m;18◦C50%rH),and HH(1000m;30◦C;50%rH).Physical performance and its performance decrements, bodytemperatures(rectal,skin,and estimated muscle temperature), heartrate(HR), arterial blood oxygen saturation(SaO2), perceived exertion, thermal sensation(TS), body mass changes, blood lactate, and plasma volume were all measured. …”
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379
Ni-P-TiO2 Composite coatings on copper produced by sol-enhanced electroplating
Published 2014“…Ni-P-TiO2 composite coatings were prepared on copper substrate by TiO2 sol-enhanced electroplating. A systematic study of Ni-P-X coatings with different sol concentrations (TiO2 concentration X from 0 to 50 mL/L) has been conducted in order to understand the effect of TiO2 sol addition and the strengthening mechanism. …”
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380
Shiitake Culinary-Medicinal Mushroom, Lentinus edodes (Agaricomycetes), Supplementation Alters Gut Microbiome and Corrects Dyslipidemia in Rats.
Published 2019“…Wistar rats were offered a chow maintenance diet (CMD; CON group) or the same CMD ration with cholesterol (1.5% w/w) and cholic acid (0.5% w/w) added to induce hypercholesterolemia (day 1 to day 24). …”
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